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Dr Eleanor Wheeler
Dr Eleanor Wheeler
Associate Principal Scientist, AstraZeneca
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ...
Nature genetics 42 (11), 937-948, 2010
35442010
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105-116, 2010
25402010
Hundreds of variants clustered in genomic loci and biological pathways affect human height
H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ...
Nature 467 (7317), 832-838, 2010
23082010
Common variants near MC4R are associated with fat mass, weight and risk of obesity
RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ...
Nature genetics 40 (6), 768-775, 2008
15772008
The allelic landscape of human blood cell trait variation and links to common complex disease
WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa, AL Mann, D Mead, ...
Cell 167 (5), 1415-1429. e19, 2016
12002016
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, ...
Nature genetics 42 (11), 949-960, 2010
11052010
Variants in MTNR1B influence fasting glucose levels
I Prokopenko, C Langenberg, JC Florez, R Saxena, N Soranzo, ...
Nature genetics 41 (1), 77-81, 2009
9082009
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
AK Manning, MF Hivert, RA Scott, JL Grimsby, N Bouatia-Naji, H Chen, ...
Nature genetics 44 (6), 659-669, 2012
9032012
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
RA Scott, V Lagou, RP Welch, E Wheeler, ME Montasser, J Luan, R Mägi, ...
Nature genetics 44 (9), 991-1005, 2012
8882012
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
SI Berndt, S Gustafsson, R Mägi, A Ganna, E Wheeler, MF Feitosa, ...
Nature genetics 45 (5), 501-512, 2013
7582013
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits
BF Voight, HM Kang, J Ding, CD Palmer, C Sidore, PS Chines, NP Burtt, ...
Public Library of Science 8 (8), e1002793, 2012
6082012
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
LA Lotta, P Gulati, FR Day, F Payne, H Ongen, M Van De Bunt, ...
Nature genetics 49 (1), 17-26, 2017
5362017
Genetic variants influencing circulating lipid levels and risk of coronary artery disease
DM Waterworth, SL Ricketts, K Song, L Chen, JH Zhao, S Ripatti, ...
Arteriosclerosis, thrombosis, and vascular biology 30 (11), 2264-2276, 2010
5092010
A genome-wide association meta-analysis identifies new childhood obesity loci
Nature Genetics 44 (5), 526-31, 2012
502*2012
Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways
N Soranzo, S Sanna, E Wheeler, C Gieger, D Radke, J Dupuis, ...
Diabetes 59 (12), 3229-3239, 2010
4842010
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ...
Diabetes 60 (10), 2624-2634, 2011
4572011
LDL-cholesterol concentrations: a genome-wide association study
MS Sandhu, DM Waterworth, SL Debenham, E Wheeler, K Papadakis, ...
The Lancet 371 (9611), 483-491, 2008
4162008
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
E Wheeler, A Leong, CT Liu, MF Hivert, RJ Strawbridge, C Podmore, M Li, ...
PLoS medicine 14 (9), e1002383, 2017
4132017
The trans-ancestral genomic architecture of glycemic traits
J Chen, CN Spracklen, G Marenne, A Varshney, LJ Corbin, J Luan, ...
Nature genetics 53 (6), 840-860, 2021
4072021
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity
E Wheeler, N Huang, EG Bochukova, JM Keogh, S Lindsay, S Garg, ...
Nature genetics 45 (5), 513-517, 2013
3742013
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