| Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials NA Hanania, P Korenblat, KR Chapman, ED Bateman, P Kopecky, ... The Lancet Respiratory Medicine 4 (10), 781-796, 2016 | 472 | 2016 |
| Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies NA Hanania, M Noonan, J Corren, P Korenblat, Y Zheng, SK Fischer, ... Thorax 70 (8), 748-756, 2015 | 420 | 2015 |
| SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP) D Vucic, K Deshayes, H Ackerly, MT Pisabarro, S Kadkhodayan, ... Journal of biological chemistry 277 (14), 12275-12279, 2002 | 334 | 2002 |
| Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP D Vucic, MC Franklin, HJA Wallweber, K Das, BP Eckelman, H Shin, ... Biochemical Journal 385 (1), 11-20, 2005 | 253 | 2005 |
| Uncoupling oxygen transfer and electron transfer in the oxygenation of camphor analogues by cytochrome P450-cam: direct observation of an intermolecular isotope effect for … S Kadkhodayan, ED Coulter, DM Maryniak, TA Bryson, JH Dawson Journal of Biological Chemistry 270 (47), 28042-28048, 1995 | 145 | 1995 |
| Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP) MC Franklin, S Kadkhodayan, H Ackerly, D Alexandru, MD Distefano, ... Biochemistry 42 (27), 8223-8231, 2003 | 134 | 2003 |
| Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1 D Kirchhofer, M Peek, W Li, J Stamos, C Eigenbrot, S Kadkhodayan, ... Journal of Biological Chemistry 278 (38), 36341-36349, 2003 | 123 | 2003 |
| Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity B Segelke, M Knapp, S Kadkhodayan, R Balhorn, B Rupp Proceedings of the National Academy of Sciences 101 (18), 6888-6893, 2004 | 120 | 2004 |
| Emerging technologies to increase ligand binding assay sensitivity SK Fischer, A Joyce, M Spengler, TY Yang, Y Zhuang, MS Fjording, ... The AAPS journal 17, 93-101, 2015 | 99 | 2015 |
| Specific immune response to phospholipase B-like 2 protein, a host cell impurity in lebrikizumab clinical material SK Fischer, M Cheu, K Peng, J Lowe, J Araujo, E Murray, D McClintock, ... The AAPS journal 19, 254-263, 2017 | 93 | 2017 |
| Establishment of neurofilament light chain Simoa assay in cerebrospinal fluid and blood R Hendricks, D Baker, J Brumm, T Davancaze, C Harp, A Herman, ... Bioanalysis 11 (15), 1405-1418, 2019 | 86 | 2019 |
| Rapid identification of small binding motifs with high-throughput phage display: discovery of peptidic antagonists of IGF-1 function K Deshayes, ML Schaffer, NJ Skelton, GR Nakamura, S Kadkhodayan, ... Chemistry & biology 9 (4), 495-505, 2002 | 82 | 2002 |
| Evaluating the use of antibody variable region (Fv) charge as a risk assessment tool for predicting typical cynomolgus monkey pharmacokinetics DB Yadav, VK Sharma, CA Boswell, I Hotzel, D Tesar, Y Shang, Y Ying, ... Journal of Biological Chemistry 290 (50), 29732-29741, 2015 | 75 | 2015 |
| Translational pharmacokinetics and pharmacodynamics of an FcRn‐variant anti‐CD4 monoclonal antibody from preclinical model to phase I study Y Zheng, H Scheerens, JC Davis Jr, R Deng, SK Fischer, C Woods, ... Clinical Pharmacology & Therapeutics 89 (2), 283-290, 2011 | 56 | 2011 |
| A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo AG Olivero, C Eigenbrot, R Goldsmith, K Robarge, DR Artis, J Flygare, ... Journal of Biological Chemistry 280 (10), 9160-9169, 2005 | 56 | 2005 |
| 2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3–LBA: immunogenicity, biomarkers and PK … S Gupta, S Richards, L Amaravadi, S Piccoli, B Desilva, R Pillutla, ... Bioanalysis 9 (24), 1967-1996, 2017 | 55 | 2017 |
| Firestein & kelley’s textbook of rheumatology-E-book GS Firestein, RC Budd, SE Gabriel, IB McInnes, JR O'Dell Elsevier Health Sciences, 2020 | 52 | 2020 |
| Use of quantitative pharmacology in the development of HAE1, a high-affinity anti-IgE monoclonal antibody WS Putnam, J Li, J Haggstrom, C Ng, S Kadkhodayan-Fischer, M Cheu, ... The AAPS journal 10, 425-430, 2008 | 51 | 2008 |
| Cloning, expression, and one-step purification of the minimal essential domain of the light chain of botulinum neurotoxin type A S Kadkhodayan, MS Knapp, JJ Schmidt, SE Fabes, B Rupp, R Balhorn Protein Expression and Purification 19 (1), 125-130, 2000 | 50 | 2000 |
| 2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3–LBA/cell-based assays: immunogenicity … L Stevenson, S Richards, R Pillutla, A Torri, J Kamerud, D Mehta, S Keller, ... Bioanalysis 10 (24), 1973-2001, 2018 | 49 | 2018 |
