| Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection KR Chan, SLX Zhang, HC Tan, YK Chan, A Chow, APC Lim, ... Proceedings of the National Academy of Sciences 108 (30), 12479-12484, 2011 | 161 | 2011 |
| Structure-guided design of an anti-dengue antibody directed to a non-immunodominant epitope LN Robinson, K Tharakaraman, KJ Rowley, VV Costa, KR Chan, ... Cell 162 (3), 493-504, 2015 | 138 | 2015 |
| Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue KR Chan, EZ Ong, HC Tan, SLX Zhang, Q Zhang, KF Tang, ... Proceedings of the National Academy of Sciences 111 (7), 2722-2727, 2014 | 125 | 2014 |
| Cross-reactive antibodies enhance live attenuated virus infection for increased immunogenicity KR Chan, X Wang, WAA Saron, ES Gan, HC Tan, DZL Mok, SLX Zhang, ... Nature microbiology 1 (12), 1-10, 2016 | 91 | 2016 |
| Dengue E protein domain III-based DNA immunisation induces strong antibody responses to all four viral serotypes M Poggianella, JL Slon Campos, KR Chan, HC Tan, M Bestagno, EE Ooi, ... PLoS neglected tropical diseases 9 (7), e0003947, 2015 | 62 | 2015 |
| The effects of pre-existing antibodies on live-attenuated viral vaccines DZL Mok, KR Chan Viruses 12 (5), 520, 2020 | 59 | 2020 |
| Fc receptors and their influence on efficacy of therapeutic antibodies for treatment of viral diseases KR Chan, EZ Ong, DZL Mok, EE Ooi Expert review of anti-infective therapy 13 (11), 1351-1360, 2015 | 54 | 2015 |
| Dengue virus neutralization in cells expressing Fc gamma receptors T Chawla, KR Chan, SL Zhang, HC Tan, APC Lim, BJ Hanson, EE Ooi PloS one 8 (5), e65231, 2013 | 42 | 2013 |
| Metabolic perturbations and cellular stress underpin susceptibility to symptomatic live-attenuated yellow fever infection KR Chan, ES Gan, CYY Chan, C Liang, JZH Low, SLX Zhang, EZ Ong, ... Nature Medicine 25 (8), 1218-1224, 2019 | 40 | 2019 |
| A systematic approach to the development of a safe live attenuated Zika vaccine SS Kwek, S Watanabe, KR Chan, EZ Ong, HC Tan, WC Ng, MTX Nguyen, ... Nature communications 9 (1), 1031, 2018 | 39 | 2018 |
| The mechanistic role of antibodies to dengue virus in protection and disease pathogenesis ES Gan, DHR Ting, KR Chan Expert Review of Anti-Infective Therapy 15 (2), 111-119, 2017 | 38 | 2017 |
| Dengue virus compartmentalization during antibody-enhanced infection EZ Ong, SL Zhang, HC Tan, ES Gan, KR Chan, EE Ooi Scientific Reports 7 (1), 40923, 2017 | 33 | 2017 |
| Adverse effects following anti–COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T … A Syenina, ES Gan, JZN Toh, R de Alwis, LZ Lin, CYL Tham, JX Yee, ... PLoS Biology 20 (5), e3001643, 2022 | 31 | 2022 |
| Rational engineering and characterization of an mAb that neutralizes Zika virus by targeting a mutationally constrained quaternary epitope K Tharakaraman, S Watanabe, KR Chan, J Huan, V Subramanian, ... Cell host & microbe 23 (5), 618-627. e6, 2018 | 31 | 2018 |
| Therapeutic antibodies as a treatment option for dengue fever KR Chan, EZ Ong, EE Ooi Expert review of anti-infective therapy 11 (11), 1147-1157, 2013 | 31 | 2013 |
| Signatures of mast cell activation are associated with severe COVID-19 J Tan, DE Anderson, APS Rathore, A O’Neill, CK Mantri, WAA Saron, ... medRxiv, 2021.05. 31.21255594, 2021 | 27 | 2021 |
| Antibody-Dependent dengue virus entry modulates cell intrinsic responses for enhanced infection CYY Chan, JZH Low, ES Gan, EZ Ong, SLX Zhang, HC Tan, X Chai, ... Msphere 4 (5), 10.1128/msphere. 00528-19, 2019 | 27 | 2019 |
| Dysregulated metabolism underpins Zika-virus-infection-associated impairment in fetal development C Yau, JZH Low, ES Gan, SS Kwek, L Cui, HC Tan, DZL Mok, CYY Chan, ... Cell Reports 37 (11), 2021 | 25 | 2021 |
| The association of obesity and severe dengue: possible pathophysiological mechanisms P Gallagher, KR Chan, L Rivino, S Yacoub Journal of Infection 81 (1), 10-16, 2020 | 25 | 2020 |
| Hypoxia enhances antibody‐dependent dengue virus infection ES Gan, WF Cheong, KR Chan, EZ Ong, X Chai, HC Tan, S Ghosh, ... The EMBO Journal 36 (10), 1348-1363, 2017 | 23 | 2017 |
