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Mohammad Abdel-Halim
Mohammad Abdel-Halim
Prof. of Pharmaceutical Chemistry, German University in Cairo
在 guc.edu.eg 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
In Vitro transdermal delivery of sesamol using oleic acid chemically-modified gelatin nanoparticles as a potential breast cancer medication
SR ElMasry, RM Hathout, M Abdel-Halim, S Mansour
Journal of Drug Delivery Science and Technology 48, 30-39, 2018
572018
Molecularly imprinted polymers for selective extraction of rosmarinic acid from Rosmarinus officinalis L.
EM Saad, NA El Gohary, M Abdel-Halim, H Handoussa, RM El Nashar, ...
Food chemistry 335, 127644, 2021
552021
Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective
AH Abadi, BD Gary, HN Tinsley, GA Piazza, M Abdel-Halim
European journal of medicinal chemistry 45 (4), 1278-1286, 2010
502010
Prevention of hepatic stellate cell activation using JQ1-and atorvastatin-loaded chitosan nanoparticles as a promising approach in therapy of liver fibrosis
R Hassan, SN Tammam, S El Safy, M Abdel-Halim, A Asimakopoulou, ...
European Journal of Pharmaceutics and Biopharmaceutics 134, 96-106, 2019
472019
Development of selective Clk1 and-4 inhibitors for cellular depletion of cancer-relevant proteins
AK ElHady, M Abdel-Halim, AH Abadi, M Engel
Journal of Medicinal Chemistry 60 (13), 5377-5391, 2017
472017
Discovery and optimization of 1, 3, 5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-ζ
M Abdel-Halim, B Diesel, AK Kiemer, AH Abadi, RW Hartmann, M Engel
Journal of medicinal chemistry 57 (15), 6513-6530, 2014
382014
Natural products repertoire of the Red Sea
EM El-Hossary, M Abdel-Halim, ES Ibrahim, SM Pimentel-Elardo, ...
Marine Drugs 18 (9), 457, 2020
292020
Collagenase loaded chitosan nanoparticles for digestion of the collagenous scar in liver fibrosis: The effect of chitosan intrinsic collagen binding on the success of targeting
S El-Safy, SN Tammam, M Abdel-Halim, ME Ali, J Youshia, ...
European Journal of Pharmaceutics and Biopharmaceutics 148, 54-66, 2020
272020
Synthesis and antimicrobial evaluation of new halogenated 1, 3-Thiazolidin-4-ones
SG Hammad, MG El-Gazzar, NS Abutaleb, D Li, I Ramming, A Shekhar, ...
Bioorganic chemistry 95, 103517, 2020
242020
Taurine loaded chitosan-pectin nanoparticle shows curative effect against acetic acid-induced colitis in rats
O Ahmed, M Abdel-Halim, A Farid, A Elamir
Chemico-Biological Interactions 351, 109715, 2022
222022
Potential neuroprotective activity of Mentha longifolia L. in aluminum chloride‐induced rat model of Alzheimer’s disease
S Elshamy, A Abdel Motaal, M Abdel‐Halim, D Medhat, H Handoussa
Journal of Food Biochemistry 45 (4), 1770, 2021
222021
Development of novel 2, 4-bispyridyl thiophene–based compounds as highly potent and selective Dyrk1A inhibitors. Part I: benzamide and benzylamide derivatives
SS Darwish, M Abdel-Halim, M Salah, AH Abadi, W Becker, M Engel
European Journal of Medicinal Chemistry 157, 1031-1050, 2018
222018
Computational design of molecularly imprinted polymer for solid phase extraction of moxifloxacin hydrochloride from Avalox® tablets and spiked human urine samples
MA Hammam, M Abdel-Halim, A Madbouly, HA Wagdy, RM El Nashar
Microchemical Journal 148, 51-56, 2019
192019
Development of novel amide–derivatized 2, 4-bispyridyl thiophenes as highly potent and selective Dyrk1A inhibitors. Part II: Identification of the cyclopropylamide moiety as a …
SS Darwish, M Abdel-Halim, AK ElHady, M Salah, AH Abadi, W Becker, ...
European Journal of Medicinal Chemistry 158, 270-285, 2018
192018
Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer’s disease
DE Hafez, M Dubiel, G La Spada, M Catto, D Reiner-Link, YT Syu, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2175821, 2023
162023
An overview of cdc2‐like kinase 1 (Clk1) inhibitors and their therapeutic indications
AK ElHady, DS El‐Gamil, AH Abadi, M Abdel‐Halim, M Engel
Medicinal Research Reviews 43 (2), 343-398, 2023
162023
Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors
AK ElHady, SP Shih, YC Chen, YC Liu, NS Ahmed, AB Keeton, GA Piazza, ...
Bioorganic chemistry 98, 103742, 2020
152020
Pharmacological inhibition of protein kinase C (PKC) ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD)
M Abdel-Halim, SS Darwish, AK ElHady, J Hoppstädter, AH Abadi, ...
European Journal of Pharmaceutical Sciences 93, 405-409, 2016
152016
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects
YT AlNajjar, M Gabr, AK ElHady, M Salah, G Wilms, AH Abadi, W Becker, ...
European Journal of Medicinal Chemistry 227, 113911, 2022
142022
From celecoxib to a novel class of phosphodiesterase 5 inhibitors: Trisubstituted pyrazolines as novel phosphodiesterase 5 inhibitors with extremely high potency and …
M Abdel-Halim, S Sigler, NAS Racheed, A Hefnawy, RK Fathalla, ...
Journal of Medicinal Chemistry 64 (8), 4462-4477, 2021
142021
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