Cerebrotendinous xanthomatosis: a comprehensive review of pathogenesis, clinical manifestations, diagnosis, and management S Nie, G Chen, X Cao, Y Zhang Orphanet journal of rare diseases 9, 1-11, 2014 | 325 | 2014 |
Initiation of Parkinson’s disease from gut to brain by δ-secretase EH Ahn, SS Kang, X Liu, G Chen, Z Zhang, B Chandrasekharan, AM Alam, ... Cell research 30 (1), 70-87, 2020 | 81 | 2020 |
Small molecule TrkB agonist deoxygedunin protects nigrostriatal dopaminergic neurons from 6-OHDA and MPTP induced neurotoxicity in rodents S Nie, Y Xu, G Chen, K Ma, C Han, Z Guo, Z Zhang, K Ye, X Cao Neuropharmacology 99, 448-458, 2015 | 66 | 2015 |
Tau accelerates α-synuclein aggregation and spreading in Parkinson’s disease L Pan, C Li, L Meng, Y Tian, M He, X Yuan, G Zhang, Z Zhang, J Xiong, ... Brain 145 (10), 3454-3471, 2022 | 63 | 2022 |
7, 8‐Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone‐Induced Neurotoxicity in Rodents S Nie, K Ma, M Sun, M Lee, Y Tan, G Chen, Z Zhang, Z Zhang, X Cao Parkinson’s Disease 2019 (1), 9193534, 2019 | 37 | 2019 |
Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer’s disease pathologies G Chen, SS Kang, Z Wang, EH Ahn, Y Xia, X Liu, IM Sandoval, ... Science advances 7 (16), eabe4499, 2021 | 27 | 2021 |
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer’s disease G Zhang, L Meng, Z Wang, Q Peng, G Chen, J Xiong, Z Zhang Molecular Neurodegeneration 17 (1), 12, 2022 | 24 | 2022 |
Antidyskinetic effects of MEK inhibitor are associated with multiple neurochemical alterations in the striatum of hemiparkinsonian rats G Chen, S Nie, C Han, K Ma, Y Xu, Z Zhang, SM Papa, X Cao Frontiers in neuroscience 11, 112, 2017 | 22 | 2017 |
TRH analog, taltirelin protects dopaminergic neurons from neurotoxicity of MPTP and rotenone C Zheng, G Chen, Y Tan, W Zeng, Q Peng, J Wang, C Cheng, X Yang, ... Frontiers in Cellular Neuroscience 12, 485, 2018 | 21 | 2018 |
Distinct anti-dyskinetic effects of amantadine and group II metabotropic glutamate receptor agonist LY354740 in a rodent model: An electrophysiological perspective C Zheng, Y Xu, G Chen, Y Tan, W Zeng, J Wang, C Cheng, X Yang, S Nie, ... Neurobiology of Disease 139, 104807, 2020 | 17 | 2020 |
Levetiracetam ameliorates L‐DOPA‐Induced dyskinesia in hemiparkinsonian rats inducing critical molecular changes in the striatum H Du, S Nie, G Chen, K Ma, Y Xu, Z Zhang, SM Papa, X Cao Parkinson’s Disease 2015 (1), 253878, 2015 | 15 | 2015 |
N‐homocysteinylation of α‐synuclein promotes its aggregation and neurotoxicity L Zhou, T Guo, L Meng, X Zhang, Y Tian, L Dai, X Niu, Y Li, C Liu, G Chen, ... Aging Cell 22 (3), e13745, 2023 | 14 | 2023 |
Involvement of p38 mitogen‐activated protein kinase in altered expressions of AQP1 and AQP4 after carbon monoxide poisoning in rat astrocytes J Li, M Jia, G Chen, S Nie, C Zheng, W Zeng, Y Xu, C Wang, X Cao, Q Liu Basic & Clinical Pharmacology & Toxicology 125 (4), 394-404, 2019 | 14 | 2019 |
TRH analog, taltirelin improves motor function of hemi-PD rats without inducing dyskinesia via sustained dopamine stimulating effect C Zheng, G Chen, Y Tan, W Zeng, Q Peng, J Wang, C Cheng, X Yang, ... Frontiers in Cellular Neuroscience 12, 417, 2018 | 14 | 2018 |
UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease G Chen, EH Ahn, SS Kang, Y Xia, X Liu, Z Zhang, K Ye Advanced Science 9 (7), 2103396, 2022 | 12 | 2022 |
Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction X Zhang, L Zou, L Meng, M Xiong, L Pan, G Chen, Y Zheng, J Xiong, ... Elife 10, e65301, 2021 | 12 | 2021 |
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease L Zou, X Zhang, M Xiong, L Meng, Y Tian, L Pan, X Yuan, G Chen, ... Neurobiology of Disease 154, 105326, 2021 | 11 | 2021 |
A synapsin Ⅰ cleavage fragment contributes to synaptic dysfunction in Alzheimer's disease L Meng, L Zou, M Xiong, J Chen, X Zhang, T Yu, Y Li, C Liu, G Chen, ... Aging Cell 21 (5), e13619, 2022 | 10 | 2022 |
Cofilin 1 promotes the aggregation and cell-to-cell transmission of α-synuclein in Parkinson’s disease M Yan, L Meng, L Dai, X Zhang, G Chen, Y Zheng, Y Zha, Y Zeng, ... Biochemical and Biophysical Research Communications 529 (4), 1053-1060, 2020 | 10 | 2020 |
C/EBPβ/AEP signaling couples atherosclerosis to the pathogenesis of Alzheimer’s disease J Liao, G Chen, X Liu, ZZ Wei, SP Yu, Q Chen, K Ye Molecular psychiatry 27 (7), 3034-3046, 2022 | 9 | 2022 |