| Tissue-Specific Oncogenic Activity of KRASA146T EJ Poulin, AK Bera, J Lu, YJ Lin, SD Strasser, JA Paulo, TQ Huang, ... Cancer discovery 9 (6), 738-755, 2019 | 151* | 2019 |
| The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects CW Johnson, D Reid, JA Parker, S Salter, R Knihtila, P Kuzmic, C Mattos Journal of Biological Chemistry 292 (31), 12981-12993, 2017 | 131 | 2017 |
| Isoform-specific destabilization of the active site reveals a molecular mechanism of intrinsic activation of KRas G13D CW Johnson, YJ Lin, D Reid, J Parker, S Pavlopoulos, P Dischinger, ... Cell reports 28 (6), 1538-1550. e7, 2019 | 75 | 2019 |
| Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention C Johnson, DL Burkhart, KM Haigis Cancer discovery 12 (4), 913-923, 2022 | 50 | 2022 |
| Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding PY Ting, CW Johnson, C Fang, X Cao, TG Graeber, C Mattos, J Colicelli The FASEB Journal 29 (9), 3750, 2015 | 50 | 2015 |
| DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site BM Kearney, CW Johnson, DM Roberts, P Swartz, C Mattos Journal of molecular biology 426 (3), 611-629, 2014 | 47 | 2014 |
| The allosteric switch and conformational states in Ras GTPase affected by small molecules CW Johnson, C Mattos The enzymes 33, 41-67, 2013 | 36 | 2013 |
| Expression, purification, crystallization and X-ray data collection for RAS and its mutants CW Johnson, G Buhrman, PY Ting, J Colicelli, C Mattos Data in brief 6, 423-427, 2016 | 15 | 2016 |
| Regulation of GTPase function by autophosphorylation CW Johnson, HS Seo, EM Terrell, MH Yang, F KleinJan, T Gebregiworgis, ... Molecular cell 82 (5), 950-968. e14, 2022 | 13 | 2022 |
| Allosteric regulation of switch-II domain controls KRAS oncogenicity MH Yang, TH Tran, B Hunt, R Agnor, CW Johnson, B Shui, TJ Waybright, ... Cancer research 83 (19), 3176-3183, 2023 | 4 | 2023 |
| Allosteric communication in the activity of Ras GTPases CW Johnson Northeastern University, 2015 | 2 | 2015 |
| All Roads Lead to Rome: YAP/TAZ Activity Influences Efficacy of KRASG12C Inhibitors CW Johnson, KM Haigis Cancer Research 83 (24), 4005-4007, 2023 | 1 | 2023 |
| Crystal structures of acetylated HRas K104 mimic K104Q and mutant K104A suggest unique role of K104 in interlobe communication across HRas K Marcus, C Johnson, J Sanchez, C Mattos The FASEB Journal 30, 1116.2-1116.2, 2016 | 1 | 2016 |
| Allosteric site variants affect GTP hydrolysis on RAS CW Johnson, SK Fetics, KP Davis, JA Rodrigues, C Mattos Protein Science 32 (10), e4767, 2023 | | 2023 |
Matt R. SteensmaVan Andel Research Institute在 vai.org 的电子邮件经过验证
