PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene N Rahman, S Seal, D Thompson, P Kelly, A Renwick, A Elliott, S Reid, ... Nature genetics 39 (2), 165-167, 2007 | 1186 | 2007 |
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles A Renwick, D Thompson, S Seal, P Kelly, T Chagtai, M Ahmed, B North, ... Nature genetics 38 (8), 873-875, 2006 | 859 | 2006 |
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles S Seal, D Thompson, A Renwick, A Elliott, P Kelly, R Barfoot, T Chagtai, ... Nature genetics 38 (11), 1239-1241, 2006 | 854 | 2006 |
Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors J Wegert, N Ishaque, R Vardapour, C Geörg, Z Gu, M Bieg, B Ziegler, ... Cancer cell 27 (2), 298-311, 2015 | 318 | 2015 |
Gain of 1q as a prognostic biomarker in Wilms tumors (WTs) treated with preoperative chemotherapy in the International Society of Paediatric Oncology (SIOP) WT 2001 trial: a … T Chagtai, C Zill, L Dainese, J Wegert, S Savola, S Popov, W Mifsud, ... Journal of Clinical Oncology 34 (26), 3195-3203, 2016 | 129 | 2016 |
Multiple mechanisms of MYCN dysregulation in Wilms tumour RD Williams, T Chagtai, M Alcaide-German, J Apps, J Wegert, S Popov, ... Oncotarget 6 (9), 7232, 2015 | 115 | 2015 |
TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia M Maschietto, RD Williams, T Chagtai, SD Popov, NJ Sebire, G Vujanic, ... PloS one 9 (10), e109924, 2014 | 105 | 2014 |
Subtype-Specific FBXW7 Mutation and MYCN Copy Number Gain in Wilms' Tumor RD Williams, R Al-Saadi, T Chagtai, S Popov, B Messahel, N Sebire, ... Clinical Cancer Research 16 (7), 2036-2045, 2010 | 92 | 2010 |
Intra-tumor genetic heterogeneity in Wilms tumor: clonal evolution and clinical implications GD Cresswell, JR Apps, T Chagtai, B Mifsud, CC Bentley, M Maschietto, ... EBioMedicine 9, 120-129, 2016 | 77 | 2016 |
Molecular profiling reveals frequent gain of MYCN and anaplasia‐specific loss of 4q and 14q in wilms tumor RD Williams, R Al‐Saadi, R Natrajan, A Mackay, T Chagtai, S Little, ... Genes, Chromosomes and Cancer 50 (12), 982-995, 2011 | 75 | 2011 |
Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour J Charlton, RD Williams, NJ Sebire, S Popov, G Vujanic, T Chagtai, ... Genome medicine 7, 1-11, 2015 | 55 | 2015 |
Breast Cancer Susceptibility Collaboration (UK), Easton DF, Stratton MR (2007) PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene N Rahman, S Seal, D Thompson, P Kelly, A Renwick, A Elliott, S Reid, ... Nat Genet 39 (2), 165-167, 0 | 41 | |
Breast Cancer Susceptibility Collaboration (UK): Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles S Seal, D Thompson, A Renwick, A Elliott, P Kelly, R Barfoot, T Chagtai, ... Nat Genet 38 (11), 1239-1241, 2006 | 39 | 2006 |
Somatic TP53 mutations are detectable in circulating tumor DNA from children with anaplastic Wilms tumors TD Treger, T Chagtai, R Butcher, GD Cresswell, R Al-Saadi, J Brok, ... Translational Oncology 11 (6), 1301-1306, 2018 | 25 | 2018 |
Bilateral Wilms Tumor with TP53-Related Anaplasia SD Popov, GM Vujanic, NJ Sebire, T Chagtai, R Williams, S Vaidya, ... Pediatric and Developmental Pathology 16 (3), 217-223, 2013 | 17 | 2013 |
The presence of Y674/Y675 phosphorylated NTRK1 via TP53 repression of PTPN6 expression as a potential prognostic marker in neuroblastoma G Youssef, C Gillett, D Rampling, T Chagtai, A Virasami, J Barton, ... Human Pathology 86, 182-192, 2019 | 7 | 2019 |
Gain of 1q as a biomarker in pre-treated Wilms tumour in the SIOP WT 2001 trial: a SIOP renal tumours biology consortium study T Chagtai, C Zill, L Dainese, R Williams, J Wegert, M Maschietto, ... PEDIATRIC BLOOD & CANCER 61, S114-S114, 2014 | 3 | 2014 |
Somatic TP53 Mutations are Detectable in Circulating Tumour DNA from Children with Anaplastic Wilms Tumours T Treger, T Chagtai, R Butcher, G Cresswell, R Al-Saadi, C Roberts, ... PEDIATRIC BLOOD & CANCER 65, S306-S306, 2018 | | 2018 |
Insights from the Evolutionary Trajectories of Wilms Tumor G Cresswell, T Chagtai, R Al-Saadi, T Treger, R Williams, NM Luscombe, ... PEDIATRIC BLOOD & CANCER 64, S7-S7, 2017 | | 2017 |
256 Integrated analysis of DNA methylation, copy number and expression data in Wilms Tumour identifies subtype-specific molecular signatures J Charlton, M Alcaide-German, T Chagtai, S Popov, N Sebire, M Gessler, ... European Journal of Cancer 3 (51), S45, 2015 | | 2015 |