Exosomes maintain cellular homeostasis by excreting harmful DNA from cells A Takahashi, R Okada, K Nagao, Y Kawamata, A Hanyu, S Yoshimoto, ... Nature communications 8 (1), 15287, 2017 | 700 | 2017 |
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2 M Takasugi, R Okada, A Takahashi, D Virya Chen, S Watanabe, E Hara Nature communications 8 (1), 15729, 2017 | 338 | 2017 |
Emerging roles of extracellular vesicles in cellular senescence and aging M Takasugi Aging cell 17 (2), e12734, 2018 | 176 | 2018 |
Universal DNA methylation age across mammalian tissues AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li, R Lowe, Q Yan, ... BioRxiv, 2021.01. 18.426733, 2021 | 99 | 2021 |
Universal DNA methylation age across mammalian tissues AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li, R Lowe, Q Yan, ... Nature aging 3 (9), 1144-1166, 2023 | 93 | 2023 |
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties M Takasugi, D Firsanov, G Tombline, H Ning, J Ablaeva, A Seluanov, ... Nature communications 11 (1), 2376, 2020 | 85 | 2020 |
Ablation of the p16INK4a tumour suppressor reverses ageing phenotypes of klotho mice S Sato, Y Kawamata, A Takahashi, Y Imai, A Hanyu, A Okuma, ... Nature communications 6 (1), 7035, 2015 | 73 | 2015 |
The role of cellular senescence and SASP in tumour microenvironment M Takasugi, Y Yoshida, E Hara, N Ohtani The FEBS journal 290 (5), 1348-1361, 2023 | 63 | 2023 |
Gasdermin D–mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma R Yamagishi, F Kamachi, M Nakamura, S Yamazaki, T Kamiya, ... Science immunology 7 (72), eabl7209, 2022 | 59 | 2022 |
DNA methylation networks underlying mammalian traits A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu, J Ablaeva, ... Science 381 (6658), eabq5693, 2023 | 55* | 2023 |
DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders S Horvath, A Haghani, N Macoretta, J Ablaeva, JA Zoller, CZ Li, J Zhang, ... Nature Aging 2 (1), 46-59, 2022 | 54 | 2022 |
DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions M Takasugi, S Yagi, K Hirabayashi, K Shiota BMC genomics 11, 1-8, 2010 | 51 | 2010 |
Cellular senescence and the tumour microenvironment M Takasugi, Y Yoshida, N Ohtani Molecular oncology 16 (18), 3333-3351, 2022 | 47 | 2022 |
Progressive age-dependent DNA methylation changes start before adulthood in mouse tissues M Takasugi Mechanisms of ageing and development 132 (1-2), 65-71, 2011 | 47 | 2011 |
SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair S Rezazadeh, D Yang, SA Biashad, D Firsanov, M Takasugi, M Gilbert, ... Aging (Albany NY) 12 (12), 11165, 2020 | 38 | 2020 |
Age-and sex-dependent DNA hypomethylation controlled by growth hormone in mouse liver M Takasugi, K Hayakawa, D Arai, K Shiota Mechanisms of ageing and development 134 (7-8), 331-337, 2013 | 26 | 2013 |
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells. Nat Commun. 2017; 8: 15287 A Takahashi, R Okada, K Nagao, Y Kawamata, A Hanyu, S Yoshimoto, ... Epub 2017/05/17. doi: 10.1038/ncomms15287. PubMed PMID: 28508895, 0 | 25 | |
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells. Nat Commun 8: 15287 A Takahashi, R Okada, K Nagao, Y Kawamata, A Hanyu, S Yoshimoto, ... | 19 | 2017 |
Epigenetic predictors of maximum lifespan and other life history traits in mammals CZ Li, A Haghani, TR Robeck, D Villar, AT Lu, J Zhang, CG Faulkes, H Vu, ... BioRxiv, 2021.05. 16.444078, 2021 | 16 | 2021 |
Characterization of naked mole‐rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits S Emmrich, A Trapp, F Tolibzoda Zakusilo, ME Straight, AK Ying, ... The EMBO Journal 41 (15), e109694, 2022 | 15 | 2022 |