Functionally defined therapeutic targets in diffuse intrinsic pontine glioma CS Grasso, Y Tang, N Truffaux, NE Berlow, L Liu, MA Debily, MJ Quist, ... Nature medicine 21 (6), 555-559, 2015 | 653 | 2015 |
Induction and down-regulation of Sox17 and its possible roles during the course of gastrointestinal tumorigenesis YC Du, H Oshima, K Oguma, T Kitamura, H Itadani, T Fujimura, YS Piao, ... Gastroenterology 137 (4), 1346-1357, 2009 | 88 | 2009 |
A C19MC-LIN28A-MYCN oncogenic circuit driven by hijacked super-enhancers is a distinct therapeutic vulnerability in ETMRs: a lethal brain tumor P Sin-Chan, I Mumal, T Suwal, B Ho, X Fan, I Singh, Y Du, M Lu, N Patel, ... Cancer cell 36 (1), 51-67. e7, 2019 | 87 | 2019 |
Systems biology–based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma L Huang, S Garrett Injac, K Cui, F Braun, Q Lin, Y Du, H Zhang, M Kogiso, ... Science translational medicine 10 (464), eaat0150, 2018 | 67 | 2018 |
Prostaglandin E2, Wnt, and BMP in gastric tumor mouse models H Oshima, K Oguma, YC Du, M Oshima Cancer science 100 (10), 1779-1785, 2009 | 64 | 2009 |
The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy H Wang, YC Du, X Zhou, H Liu, SC Tang Cancer and Metastasis Reviews 33, 173-181, 2014 | 57 | 2014 |
Functional precision medicine identifies new therapeutic candidates for medulloblastoma JM Rusert, EF Juarez, S Brabetz, J Jensen, A Garancher, LQ Chau, ... Cancer research 80 (23), 5393-5407, 2020 | 50 | 2020 |
RETRACTED ARTICLE: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma A Garancher, H Suzuki, S Haricharan, LQ Chau, MB Masihi, JM Rusert, ... Nature neuroscience 23 (7), 842-853, 2020 | 38 | 2020 |
Platelet-type 12-lipoxygenase accelerates tumor promotion of mouse epidermal cells through enhancement of cloning efficiency YS Piao, YC Du, H Oshima, JC Jin, M Nomura, T Yoshimoto, M Oshima Carcinogenesis 29 (2), 440-447, 2008 | 37 | 2008 |
Fusion of CpG‐ODN‐stimulating dendritic cells with Lewis lung cancer cells can enhance anti‐tumor immune responses YC Du, P Lin, J Zhang, YR Lu, QZ Ning, Q Wang Tissue Antigens 67 (5), 368-376, 2006 | 33 | 2006 |
Concurrent inhibition of neurosphere and monolayer cells of pediatric glioblastoma by Aurora A inhibitor MLN8237 predicted survival extension in PDOX models M Kogiso, L Qi, FK Braun, SG Injac, L Zhang, Y Du, H Zhang, FY Lin, ... Clinical Cancer Research 24 (9), 2159-2170, 2018 | 31 | 2018 |
Patient-derived orthotopic xenograft (PDOX) mouse models of primary and recurrent meningioma H Zhang, L Qi, Y Du, LF Huang, FK Braun, M Kogiso, Y Zhao, C Li, ... Cancers 12 (6), 1478, 2020 | 28 | 2020 |
Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse … M Kogiso, L Qi, H Lindsay, Y Huang, X Zhao, Z Liu, FK Braun, Y Du, ... Oncotarget 8 (50), 87455, 2017 | 27 | 2017 |
IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma NE Berlow, MN Svalina, MJ Quist, TP Settelmeyer, V Zherebitskiy, ... PloS one 13 (4), e0193565, 2018 | 26 | 2018 |
Spatial dissection of invasive front from tumor mass enables discovery of novel microRNA drivers of glioblastoma invasion Y Huang, L Qi, M Kogiso, Y Du, FK Braun, H Zhang, LF Huang, S Xiao, ... Advanced Science 8 (23), 2101923, 2021 | 18 | 2021 |
Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors L Qi, M Kogiso, Y Du, H Zhang, FK Braun, Y Huang, WY Teo, H Lindsay, ... Cancer letters 493, 197-206, 2020 | 16 | 2020 |
Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma H Lindsay, Y Huang, Y Du, FK Braun, WY Teo, M Kogiso, L Qi, H Zhang, ... Journal of neuro-oncology 128, 47-56, 2016 | 14 | 2016 |
Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas S Zhao, J Li, H Zhang, L Qi, Y Du, M Kogiso, FK Braun, S Xiao, Y Huang, ... Nature communications 13 (1), 6689, 2022 | 13 | 2022 |
Evaluation of an EZH2 inhibitor in patient-derived orthotopic xenograft models of pediatric brain tumors alone and in combination with chemo-and radiation therapies L Qi, H Lindsay, M Kogiso, Y Du, FK Braun, H Zhang, L Guo, S Zhao, ... Laboratory Investigation 102 (2), 185-193, 2022 | 13 | 2022 |
Systems biology-based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma. Sci. Transl. Med. 10https L Huang, S Garrett Injac, K Cui, F Braun, Q Lin, Y Du, H Zhang, M Kogiso, ... doi. org/10.1126/scitranslmed. aat0150, 2018 | 10 | 2018 |