In Vitro transdermal delivery of sesamol using oleic acid chemically-modified gelatin nanoparticles as a potential breast cancer medication SR ElMasry, RM Hathout, M Abdel-Halim, S Mansour Journal of Drug Delivery Science and Technology 48, 30-39, 2018 | 57 | 2018 |
Molecularly imprinted polymers for selective extraction of rosmarinic acid from Rosmarinus officinalis L. EM Saad, NA El Gohary, M Abdel-Halim, H Handoussa, RM El Nashar, ... Food chemistry 335, 127644, 2021 | 55 | 2021 |
Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective AH Abadi, BD Gary, HN Tinsley, GA Piazza, M Abdel-Halim European journal of medicinal chemistry 45 (4), 1278-1286, 2010 | 50 | 2010 |
Prevention of hepatic stellate cell activation using JQ1-and atorvastatin-loaded chitosan nanoparticles as a promising approach in therapy of liver fibrosis R Hassan, SN Tammam, S El Safy, M Abdel-Halim, A Asimakopoulou, ... European Journal of Pharmaceutics and Biopharmaceutics 134, 96-106, 2019 | 47 | 2019 |
Development of selective Clk1 and-4 inhibitors for cellular depletion of cancer-relevant proteins AK ElHady, M Abdel-Halim, AH Abadi, M Engel Journal of Medicinal Chemistry 60 (13), 5377-5391, 2017 | 47 | 2017 |
Discovery and optimization of 1, 3, 5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-ζ M Abdel-Halim, B Diesel, AK Kiemer, AH Abadi, RW Hartmann, M Engel Journal of medicinal chemistry 57 (15), 6513-6530, 2014 | 38 | 2014 |
Natural products repertoire of the Red Sea EM El-Hossary, M Abdel-Halim, ES Ibrahim, SM Pimentel-Elardo, ... Marine Drugs 18 (9), 457, 2020 | 29 | 2020 |
Collagenase loaded chitosan nanoparticles for digestion of the collagenous scar in liver fibrosis: The effect of chitosan intrinsic collagen binding on the success of targeting S El-Safy, SN Tammam, M Abdel-Halim, ME Ali, J Youshia, ... European Journal of Pharmaceutics and Biopharmaceutics 148, 54-66, 2020 | 27 | 2020 |
Synthesis and antimicrobial evaluation of new halogenated 1, 3-Thiazolidin-4-ones SG Hammad, MG El-Gazzar, NS Abutaleb, D Li, I Ramming, A Shekhar, ... Bioorganic chemistry 95, 103517, 2020 | 24 | 2020 |
Taurine loaded chitosan-pectin nanoparticle shows curative effect against acetic acid-induced colitis in rats O Ahmed, M Abdel-Halim, A Farid, A Elamir Chemico-Biological Interactions 351, 109715, 2022 | 22 | 2022 |
Potential neuroprotective activity of Mentha longifolia L. in aluminum chloride‐induced rat model of Alzheimer’s disease S Elshamy, A Abdel Motaal, M Abdel‐Halim, D Medhat, H Handoussa Journal of Food Biochemistry 45 (4), 1770, 2021 | 22 | 2021 |
Development of novel 2, 4-bispyridyl thiophene–based compounds as highly potent and selective Dyrk1A inhibitors. Part I: benzamide and benzylamide derivatives SS Darwish, M Abdel-Halim, M Salah, AH Abadi, W Becker, M Engel European Journal of Medicinal Chemistry 157, 1031-1050, 2018 | 22 | 2018 |
Computational design of molecularly imprinted polymer for solid phase extraction of moxifloxacin hydrochloride from Avalox® tablets and spiked human urine samples MA Hammam, M Abdel-Halim, A Madbouly, HA Wagdy, RM El Nashar Microchemical Journal 148, 51-56, 2019 | 19 | 2019 |
Development of novel amide–derivatized 2, 4-bispyridyl thiophenes as highly potent and selective Dyrk1A inhibitors. Part II: Identification of the cyclopropylamide moiety as a … SS Darwish, M Abdel-Halim, AK ElHady, M Salah, AH Abadi, W Becker, ... European Journal of Medicinal Chemistry 158, 270-285, 2018 | 19 | 2018 |
Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer’s disease DE Hafez, M Dubiel, G La Spada, M Catto, D Reiner-Link, YT Syu, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2175821, 2023 | 16 | 2023 |
An overview of cdc2‐like kinase 1 (Clk1) inhibitors and their therapeutic indications AK ElHady, DS El‐Gamil, AH Abadi, M Abdel‐Halim, M Engel Medicinal Research Reviews 43 (2), 343-398, 2023 | 16 | 2023 |
Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors AK ElHady, SP Shih, YC Chen, YC Liu, NS Ahmed, AB Keeton, GA Piazza, ... Bioorganic chemistry 98, 103742, 2020 | 15 | 2020 |
Pharmacological inhibition of protein kinase C (PKC) ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) M Abdel-Halim, SS Darwish, AK ElHady, J Hoppstädter, AH Abadi, ... European Journal of Pharmaceutical Sciences 93, 405-409, 2016 | 15 | 2016 |
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects YT AlNajjar, M Gabr, AK ElHady, M Salah, G Wilms, AH Abadi, W Becker, ... European Journal of Medicinal Chemistry 227, 113911, 2022 | 14 | 2022 |
From celecoxib to a novel class of phosphodiesterase 5 inhibitors: Trisubstituted pyrazolines as novel phosphodiesterase 5 inhibitors with extremely high potency and … M Abdel-Halim, S Sigler, NAS Racheed, A Hefnawy, RK Fathalla, ... Journal of Medicinal Chemistry 64 (8), 4462-4477, 2021 | 14 | 2021 |