Primary structures of PYY, [Pro34]PYY, and PYY-(3–36) confer different conformations and receptor selectivity DA Keire, P Mannon, M Kobayashi, JH Walsh, TE Solomon, JR Reeve Jr American Journal of Physiology-Gastrointestinal and Liver Physiology 279 (1 …, 2000 | 181 | 2000 |
Kinetics and equilibria of thiol/disulfide interchange reactions of selected biological thiols and related molecules with oxidized glutathione DA Keire, E Strauss, W Guo, B Noszal, DL Rabenstein The Journal of Organic Chemistry 57 (1), 123-127, 1992 | 164 | 1992 |
Daily, intermittent intravenous infusion of peptide YY (3-36) reduces daily food intake and adiposity in rats PK Chelikani, AC Haver, JR Reeve Jr, DA Keire, RD Reidelberger American Journal of Physiology-Regulatory, Integrative and Comparative …, 2006 | 135 | 2006 |
Structure and receptor binding of PYY analogs DA Keire, CW Bowers, TE Solomon, JR Reeve Jr Peptides 23 (2), 305-321, 2002 | 134 | 2002 |
The US regulatory and pharmacopeia response to the global heparin contamination crisis AY Szajek, E Chess, K Johansen, G Gratzl, E Gray, D Keire, RJ Linhardt, ... Nature biotechnology 34 (6), 625-630, 2016 | 117 | 2016 |
A retrospective evaluation of the use of mass spectrometry in FDA biologics license applications S Rogstad, A Faustino, A Ruth, D Keire, M Boyne, J Park Journal of the American Society for Mass Spectrometry 28 (5), 786-794, 2016 | 112 | 2016 |
CCK-58 is the only detectable endocrine form of cholecystokinin in rat JR Reeve Jr, GM Green, P Chew, VE Eysselein, DA Keire American Journal of Physiology-Gastrointestinal and Liver Physiology 285 (2 …, 2003 | 111 | 2003 |
Mechanism and energetics for complexation of 90Y with 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid (DOTA), a model for cancer radioimmunotherapy YH Jang, M Blanco, S Dasgupta, DA Keire, JE Shively, WA Goddard Journal of the American Chemical Society 121 (26), 6142-6151, 1999 | 105 | 1999 |
The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides A Stengel, D Keire, M Goebel, L Evilevitch, B Wiggins, Y Tache, ... Endocrinology 150 (11), 5113-5118, 2009 | 96 | 2009 |
Solution Structure of Monomeric Peptide YY Supports the Functional Significance of the PP-Fold, DA Keire, M Kobayashi, TE Solomon, JR Reeve Biochemistry 39 (32), 9935-9942, 2000 | 91 | 2000 |
Analysis of crude heparin by 1H NMR, capillary electrophoresis, and strong-anion-exchange-HPLC for contamination by over sulfated chondroitin sulfate DA Keire, ML Trehy, JC Reepmeyer, RE Kolinski, W Ye, J Dunn, ... Journal of pharmaceutical and biomedical analysis 51 (4), 921-926, 2010 | 81 | 2010 |
Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics RG Brinson, JP Marino, F Delaglio, LW Arbogast, RM Evans, A Kearsley, ... MAbs 11 (1), 94-105, 2019 | 75 | 2019 |
Diversifying the global heparin supply chain: reintroduction of bovine heparin in the United States? A Szajek, E Gray, D Keire, B Mulloy, A Al-Hakim, C Chase, MDLC Soares, ... Pharmaceutical Technology 39 (11), 2015 | 69 | 2015 |
The conformation of substance P in lipid environments DA Keire, TG Fletcher Biophysical journal 70 (4), 1716-1727, 1996 | 69 | 1996 |
Precision and robustness of 2D-NMR for structure assessment of filgrastim biosimilars H Ghasriani, DJ Hodgson, RG Brinson, I McEwen, LF Buhse, S Kozlowski, ... Nature biotechnology 34 (2), 139-141, 2016 | 68 | 2016 |
The interaction of β‐amyloid protein fragment (12‐28) with lipid environments TG Fletcher, DA Keire Protein science 6 (3), 666-675, 1997 | 68 | 1997 |
Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry B Wang, AC Gucinski, DA Keire, LF Buhse, MT Boyne II Analyst 138 (10), 3058-3065, 2013 | 58 | 2013 |
Characterization of currently marketed heparin products: reversed-phase ion-pairing liquid chromatography mass spectrometry of heparin digests AM Brustkern, LF Buhse, M Nasr, A Al-Hakim, DA Keire Analytical chemistry 82 (23), 9865-9870, 2010 | 56 | 2010 |
A Cautionary Tale: Quantitative LC-HRMS Analytical Procedures for the Analysis of N-Nitrosodimethylamine in Metformin J Yang, W Ye, CD Sommers, JD Rodriguez, DA Keire The AAPS Journal 22, 1-8, 2020 | 54 | 2020 |
Quantitative chemical analysis by NMR DL Rabenstein, DA Keire Modern NMR techniques and their application in chemistry, 1991 | 53 | 1991 |