| Structure of a designed protein cage that self-assembles into a highly porous cube YT Lai, E Reading, GL Hura, KL Tsai, A Laganowsky, FJ Asturias, ... Nature chemistry 6 (12), 1065-1071, 2014 | 305 | 2014 |
| Subunit architecture and functional modular rearrangements of the transcriptional mediator complex KL Tsai, C Tomomori-Sato, S Sato, RC Conaway, JW Conaway, ... Cell 157 (6), 1430-1444, 2014 | 264 | 2014 |
| A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction KL Tsai, S Sato, C Tomomori-Sato, RC Conaway, JW Conaway, ... Nature structural & molecular biology 20 (5), 611-619, 2013 | 263 | 2013 |
| Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification KL Tsai, YJ Sun, CY Huang, JY Yang, MC Hung, CD Hsiao Nucleic acids research 35 (20), 6984-6994, 2007 | 244 | 2007 |
| Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation JH Lee, R Wang, F Xiong, J Krakowiak, Z Liao, PT Nguyen, ... Molecular cell 81 (16), 3368-3385. e9, 2021 | 173 | 2021 |
| Mediator structure and rearrangements required for holoenzyme formation KL Tsai, X Yu, S Gopalan, TC Chao, Y Zhang, L Florens, MP Washburn, ... Nature 544 (7649), 196-201, 2017 | 151 | 2017 |
| Architecture of the Mediator head module T Imasaki, G Calero, G Cai, KL Tsai, K Yamada, F Cardelli, ... Nature 475 (7355), 240-243, 2011 | 147 | 2011 |
| Structure of an RNA polymerase II preinitiation complex K Murakami, KL Tsai, N Kalisman, DA Bushnell, FJ Asturias, RD Kornberg Proceedings of the National Academy of Sciences 112 (44), 13543-13548, 2015 | 112 | 2015 |
| Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly YT Lai, KL Tsai, MR Sawaya, FJ Asturias, TO Yeates Journal of the American Chemical Society 135 (20), 7738-7743, 2013 | 111 | 2013 |
| Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins KL Tsai, CY Huang, CH Chang, YJ Sun, WJ Chuang, CD Hsiao Journal of Biological Chemistry 281 (25), 17400-17409, 2006 | 101 | 2006 |
| Reconstitution of the augmin complex provides insights into its architecture and function KC Hsia, EM Wilson-Kubalek, A Dottore, Q Hao, KL Tsai, S Forth, ... Nature cell biology 16 (9), 852-863, 2014 | 94 | 2014 |
| The crystal structure of a replicative hexameric helicase DnaC and its complex with single-stranded DNA YH Lo, KL Tsai, YJ Sun, WT Chen, CY Huang, CD Hsiao Nucleic Acids Research 37 (3), 804-814, 2009 | 73 | 2009 |
| RNA m6A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability F Xiong, R Wang, JH Lee, S Li, SF Chen, Z Liao, LA Hasani, PT Nguyen, ... Cell Research 31 (8), 861-885, 2021 | 58 | 2021 |
| A noncoding RNA modulator potentiates phenylalanine metabolism in mice Y Li, Z Tan, Y Zhang, Z Zhang, Q Hu, K Liang, Y Jun, Y Ye, YC Li, C Li, ... Science 373 (6555), 662-673, 2021 | 48 | 2021 |
| Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module YC Li, TC Chao, HJ Kim, T Cholko, SF Chen, G Li, L Snyder, K Nakanishi, ... Science advances 7 (3), eabd4484, 2021 | 48 | 2021 |
| 3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound EJ Brignole, KL Tsai, J Chittuluru, H Li, Y Aye, PA Penczek, JA Stubbe, ... Elife 7, e31502, 2018 | 43 | 2018 |
| Role for the MED21-MED7 hinge in assembly of the mediator-RNA polymerase II holoenzyme S Sato, C Tomomori-Sato, KL Tsai, X Yu, M Sardiu, A Saraf, ... Journal of Biological Chemistry 291 (52), 26886-26898, 2016 | 27 | 2016 |
| The hypoxia-adenosine link during myocardial ischemia—reperfusion injury W Ruan, X Ma, IH Bang, Y Liang, JD Muehlschlegel, KL Tsai, TW Mills, ... Biomedicines 10 (8), 1939, 2022 | 23 | 2022 |
| Comparative parallel analysis of RNA ends identifies mRNA substrates of a tRNA splicing endonuclease-initiated mRNA decay pathway JE Hurtig, MA Steiger, VK Nagarajan, T Li, TC Chao, KL Tsai, A van Hoof Proceedings of the National Academy of Sciences 118 (10), e2020429118, 2021 | 22 | 2021 |
| Molecular interplay between the replicative helicase DnaC and its loader protein DnaI from Geobacillus kaustophilus KL Tsai, YH Lo, YJ Sun, CD Hsiao Journal of molecular biology 393 (5), 1056-1069, 2009 | 22 | 2009 |
