| Sorafenib treatment of FLT3-ITD+ acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the … CH Man, TK Fung, C Ho, HHC Han, HCH Chow, ACH Ma, WWL Choi, ... Blood, The Journal of the American Society of Hematology 119 (22), 5133-5143, 2012 | 341 | 2012 |
| FLT3 inhibition: a moving and evolving target in acute myeloid leukaemia AYH Leung, CH Man, YL Kwong Leukemia 27 (2), 260-268, 2013 | 146 | 2013 |
| Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia BL He, X Shi, CH Man, ACH Ma, SC Ekker, HCH Chow, CWE So, ... Blood, The Journal of the American Society of Hematology 123 (16), 2518-2529, 2014 | 69 | 2014 |
| Inhibition of NOTCH3 signalling significantly enhances sensitivity to cisplatin in EBV‐associated nasopharyngeal carcinoma CH Man, S Wei‐Man Lun, J Wai‐Ying Hui, KF To, KW Choy, ... The Journal of pathology 226 (3), 471-481, 2012 | 66 | 2012 |
| Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia SSY Lam, ESK Ho, BL He, WW Wong, CY Cher, NKL Ng, CH Man, H Gill, ... Science translational medicine 8 (359), 359ra129-359ra129, 2016 | 62 | 2016 |
| Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia CH Man, TK Fung, H Wan, CY Cher, A Fan, N Ng, C Ho, TSK Wan, ... Blood, The Journal of the American Society of Hematology 125 (25), 3928-3936, 2015 | 55 | 2015 |
| A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML CH Man, SSY Lam, MKH Sun, HCH Chow, H Gill, YL Kwong, AYH Leung Blood, The Journal of the American Society of Hematology 123 (16), 2530-2539, 2014 | 51 | 2014 |
| Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis YP Wang, A Sharda, SN Xu, N Van Gastel, CH Man, U Choi, WZ Leong, ... Cell metabolism 33 (5), 1027-1041. e8, 2021 | 42 | 2021 |
| Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth CH Man, FE Mercier, N Liu, W Dong, G Stephanopoulos, L Jiang, Y Jung, ... Blood, The Journal of the American Society of Hematology 139 (4), 502-522, 2022 | 32 | 2022 |
| Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish X Shi, BL He, ACH Ma, Y Guo, Y Chi, CH Man, W Zhang, Y Zhang, Z Wen, ... Blood, The Journal of the American Society of Hematology 125 (19), 2974-2984, 2015 | 31 | 2015 |
| COVID‐19 metabolism: Mechanisms and therapeutic targets T Wang, Y Cao, H Zhang, Z Wang, CH Man, Y Yang, L Chen, S Xu, X Yan, ... MedComm 3 (3), e157, 2022 | 25 | 2022 |
| Follistatin is a novel therapeutic target and biomarker in FLT 3/ITD acute myeloid leukemia BL He, N Yang, CH Man, NKL Ng, CY Cher, HC Leung, LLH Kan, ... EMBO molecular medicine 12 (4), e10895, 2020 | 18 | 2020 |
| Mechanical oscillations enhance gene delivery into suspended cells ZL Zhou, XX Sun, J Ma, CH Man, AST Wong, AY Leung, AHW Ngan Scientific reports 6 (1), 22824, 2016 | 16 | 2016 |
| Azacitidine as post-remission consolidation for sorafenib-induced remission of Fms-like tyrosine kinase-3 internal tandem duplication positive acute myeloid leukemia H Gill, CH Man, AHW Ip, WWL Choi, HCH Chow, YL Kwong, AYH Leung Haematologica 100 (7), e250, 2015 | 15 | 2015 |
| In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies FE Mercier, J Shi, DB Sykes, T Oki, M Jankovic, CH Man, YS Kfoury, ... Blood Advances 6 (17), 5072-5084, 2022 | 8 | 2022 |
| Redefining prognostication of de novo cytogenetically normal acute myeloid leukemia in young adults SP Tsui, HW Ip, NY Saw, C Zhang, AK Cheung, NK Ng, CH Man, SS Lam, ... Blood Cancer Journal 10 (10), 104, 2020 | 7 | 2020 |
| Cell-structure specific necrosis by optical-trap induced intracellular nuclear oscillation XX Sun, ZL Zhou, CH Man, AYH Leung, AHW Ngan Journal of the mechanical behavior of biomedical materials 66, 58-67, 2017 | 7 | 2017 |
| Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML CH Man, W Lam, CC Dang, X Zeng, LC Zheng, NNM Chan, KL Ng, ... Blood 142 (23), 2002-2015, 2023 | 5 | 2023 |
| A genome-wide, in vivo, dropout CRISPR screen in acute myeloid leukemia identifies an essential role for beta-galactosylation in leukemic cell homing F Mercier, J Shi, DB Sykes, E Miller, T Oki, CH Man, XJ Yan, Y Kfoury, ... Blood 130, 2493, 2017 | 5 | 2017 |
| A Zebrafish Model of FMS-Like Tyrosine Kinase 3 (FLT3) in definitive hematopoiesis and human acute myeloid leukemia B He, CH Man, X Shi, ACH Ma, AYH Leung Experimental Hematology 41 (8), S48, 2013 | 3 | 2013 |
