| TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1 A Amadi-Obi, CR Yu, X Liu, RM Mahdi, GL Clarke, RB Nussenblatt, I Gery, ... Nature medicine 13 (6), 711-718, 2007 | 991 | 2007 |
| Interleukin-35 induces regulatory B cells that suppress autoimmune disease RX Wang, CR Yu, IM Dambuza, RM Mahdi, MB Dolinska, YV Sergeev, ... Nature medicine 20 (6), 633-641, 2014 | 770 | 2014 |
| Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance CE Egwuagu, CR Yu, M Zhang, RM Mahdi, SJ Kim, I Gery The Journal of Immunology 168 (7), 3181-3187, 2002 | 589 | 2002 |
| Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases X Liu, YS Lee, CR Yu, CE Egwuagu The Journal of Immunology 180 (9), 6070-6076, 2008 | 323 | 2008 |
| JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response LH Wang, RA Kirken, RA Erwin, CR Yu, WL Farrar The Journal of Immunology 162 (7), 3897-3904, 1999 | 212 | 1999 |
| Dendritic cell maturation requires STAT1 and is under feedback regulation by suppressors of cytokine signaling SH Jackson, CR Yu, RM Mahdi, S Ebong, CE Egwuagu The Journal of Immunology 172 (4), 2307-2315, 2004 | 206 | 2004 |
| IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease IM Dambuza, C He, JK Choi, CR Yu, R Wang, MJ Mattapallil, PT Wingfield, ... Nature communications 8 (1), 719, 2017 | 175 | 2017 |
| Suppressor of cytokine signaling 3 regulates proliferation and activation of T-helper cells CR Yu, RM Mahdi, S Ebong, BP Vistica, I Gery, CE Egwuagu Journal of Biological Chemistry 278 (32), 29752-29759, 2003 | 167 | 2003 |
| IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells F D'Anna, A Yamauchi, CR Yu, JA Horvath-Arcidiacono, ET Bloom Cellular immunology 165 (1), 33-43, 1995 | 131 | 1995 |
| STAT3 protein promotes T-cell survival and inhibits interleukin-2 production through up-regulation of Class O Forkhead transcription factors HM Oh, CR Yu, N Golestaneh, A Amadi-Obi, YS Lee, A Eseonu, ... Journal of Biological Chemistry 286 (35), 30888-30897, 2011 | 130 | 2011 |
| Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and … CR Yu, JX Lin, DW Fink, S Akira, ET Bloom, A Yamauchi Journal of immunology (Baltimore, Md.: 1950) 157 (1), 126-137, 1996 | 125 | 1996 |
| STAT3 protein interacts with Class O Forkhead transcription factors in the cytoplasm and regulates nuclear/cytoplasmic localization of FoxO1 and FoxO3a proteins in CD4+ T cells HM Oh, CR Yu, I Dambuza, B Marrero, CE Egwuagu Journal of Biological Chemistry 287 (36), 30436-30443, 2012 | 107 | 2012 |
| Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin‐27 and interleukin‐10 YS Lee, A Amadi‐Obi, CR Yu, CE Egwuagu Immunology 132 (4), 492-502, 2011 | 106 | 2011 |
| Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals MK Evans, CR Yu, A Lohani, RM Mahdi, X Liu, AR Trzeciak, CE Egwuagu Oncogene 26 (13), 1941-1948, 2007 | 104 | 2007 |
| Novel IL27p28/IL12p40 cytokine suppressed experimental autoimmune uveitis by inhibiting autoreactive Th1/Th17 cells and promoting expansion of regulatory T cells RX Wang, CR Yu, RM Mahdi, CE Egwuagu Journal of Biological Chemistry 287 (43), 36012-36021, 2012 | 102 | 2012 |
| Interleukin 35: Critical regulator of immunity and lymphocyte-mediated diseases CE Egwuagu, CR Yu, L Sun, R Wang Cytokine & growth factor reviews 26 (5), 587-593, 2015 | 101 | 2015 |
| Cell proliferation and STAT6 pathways are negatively regulated in T cells by STAT1 and suppressors of cytokine signaling CR Yu, RM Mahdi, S Ebong, BP Vistica, J Chen, Y Guo, I Gery, ... The Journal of Immunology 173 (2), 737-746, 2004 | 97 | 2004 |
| Role of a STAT binding site in the regulation of the human perforin promoter CR Yu, JR Ortaldo, RE Curiel, HA Young, SK Anderson, P Gosselin The Journal of Immunology 162 (5), 2785-2790, 1999 | 96 | 1999 |
| STAT3 activates miR-155 in Th17 cells and acts in concert to promote experimental autoimmune uveitis T Escobar, CR Yu, SA Muljo, CE Egwuagu Investigative ophthalmology & visual science 54 (6), 4017-4025, 2013 | 94 | 2013 |
| Roles for CXC chemokine ligands 10 and 11 in recruiting CD4+ T cells to HIV-1-infected monocyte-derived macrophages, dendritic cells, and lymph nodes JF Foley, CR Yu, R Solow, M Yacobucci, KWC Peden, JM Farber The Journal of Immunology 174 (8), 4892-4900, 2005 | 87 | 2005 |
