Metal complexes in medicine with a focus on enzyme inhibition CM Che, FM Siu Current opinion in chemical biology 14 (2), 255-261, 2010 | 257 | 2010 |
DNA binding and cytotoxicity of ruthenium (II) and rhenium (I) complexes of 2-amino-4-phenylamino-6-(2-pyridyl)-1, 3, 5-triazine DL Ma, CM Che, FM Siu, M Yang, KY Wong Inorganic chemistry 46 (3), 740-749, 2007 | 186 | 2007 |
A dinuclear cyclometalated gold (iii)–phosphine complex targeting thioredoxin reductase inhibits hepatocellular carcinoma in vivo RWY Sun, CN Lok, TTH Fong, CKL Li, ZF Yang, T Zou, AFM Siu, CM Che Chemical Science, 2013 | 116 | 2013 |
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): Induction of endoplasmic reticulum stress and mitochondria‐mediated apoptotic pathways FM Siu, DL Ma, YW Cheung, CN Lok, K Yan, Z Yang, M Yang, SX Xu, ... Proteomics 8 (15), 3105-3117, 2008 | 112 | 2008 |
Cation-π Interactions in Sodiated Phenylalanine Complexes: Is Phenylalanine in the Charge-Solvated or Zwitterionic Form? FM Siu, NL Ma, CW Tsang Journal of the American Chemical Society 123 (14), 3397-3398, 2001 | 79 | 2001 |
Anticancer gold (i)–phosphine complexes as potent autophagy-inducing agents S Tian, FM Siu, SCF Kui, CN Lok, CM Che Chemical Communications 47 (33), 9318-9320, 2011 | 77 | 2011 |
Competition between π and Non‐π Cation‐Binding Sites in Aromatic Amino Acids: A Theoretical Study of Alkali Metal Cation (Li+, Na+, K+)–Phenylalanine Complexes FM Siu, NL Ma, CW Tsang Chemistry-A European Journal 10 (8), 1966-1976, 2004 | 58 | 2004 |
Fluorophore-labeled β-lactamase as a biosensor for β-lactam antibiotics: a study of the biosensing process PH Chan, PK So, DL Ma, Y Zhao, TS Lai, WH Chung, KC Chan, KF Yiu, ... Journal of the American Chemical Society 130 (20), 6351-6361, 2008 | 57 | 2008 |
Fluorophore-Labeled: b-Lactamase as a Biosensor for b-Lactam Antibiolics: A Study of the Bosensing Process PH Chan, PK So, DL Ma, YX Zhao, TS Lai, WH Chung, KC Chan, KF Yiu, ... Journal of the American Chemical Society 46, 740-749, 2008 | 57* | 2008 |
Alkali metal cation-ligand affinities: Basis set superposition correction for the Gaussian protocols FM Siu, NL Ma, CW Tsang The Journal of Chemical Physics 114, 7045, 2001 | 57 | 2001 |
A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma N Wang, Y Feng, M Zhu, FM Siu, KM Ng, CM Che Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 2890-2899, 2013 | 55 | 2013 |
Absolute potassium cation affinities (PCAs) in the gas phase JKC Lau, CHS Wong, PS Ng, FM Siu, NL Ma, CW Tsang Chemistry-A European Journal 9 (14), 3383-3396, 2003 | 53 | 2003 |
Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice C Xu, B Bai, P Fan, Y Cai, B Huang, IKM Law, L Liu, A Xu, C Tung, X Li, ... American journal of translational research 5 (4), 412, 2013 | 51 | 2013 |
An ytterbium (iii) porphyrin induces endoplasmic reticulum stress and apoptosis in cancer cells: cytotoxicity and transcriptomics studies WL Kwong, RWY Sun, CN Lok, FM Siu, SY Wong, KH Low, CM Che Chemical Science 4 (2), 747-754, 2013 | 44 | 2013 |
A theoretical study of potassium cation-glycine (K< sup>+</sup>-Gly) interactions CHS Wong, FM Siu, NL Ma, CW Tsang Journal of Molecular Structure: THEOCHEM 588 (1), 9-16, 2002 | 42 | 2002 |
Anticancer dirhodium (ii, ii) carboxylates as potent inhibitors of ubiquitin-proteasome system FM Siu, IWS Lin, K Yan, CN Lok, KH Low, TYC Leung, TL Lam, CM Che Chemical Science 3 (6), 1785-1793, 2012 | 39 | 2012 |
Highly regio-, diastereo-and enantioselective one-pot gold/chiral Brønsted acid-catalysed cascade synthesis of bioactive diversely substituted tetrahydroquinolines XY Liu, YP Xiao, FM Siu, LC Ni, Y Chen, L Wang, CM Che Organic & Biomolecular Chemistry 10 (35), 7208-7219, 2012 | 39 | 2012 |
Diastereoselective ruthenium porphyrin-catalyzed tandem nitrone formation/1, 3-dipolar cycloaddition for isoxazolidines. Synthesis, in silico docking study and in vitro … AR Reddy, Z Guo, FM Siu, CN Lok, F Liu, KC Yeung, CY Zhou, CM Che Organic & Biomolecular Chemistry 10 (46), 9165-9174, 2012 | 38 | 2012 |
Experimental validation of theoretical potassium and sodium cation affinities of amides by mass spectrometric kinetic method measurements Y Tsang, FM Siu, CS Ho, NL Ma, CW Tsang Rapid communications in mass spectrometry 18 (3), 345-355, 2004 | 35 | 2004 |
Interaction of alkali metal cations and short chain alcohols: effect of core size on theoretical affinities NL Ma, FM Siu, CW Tsang Chemical Physics Letters 322 (1), 65-72, 2000 | 35 | 2000 |