Quadruplex DNA: sequence, topology and structure S Burge, GN Parkinson, P Hazel, AK Todd, S Neidle Nucleic acids research 34 (19), 5402-5415, 2006 | 2609 | 2006 |
Crystal structure of parallel quadruplexes from human telomeric DNA GN Parkinson, MPH Lee, S Neidle Nature 417 (6891), 876-880, 2002 | 2343 | 2002 |
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? S Balasubramanian, LH Hurley, S Neidle Nature reviews Drug discovery 10 (4), 261-275, 2011 | 1726 | 2011 |
Nucleic acids in chemistry and biology GM Blackburn Royal Society of Chemistry, 2006 | 1340 | 2006 |
Highly prevalent putative quadruplex sequence motifs in human DNA AK Todd, M Johnston, S Neidle Nucleic acids research 33 (9), 2901-2907, 2005 | 1126 | 2005 |
Inhibition of human telomerase by a G-quadruplex-interactive compound D Sun, B Thompson, BE Cathers, M Salazar, SM Kerwin, JO Trent, ... Journal of medicinal chemistry 40 (14), 2113-2116, 1997 | 1070 | 1997 |
Telomere maintenance as a target for anticancer drug discovery S Neidle, G Parkinson Nature Reviews Drug Discovery 1 (5), 383-393, 2002 | 793 | 2002 |
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function AM Burger, F Dai, CM Schultes, AP Reszka, MJ Moore, JA Double, ... Cancer research 65 (4), 1489-1496, 2005 | 697 | 2005 |
A standard reference frame for the description of nucleic acid base-pair geometry WK Olson, M Bansal, SK Burley, RE Dickerson, M Gerstein, SC Harvey, ... Journal of molecular biology 313 (1), 229-237, 2001 | 692 | 2001 |
Putative DNA Quadruplex Formation within the Human c-kit Oncogene S Rankin, AP Reszka, J Huppert, M Zloh, GN Parkinson, AK Todd, ... Journal of the American Chemical Society 127 (30), 10584-10589, 2005 | 658 | 2005 |
Human telomeric G‐quadruplex: The current status of telomeric G‐quadruplexes as therapeutic targets in human cancer S Neidle The FEBS journal 277 (5), 1118-1125, 2010 | 645 | 2010 |
G-quadruplex nucleic acids as therapeutic targets S Balasubramanian, S Neidle Current opinion in chemical biology 13 (3), 345-353, 2009 | 639 | 2009 |
DNA minor-groove recognition by small molecules S Neidle Natural product reports 18 (3), 291-309, 2001 | 632 | 2001 |
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors M Read, RJ Harrison, B Romagnoli, FA Tanious, SH Gowan, AP Reszka, ... Proceedings of the National Academy of Sciences 98 (9), 4844-4849, 2001 | 608 | 2001 |
The structure of telomeric DNA S Neidle, GN Parkinson Current opinion in structural biology 13 (3), 275-283, 2003 | 572 | 2003 |
Quadruplex nucleic acids as novel therapeutic targets S Neidle Journal of medicinal chemistry 59 (13), 5987-6011, 2016 | 565 | 2016 |
Quadruplex nucleic acids S Neidle, S Balasubramanian Royal Society of Chemistry, 2006 | 554 | 2006 |
Loop-length-dependent folding of G-quadruplexes P Hazel, J Huppert, S Balasubramanian, S Neidle Journal of the American Chemical Society 126 (50), 16405-16415, 2004 | 541 | 2004 |
The structures of quadruplex nucleic acids and their drug complexes S Neidle Current opinion in structural biology 19 (3), 239-250, 2009 | 519 | 2009 |
Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter AT Phan, V Kuryavyi, S Burge, S Neidle, DJ Patel Journal of the American Chemical Society 129 (14), 4386-4392, 2007 | 490 | 2007 |