A four-step cycle driven by PI (4) P hydrolysis directs sterol/PI (4) P exchange by the ER-Golgi tether OSBP B Mesmin, J Bigay, JM Von Filseck, S Lacas-Gervais, G Drin, B Antonny Cell 155 (4), 830-843, 2013 | 747 | 2013 |
Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity J Bigay, B Antonny Developmental cell 23 (5), 886-895, 2012 | 560 | 2012 |
Fluoroaluminates activate transducin-GDP by mimicking the γ-phosphate of GTP in its binding site JE Bigay, P Deterre, C Pfister, M Chabre FEBS letters 191 (2), 181-185, 1985 | 536 | 1985 |
Fluoride complexes of aluminium or beryllium act on G‐proteins as reversibly bound analogues of the gamma phosphate of GTP. J Bigay, P Deterre, C Pfister, M Chabre The EMBO Journal 6 (10), 2907-2913, 1987 | 500 | 1987 |
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif J Bigay, JF Casella, G Drin, B Mesmin, B Antonny The EMBO journal 24 (13), 2244-2253, 2005 | 442 | 2005 |
Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature J Bigay, P Gounon, S Robineau, B Antonny Nature 426 (6966), 563-566, 2003 | 408 | 2003 |
cGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunits. P Deterre, J Bigay, F Forquet, M Robert, M Chabre Proceedings of the National Academy of Sciences 85 (8), 2424-2428, 1988 | 296 | 1988 |
Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein JRPM Strating, L van der Linden, L Albulescu, J Bigay, M Arita, L Delang, ... Cell reports 10 (4), 600-615, 2015 | 247 | 2015 |
α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding IM Pranke, V Morello, J Bigay, K Gibson, JM Verbavatz, B Antonny, ... Journal of Cell Biology 194 (1), 89-103, 2011 | 226 | 2011 |
Role of protein-phospholipid interactions in the activation of ARF1 by the guanine nucleotide exchange factor Arno S Paris, S Béraud-Dufour, S Robineau, J Bigay, B Antonny, M Chabre, ... Journal of Biological Chemistry 272 (35), 22221-22226, 1997 | 210 | 1997 |
Sterol transfer, PI 4P consumption, and control of membrane lipid order by endogenous OSBP B Mesmin, J Bigay, J Polidori, D Jamecna, S Lacas‐Gervais, B Antonny The EMBO Journal 36 (21), 3156-3174, 2017 | 200 | 2017 |
Heterologous multimeric assembly is essential for K+ channel activity of neuronal and cardiac G-protein-activated inward rectifiers F Duprat, F Lesage, E Guillemare, M Fink, JP Hugnot, J Bigay, ... Biochemical and biophysical research communications 212 (2), 657-663, 1995 | 171 | 1995 |
The oxysterol-binding protein cycle: burning off PI (4) P to transport cholesterol B Antonny, J Bigay, B Mesmin Annual review of biochemistry 87 (1), 809-837, 2018 | 144 | 2018 |
Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature B Mesmin, G Drin, S Levi, M Rawet, D Cassel, J Bigay, B Antonny Biochemistry 46 (7), 1779-1790, 2007 | 136 | 2007 |
Activation of retinal rod cyclic GMP‐phosphodiesterase by transducin: Characterization of the complex formed by phosphodiesterase inhibitor and transducin α‐subunit P Deterre, J Bigay, M Robert, C Pfister, H Kühn, M Chabre Proteins: Structure, Function, and Bioinformatics 1 (2), 188-193, 1986 | 113 | 1986 |
Roles of lipid modifications of transducin subunits in their GDP-dependent association and membrane binding J Bigay, E Faurobert, M Franco, M Chabre Biochemistry 33 (47), 14081-14090, 1994 | 111 | 1994 |
The mechanism of aluminum-independent G-protein activation by fluoride and magnesium. 31P NMR spectroscopy and fluorescence kinetic studies. B Antonny, M Sukumar, J Bigay, M Chabre, T Higashijima Journal of Biological Chemistry 268 (4), 2393-2402, 1993 | 72 | 1993 |
Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307 L Albulescu, J Bigay, B Biswas, M Weber-Boyvat, CM Dorobantu, ... Antiviral Research 140, 37-44, 2017 | 55 | 2017 |
Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation B Antonny, J Bigay, JF Casella, G Drin, B Mesmin, P Gounon Biochemical Society Transactions 33 (4), 619-622, 2005 | 54 | 2005 |
An intrinsically disordered region in OSBP acts as an entropic barrier to control protein dynamics and orientation at membrane contact sites D Jamecna, J Polidori, B Mesmin, M Dezi, D Levy, J Bigay, B Antonny Developmental Cell 49 (2), 220-234. e8, 2019 | 51 | 2019 |