Post-translational modifications of transporters LC Czuba, KM Hillgren, PW Swaan Pharmacology & therapeutics 192, 88-99, 2018 | 145 | 2018 |
The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal vitamin A homeostasis, but is required for exogenous atRA clearance G Zhong, C Hogarth, JM Snyder, L Palau, T Topping, W Huang, LC Czuba, ... Journal of Biological Chemistry 294 (29), 11166-11179, 2019 | 26 | 2019 |
Gut commensals expand vitamin A metabolic capacity of the mammalian host M Bonakdar, LC Czuba, G Han, G Zhong, H Luong, N Isoherranen, ... Cell host & microbe 30 (8), 1084-1092. e5, 2022 | 23 | 2022 |
Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis LC Czuba, X Wu, W Huang, N Hollingshead, JB Roberto, HL Kenerson, ... Clinical and Translational Science 14 (3), 976-989, 2021 | 20 | 2021 |
Knockout of Cyp26a1 and Cyp26b1 during post-natal life causes reduced lifespan, dermatitis, splenomegaly and systemic inflammation in mice JM Snyder, G Zhong, C Hogarth, W Huang, T Topping, J LaFrance, ... FASEB journal: official publication of the Federation of American Societies …, 2020 | 20 | 2020 |
Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers PP Chothe, LC Czuba, RH Moore, PW Swaan Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (3), 645-653, 2018 | 19 | 2018 |
Mechanistic PBPK modeling of urine pH effect on renal and systemic disposition of methamphetamine and amphetamine W Huang, LC Czuba, N Isoherranen Journal of Pharmacology and Experimental Therapeutics 373 (3), 488-501, 2020 | 15 | 2020 |
Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (SLC10A2) PP Chothe, LC Czuba, EN Ayewoh, PW Swaan Molecular Pharmaceutics 16 (8), 3569-3576, 2019 | 15 | 2019 |
Analysis of vitamin A and retinoids in biological matrices LC Czuba, G Zhong, KC Yabut, N Isoherranen Methods in enzymology 637, 309-340, 2020 | 12 | 2020 |
Plasma retinoid concentrations are altered in pregnant women LC Czuba, EE Fay, J LaFrance, CK Smith, S Shum, SL Moreni, J Mao, ... Nutrients 14 (7), 1365, 2022 | 9 | 2022 |
Infant dextromethorphan and dextrorphan exposure via breast milk from mothers who are CYP2D6 extensive metabolizers S Shum, A Yadav, E Fay, S Moreni, J Mao, L Czuba, C Wang, ... The Journal of Clinical Pharmacology 62 (6), 747-755, 2022 | 7 | 2022 |
Objective identification of cannabis use levels in clinical populations is critical for detecting pharmacological outcomes W Huang, LC Czuba, JA Manuzak, JN Martin, PW Hunt, NR Klatt, ... Cannabis and Cannabinoid Research 7 (6), 852-864, 2022 | 6 | 2022 |
Pregnancy has no clinically significant effect on the pharmacokinetics of bupropion or its metabolites EE Fay, LC Czuba, JE Sager, S Shum, A Stephenson-Famy, ... Therapeutic drug monitoring 43 (6), 780-788, 2021 | 6 | 2021 |
Impact of pregnancy and vitamin A supplementation on CYP2D6 activity OU Amaeze, LC Czuba, AS Yadav, EE Fay, J LaFrance, S Shum, ... The Journal of Clinical Pharmacology 63 (3), 363-372, 2023 | 4 | 2023 |
Temporal changes in the systemic concentrations of retinoids in pregnant and postpartum women H Jeong, AT Armstrong, N Isoherranen, L Czuba, A Yang, K Zumpf, ... PloS one 18 (2), e0280424, 2023 | 4 | 2023 |
S-acylation status of bile acid transporter hASBT regulates its function, metabolic stability, membrane expression, and phosphorylation state EN Ayewoh, LC Czuba, TT Nguyen, PW Swaan Biochimica et Biophysica Acta (BBA)-Biomembranes 1863 (2), 183510, 2021 | 4 | 2021 |
Evidence of depot‐specific regulation of all‐trans‐retinoic acid biosynthesis in human adipose tissue KB Rubinow, G Zhong, LC Czuba, JY Chen, E Williams, Z Parr, ... Clinical and Translational Science 15 (6), 1460-1471, 2022 | 3 | 2022 |
LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1β LC Czuba, N Isoherranen Drug Metabolism and Disposition 52 (5), 442-454, 2024 | | 2024 |
Pharmacokinetics and pharmacodynamics of endogenous and exogenous cortisol in premenopausal, healthy women A Authement, JK Amory, LC Czuba, AS Yadav, J Zhu, KB Rubinow, ... Drug Metabolism and Pharmacokinetics 55, 100803, 2024 | | 2024 |
Effect of isotretinoin on CYP2D6 and CYP3A activity in patients with severe acne Y Zhao, JC Vary Jr, AS Yadav, LC Czuba, S Shum, J LaFrance, W Huang, ... British Journal of Clinical Pharmacology 90 (3), 759-768, 2024 | | 2024 |