Mechanisms for DNA charge transport JC Genereux, JK Barton Chemical reviews 110 (3), 1642-1662, 2010 | 862 | 2010 |
Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments MD Shoulders, LM Ryno, JC Genereux, JJ Moresco, PG Tu, C Wu, ... Cell reports 3 (4), 1279-1292, 2013 | 551 | 2013 |
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation L Plate, CB Cooley, JJ Chen, RJ Paxman, CM Gallagher, F Madoux, ... elife 5, e15550, 2016 | 215 | 2016 |
DNA-mediated charge transport in redox sensing and signaling JC Genereux, AK Boal, JK Barton Journal of the American Chemical Society 132 (3), 891-905, 2010 | 209 | 2010 |
Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation TK Rainbolt, N Atanassova, JC Genereux, RL Wiseman Cell metabolism 18 (6), 908-919, 2013 | 188 | 2013 |
Redox signaling between DNA repair proteins for efficient lesion detection AK Boal, JC Genereux, PA Sontz, JA Gralnick, DK Newman, JK Barton Proceedings of the National Academy of Sciences 106 (36), 15237-15242, 2009 | 156 | 2009 |
Unfolded protein response‐induced ER dj3 secretion links ER stress to extracellular proteostasis JC Genereux, S Qu, M Zhou, LM Ryno, S Wang, MD Shoulders, ... The EMBO journal 34 (1), 4-19, 2015 | 145 | 2015 |
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans A Baranczak, Y Liu, S Connelly, WGH Du, ER Greiner, JC Genereux, ... Journal of the American Chemical Society 137 (23), 7404-7414, 2015 | 104 | 2015 |
Single-step charge transport through DNA over long distances JC Genereux, SM Wuerth, JK Barton Journal of the American Chemical Society 133 (11), 3863-3868, 2011 | 89 | 2011 |
Distance-independent DNA charge transport across an adenine tract KE Augustyn, JC Genereux, JK Barton ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH- 46 (30), 5731, 2007 | 89 | 2007 |
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher’s disease YL Tan, JC Genereux, S Pankow, JMFG Aerts, JR Yates, JW Kelly Chemistry & biology 21 (8), 967-976, 2014 | 83 | 2014 |
ATF6 activation reduces the secretion and extracellular aggregation of destabilized variants of an amyloidogenic protein JJ Chen, JC Genereux, S Qu, JD Hulleman, MD Shoulders, RL Wiseman Chemistry & biology 21 (11), 1564-1574, 2014 | 71 | 2014 |
Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1 LM Ryno, JC Genereux, T Naito, RI Morimoto, ET Powers, MD Shoulders, ... ACS chemical biology 9 (6), 1273-1283, 2014 | 64 | 2014 |
Ping-pong electron transfer through DNA B Elias, JC Genereux, JK Barton Angewandte Chemie (International ed. in English) 47 (47), 9067, 2008 | 61 | 2008 |
XBP1s activation can globally remodel N-glycan structure distribution patterns MY Wong, K Chen, A Antonopoulos, BT Kasper, MB Dewal, RJ Taylor, ... Proceedings of the National Academy of Sciences 115 (43), E10089-E10098, 2018 | 55 | 2018 |
Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis A Leung, SK Nah, W Reid, A Ebata, CM Koch, S Monti, JC Genereux, ... Stem cell reports 1 (5), 451-463, 2013 | 51 | 2013 |
Back-electron transfer suppresses the periodic length dependence of DNA-mediated charge transport across adenine tracts JC Genereux, KE Augustyn, ML Davis, F Shao, JK Barton Journal of the American Chemical Society 130 (45), 15150-15156, 2008 | 42 | 2008 |
Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis EH Suh, Y Liu, S Connelly, JC Genereux, IA Wilson, JW Kelly Journal of the American Chemical Society 135 (47), 17869-17880, 2013 | 38 | 2013 |
Endoplasmic reticulum proteostasis influences the oligomeric state of an amyloidogenic protein secreted from mammalian cells JJ Chen, JC Genereux, EH Suh, VF Vartabedian, B Rius, S Qu, ... Cell chemical biology 23 (10), 1282-1293, 2016 | 36 | 2016 |
Formation kinetics of insulin-based amyloid gels and the effect of added metalloporphyrins RF Pasternack, EJ Gibbs, S Sibley, L Woodard, P Hutchinson, J Genereux, ... Biophysical Journal 90 (3), 1033-1042, 2006 | 35 | 2006 |