The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 436 | 2013 |
Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling S Roy, S Plowman, B Rotblat, IA Prior, C Muncke, S Grainger, RG Parton, ... Molecular and cellular biology 25 (15), 6722-6733, 2005 | 263 | 2005 |
Galectin-1 (L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP B Rotblat, H Niv, S André, H Kaltner, HJ Gabius, Y Kloog Cancer research 64 (9), 3112-3118, 2004 | 185 | 2004 |
Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane B Rotblat, IA Prior, C Muncke, RG Parton, Y Kloog, YI Henis, JF Hancock Molecular and cellular biology 24 (15), 6799-6810, 2004 | 184 | 2004 |
Identification of an essential component of the elicitation active site of the EIX protein elicitor B Rotblat, D Enshell‐Seijffers, JM Gershoni, S Schuster, A Avni The Plant Journal 32 (6), 1049-1055, 2002 | 177 | 2002 |
Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis J Musa, MF Orth, M Dallmayer, M Baldauf, C Pardo, B Rotblat, T Kirchner, ... Oncogene 35 (36), 4675-4688, 2016 | 168 | 2016 |
Galectin-1 is a novel structural component and a major regulator of h-ras nanoclusters L Belanis, SJ Plowman, B Rotblat, JF Hancock, Y Kloog Molecular biology of the cell 19 (4), 1404-1414, 2008 | 162 | 2008 |
K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3 R Shalom-Feuerstein, SJ Plowman, B Rotblat, N Ariotti, T Tian, ... Cancer research 68 (16), 6608-6616, 2008 | 160 | 2008 |
The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells G Mazor, L Levin, D Picard, U Ahmadov, H Carén, A Borkhardt, ... Cell death & disease 10 (3), 246, 2019 | 135 | 2019 |
Stress-mediated translational control in cancer cells G Leprivier, B Rotblat, D Khan, E Jan, PH Sorensen Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (7), 845-860, 2015 | 134 | 2015 |
The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer B Rotblat, M Ehrlich, R Haklai, Y Kloog Methods in enzymology 439, 467-489, 2008 | 130 | 2008 |
NRF2 and p53: Januses in cancer? B Rotblat, G Melino, RA Knight Oncotarget 3 (11), 1272, 2012 | 128 | 2012 |
High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy M Rossi, B Rotblat, K Ansell, I Amelio, M Caraglia, G Misso, F Bernassola, ... Cell death & disease 5 (5), e1203-e1203, 2014 | 125 | 2014 |
Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities V Landré, B Rotblat, S Melino, F Bernassola, G Melino Oncotarget 5 (18), 7988, 2014 | 115 | 2014 |
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes M Daugaard, R Nitsch, B Razaghi, L McDonald, A Jarrar, S Torrino, ... Nature communications 4 (1), 2180, 2013 | 111 | 2013 |
Apoptotic cell death in disease—Current understanding of the NCCD 2023 I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 30 (5), 1097-1154, 2023 | 108 | 2023 |
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response B Rotblat, AL Southwell, DE Ehrnhoefer, NH Skotte, M Metzler, ... Proceedings of the National Academy of Sciences 111 (8), 3032-3037, 2014 | 107 | 2014 |
Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch U Ashery, O Yizhar, B Rotblat, G Elad-Sfadia, B Barkan, R Haklai, Y Kloog Cellular and molecular neurobiology 26, 469-493, 2006 | 92 | 2006 |
How does mTOR sense glucose starvation? AMPK is the usual suspect G Leprivier, B Rotblat Cell death discovery 6 (1), 27, 2020 | 79 | 2020 |
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes J Musa, F Cidre-Aranaz, MM Aynaud, MF Orth, MML Knott, O Mirabeau, ... Nature communications 10 (1), 4128, 2019 | 58 | 2019 |