DNA methylation on N6-adenine in mammalian embryonic stem cells TP Wu, T Wang, MG Seetin, Y Lai, S Zhu, K Lin, Y Liu, SD Byrum, ... Nature 532 (7599), 329-333, 2016 | 668 | 2016 |
Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation J Beaulaurier, S Zhu, G Deikus, I Mogno, XS Zhang, A Davis-Richardson, ... Nature Biotechnology, 2017 | 143 | 2017 |
Dysregulation of miRNA-9 in a subset of schizophrenia patient-derived neural progenitor cells A Topol, S Zhu, BJ Hartley, J English, ME Hauberg, N Tran, ... Cell reports 15 (5), 1024-1036, 2016 | 133 | 2016 |
Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes J Beaulaurier, XS Zhang, S Zhu, R Sebra, C Rosenbluh, G Deikus, ... Nature communications 6 (1), 7438, 2015 | 109 | 2015 |
Neuronal impact of patient-specific aberrant NRXN1α splicing E Flaherty, S Zhu, N Barretto, E Cheng, PJM Deans, MB Fernando, ... Nature genetics 51 (12), 1679-1690, 2019 | 107 | 2019 |
Altered WNT signaling in human induced pluripotent stem cell neural progenitor cells derived from four schizophrenia patients A Topol, S Zhu, N Tran, A Simone, G Fang, KJ Brennand Biological psychiatry 78 (6), e29-e34, 2015 | 95 | 2015 |
Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis PH Oliveira, JW Ribis, EM Garrett, D Trzilova, A Kim, O Sekulovic, ... Nature microbiology 5 (1), 166-180, 2020 | 88 | 2020 |
Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing S Zhu, J Beaulaurier, G Deikus, TP Wu, M Strahl, Z Hao, G Luo, ... Genome research 28 (7), 1067-1078, 2018 | 79 | 2018 |
Use of big data in drug development for precision medicine: an update T Qian, S Zhu, Y Hoshida Expert review of precision medicine and drug development 4 (3), 189-200, 2019 | 78 | 2019 |
Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients A Topol, JA English, E Flaherty, P Rajarajan, BJ Hartley, S Gupta, ... Translational psychiatry 5 (10), e662-e662, 2015 | 74 | 2015 |
A blood-based prognostic liver secretome signature and long-term hepatocellular carcinoma risk in advanced liver fibrosis N Fujiwara, M Kobayashi, AJ Fobar, A Hoshida, CA Marquez, B Koneru, ... Med 2 (7), 836-850. e10, 2021 | 53 | 2021 |
Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease N Fujiwara, N Kubota, E Crouchet, B Koneru, CA Marquez, AK Jajoriya, ... Science translational medicine 14 (650), eabo4474, 2022 | 50 | 2022 |
A cytosine methytransferase modulates the cell envelope stress response in the cholera pathogen MC Chao, S Zhu, S Kimura, BM Davis, EE Schadt, G Fang, MK Waldor PLoS genetics 11 (11), e1005666, 2015 | 45 | 2015 |
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease Z Wang, S Zhu, Y Jia, Y Wang, N Kubota, N Fujiwara, R Gordillo, C Lewis, ... Cell 186 (9), 1968-1984. e20, 2023 | 23 | 2023 |
Molecular heterogeneity in hepatocellular carcinoma S Zhu, Y Hoshida Hepatic oncology 5 (1), HEP10, 2018 | 23 | 2018 |
Hidden Markov induced Dynamic Bayesian Network for recovering time evolving gene regulatory networks S Zhu, Y Wang Scientific reports 5 (1), 17841, 2015 | 22 | 2015 |
Molecular signature predictive of long-term liver fibrosis progression to inform antifibrotic drug development T Qian, N Fujiwara, B Koneru, A Ono, N Kubota, AK Jajoriya, MG Tung, ... Gastroenterology 162 (4), 1210-1225, 2022 | 20 | 2022 |
Matrix Epistasis: ultrafast, exhaustive epistasis scan for quantitative traits with covariate adjustment S Zhu, G Fang Bioinformatics, 2018 | 16 | 2018 |
Modeling exon expression using histone modifications S Zhu, G Wang, B Liu, Y Wang PLoS One 8 (6), e67448, 2013 | 16 | 2013 |
Chromatin structure characteristics of pre-miRNA genomic sequences S Zhu, Q Jiang, G Wang, B Liu, M Teng, Y Wang BMC genomics 12, 1-13, 2011 | 16 | 2011 |