Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection S Balachandran, PC Roberts, LE Brown, H Truong, AK Pattnaik, ... Immunity 13 (1), 129-141, 2000 | 655 | 2000 |
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes N Grandvaux, MJ Servant, B tenOever, GC Sen, S Balachandran, ... Journal of virology 76 (11), 5532-5539, 2002 | 538 | 2002 |
Activation of the dsRNA‐dependent protein kinase, PKR, induces apoptosis through FADD‐mediated death signaling S Balachandran, CN Kim, WC Yeh, TW Mak, K Bhalla, GN Barber The EMBO journal, 1998 | 491 | 1998 |
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway S Balachandran, PC Roberts, T Kipperman, KN Bhalla, RW Compans, ... Journal of virology 74 (3), 1513-1523, 2000 | 401 | 2000 |
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases RJ Thapa, S Nogusa, P Chen, JL Maki, A Lerro, M Andrake, GF Rall, ... Proceedings of the National Academy of Sciences 110 (33), E3109-E3118, 2013 | 375 | 2013 |
A FADD-dependent innate immune mechanism in mammalian cells S Balachandran, E Thomas, GN Barber Nature 432 (7015), 401-405, 2004 | 362 | 2004 |
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ... Nature communications 11 (1), 4938, 2020 | 358 | 2020 |
DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death RJ Thapa, JP Ingram, KB Ragan, S Nogusa, DF Boyd, AA Benitez, ... Cell host & microbe 20 (5), 674-681, 2016 | 357 | 2016 |
RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus S Nogusa, RJ Thapa, CP Dillon, S Liedmann, TH Oguin, JP Ingram, ... Cell host & microbe 20 (1), 13-24, 2016 | 353 | 2016 |
Influenza virus Z-RNAs induce ZBP1-mediated necroptosis T Zhang, C Yin, DF Boyd, G Quarato, JP Ingram, M Shubina, KB Ragan, ... Cell 180 (6), 1115-1129. e13, 2020 | 337 | 2020 |
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition WJ Kaiser, LP Daley-Bauer, RJ Thapa, P Mandal, SB Berger, C Huang, ... Proceedings of the National Academy of Sciences 111 (21), 7753-7758, 2014 | 305 | 2014 |
RIPK1 and RIPK3 kinases promote cell-death-independent inflammation by toll-like receptor 4 M Najjar, D Saleh, M Zelic, S Nogusa, S Shah, A Tai, JN Finger, ... Immunity 45 (1), 46-59, 2016 | 283 | 2016 |
Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells D Olagnier, S Peri, C Steel, N van Montfoort, C Chiang, V Beljanski, ... PLoS pathogens 10 (12), e1004566, 2014 | 250 | 2014 |
Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis S Balachandran, M Porosnicu, GN Barber Journal of virology 75 (7), 3474-3479, 2001 | 246 | 2001 |
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming D Olagnier, AM Brandtoft, C Gunderstofte, NL Villadsen, C Krapp, ... Nature communications 9 (1), 3506, 2018 | 229 | 2018 |
Defective translational control facilitates vesicular stomatitis virus oncolysis S Balachandran, GN Barber Cancer cell 5 (1), 51-65, 2004 | 228 | 2004 |
Vesicular stomatitis virus (VSV) therapy of tumors S Balachandran, GN Barber IUBMB life 50 (2), 135-138, 2000 | 212 | 2000 |
The IRF-3 transcription factor mediates Sendai virus-induced apoptosis C Heylbroeck, S Balachandran, MJ Servant, C DeLuca, GN Barber, R Lin, ... Journal of virology 74 (8), 3781-3792, 2000 | 197 | 2000 |
Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent … A Pataer, SA Vorburger, GN Barber, S Chada, AM Mhashilkar, ... Cancer research 62 (8), 2239-2243, 2002 | 186 | 2002 |
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis T Zhang, C Yin, A Fedorov, L Qiao, H Bao, N Beknazarov, S Wang, ... Nature 606 (7914), 594-602, 2022 | 183 | 2022 |