Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents GL Beretta, G Cassinelli, M Pennati, V Zuco, L Gatti European journal of medicinal chemistry 142, 271-289, 2017 | 212 | 2017 |
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity S Dallavalle, A Ferrari, B Biasotti, L Merlini, S Penco, G Gallo, M Marzi, ... Journal of medicinal chemistry 44 (20), 3264-3274, 2001 | 143 | 2001 |
Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin GL Beretta, V Benedetti, G Cossa, YGA Assaraf, E Bram, L Gatti, E Corna, ... Biochemical pharmacology 79 (8), 1108-1117, 2010 | 122 | 2010 |
Current status and perspectives in the development of camptothecins F Zunino, S Dallavalle, D Laccabue, G Beretta, L Merlini, G Pratesi Current pharmaceutical design 8 (27), 2505-2520, 2002 | 121 | 2002 |
Camptothecin resistance in cancer: insights into the molecular mechanisms of a DNA-damaging drug G L Beretta, L Gatti, P Perego, N Zaffaroni Current medicinal chemistry 20 (12), 1541-1565, 2013 | 115 | 2013 |
Role of proliferation in HER2 status predicted response to doxorubicin M Campiglio, G Somenzi, C Olgiati, G Beretta, A Balsari, N Zaffaroni, ... International journal of cancer 105 (4), 568-573, 2003 | 103 | 2003 |
Molecular mechanisms of anthracycline activity GL Beretta, F Zunino Anthracycline Chemistry and Biology II: Mode of action, clinical aspects and …, 2008 | 102 | 2008 |
miR-875-5p counteracts epithelial-to-mesenchymal transition and enhances radiation response in prostate cancer through repression of the EGFR-ZEB1 axis R El Bezawy, D Cominetti, N Fenderico, V Zuco, GL Beretta, M Dugo, ... Cancer letters 395, 53-62, 2017 | 94 | 2017 |
Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and-resistant cells GL Beretta, L Gatti, S Tinelli, E Corna, D Colangelo, F Zunino, P Perego Biochemical pharmacology 68 (2), 283-291, 2004 | 85 | 2004 |
Mechanisms of cellular resistance to camptothecins GL Beretta, P Perego, F Zunino Current medicinal chemistry 13 (27), 3291-3305, 2006 | 83 | 2006 |
Gimatecan, a novel camptothecin with a promising preclinical profile G Pratesi, GL Beretta, F Zunino Anti-cancer drugs 15 (6), 545-552, 2004 | 81 | 2004 |
Atomic force microscopy study of DNA conformation in the presence of drugs V Cassina, D Seruggia, GL Beretta, D Salerno, D Brogioli, S Manzini, ... European Biophysics Journal 40, 59-68, 2011 | 77 | 2011 |
Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment GL Beretta, G Cossa, L Gatti, F Zunino, P Perego Current medicinal chemistry 17 (15), 1500-1508, 2010 | 72 | 2010 |
Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors GL Beretta, P Perego, F Zunino Expert opinion on therapeutic targets 12 (10), 1243-1256, 2008 | 71 | 2008 |
Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs D Salerno, D Brogioli, V Cassina, D Turchi, GL Beretta, D Seruggia, ... Nucleic acids research 38 (20), 7089-7099, 2010 | 70 | 2010 |
Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma M Bagnoli, GL Beretta, L Gatti, S Pilotti, P Alberti, E Tarantino, ... BioMed research international 2013 (1), 143202, 2013 | 69 | 2013 |
ABC transporters as potential targets for modulation of drug resistance. L Gatti, GL Beretta, G Cossa, F Zunino, P Perego Mini reviews in medicinal chemistry 9 (9), 1102-1112, 2009 | 68 | 2009 |
Pain in women: a perspective review on a relevant clinical issue that deserves prioritization R Casale, F Atzeni, L Bazzichi, G Beretta, E Costantini, P Sacerdote, ... Pain and Therapy 10, 287-314, 2021 | 67 | 2021 |
Synthesis and cytotoxic activity of polyamine analogues of camptothecin S Dallavalle, G Giannini, D Alloatti, A Casati, E Marastoni, L Musso, ... Journal of medicinal chemistry 49 (17), 5177-5186, 2006 | 67 | 2006 |
Synthesis and cytotoxic activity of substituted luotonin A derivatives S Dallavalle, L Merlini, GL Beretta, S Tinelli, F Zunino Bioorganic & medicinal chemistry letters 14 (23), 5757-5761, 2004 | 67 | 2004 |