| Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity L Corrales, LH Glickman, SM McWhirter, DB Kanne, KE Sivick, ... Cell reports 11 (7), 1018-1030, 2015 | 1356 | 2015 |
| STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade J Fu, DB Kanne, M Leong, LH Glickman, SM McWhirter, E Lemmens, ... Science translational medicine 7 (283), 283ra52-283ra52, 2015 | 754 | 2015 |
| Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer DT Le, A Wang-Gillam, V Picozzi, TF Greten, T Crocenzi, G Springett, ... Journal of clinical Oncology 33 (12), 1325-1333, 2015 | 660 | 2015 |
| Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity CW Chan, E Crafton, HN Fan, J Flook, K Yoshimura, M Skarica, ... Nature medicine 12 (2), 207-213, 2006 | 543 | 2006 |
| The host STING pathway at the interface of cancer and immunity L Corrales, SM McWhirter, TW Dubensky, TF Gajewski The Journal of clinical investigation 126 (7), 2404-2411, 2016 | 418 | 2016 |
| A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune … DT Le, DG Brockstedt, R Nir-Paz, J Hampl, S Mathur, J Nemunaitis, ... Clinical cancer research 18 (3), 858-868, 2012 | 391 | 2012 |
| Listeria-based cancer vaccines that segregate immunogenicity from toxicity DG Brockstedt, MA Giedlin, ML Leong, KS Bahjat, Y Gao, W Luckett, ... Proceedings of the National Academy of Sciences 101 (38), 13832-13837, 2004 | 361 | 2004 |
| Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways WW Leitner, LN Hwang, MJ Deveer, A Zhou, RH Silverman, BRG Williams, ... Nature medicine 9 (1), 33-39, 2003 | 353 | 2003 |
| Adjuvants for cancer vaccines TW Dubensky Jr, SG Reed Seminars in immunology 22 (3), 155-161, 2010 | 341 | 2010 |
| Magnitude of therapeutic STING activation determines CD8+ T cell-mediated anti-tumor immunity KE Sivick, AL Desbien, LH Glickman, GL Reiner, L Corrales, NH Surh, ... Cell reports 25 (11), 3074-3085. e5, 2018 | 335 | 2018 |
| Eukaryotic layered vector initiation systems TW Dubensky Jr, JM Polo, DJ Jolly, DA Driver US Patent 5,814,482, 1998 | 303 | 1998 |
| Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer TW Dubensky Jr, DA Driver, JM Polo, BA Belli, EM Latham, CE Ibanez, ... Journal of virology 70 (1), 508-519, 1996 | 271 | 1996 |
| DNA immunization against herpes simplex virus: enhanced efficacy using a Sindbis virus-based vector MJ Hariharan, DA Driver, K Townsend, D Brumm, JM Polo, BA Belli, ... Journal of virology 72 (2), 950-958, 1998 | 269 | 1998 |
| VSV-G pseudotyped lentiviral vector particles produced in human cells are inactivated by human serum NJ DePolo, JD Reed, PL Sheridan, K Townsend, SL Sauter, DJ Jolly, ... Molecular Therapy 2 (3), 218-222, 2000 | 265 | 2000 |
| Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells MV Goldberg, CH Maris, EL Hipkiss, AS Flies, L Zhen, RM Tuder, ... Blood, The Journal of the American Society of Hematology 110 (1), 186-192, 2007 | 250 | 2007 |
| Enhancement of tumor-specific immune response with plasmid DNA replicon vectors WW Leitner, H Ying, DA Driver, TW Dubensky, NP Restifo Cancer research 60 (1), 51-55, 2000 | 245 | 2000 |
| Radiotherapy combined with novel STING-targeting oligonucleotides results in regression of established tumors JR Baird, D Friedman, B Cottam, TW Dubensky Jr, DB Kanne, S Bambina, ... Cancer research 76 (1), 50-61, 2016 | 235 | 2016 |
| Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect G Wang, V Slepushkin, J Zabner, S Keshavjee, JC Johnston, SL Sauter, ... The Journal of clinical investigation 104 (11), R55-R62, 1999 | 224 | 1999 |
| An alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector S Perri, CE Greer, K Thudium, B Doe, H Legg, H Liu, RE Romero, Z Tang, ... Journal of virology 77 (19), 10394-10403, 2003 | 221 | 2003 |
| Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants TW Dubensky Jr, DB Kanne, ML Leong Therapeutic advances in vaccines 1 (4), 131-143, 2013 | 208 | 2013 |
