| Discovery of stimulation-responsive immune enhancers with CRISPR activation DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ... Nature 549 (7670), 111-115, 2017 | 285 | 2017 |
| Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors HS Bandukwala, J Gagnon, S Togher, JA Greenbaum, ED Lamperti, ... Proceedings of the National Academy of Sciences 109 (36), 14532-14537, 2012 | 223 | 2012 |
| Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells TB Sundberg, HG Choi, JH Song, CN Russell, MM Hussain, DB Graham, ... Proceedings of the National Academy of Sciences 111 (34), 12468-12473, 2014 | 97 | 2014 |
| miR-15/16 restrain memory T cell differentiation, cell cycle, and survival JD Gagnon, R Kageyama, HM Shehata, MS Fassett, DJ Mar, EJ Wigton, ... Cell reports 28 (8), 2169-2181. e4, 2019 | 70 | 2019 |
| The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells B Khor, JD Gagnon, G Goel, MI Roche, KL Conway, K Tran, LN Aldrich, ... Elife 4, e05920, 2015 | 63 | 2015 |
| A massively parallel 3′ UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization AJ Litterman, R Kageyama, O Le Tonqueze, W Zhao, JD Gagnon, ... Genome research 29 (6), 896-906, 2019 | 45 | 2019 |
| Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells MJ Benson, T Äijö, X Chang, J Gagnon, UJ Pape, V Anantharaman, ... Proceedings of the National Academy of Sciences 109 (40), 16252-16257, 2012 | 44 | 2012 |
| Female bias for enlarged male body and dorsal fins in Xiphophorus variatus RD MacLaren, J Gagnon, R He Behavioural processes 87 (2), 197-202, 2011 | 26 | 2011 |
| Distinct tissue-specific roles for the disease-associated autophagy genes ATG16L2 and ATG16L1 B Khor, KL Conway, AS Omar, M Biton, AL Haber, N Rogel, LA Baxt, ... The Journal of Immunology 203 (7), 1820-1829, 2019 | 25 | 2019 |
| MicroRNA regulation of CD8+ T cell responses JD Gagnon, KM Ansel Non-coding RNA investigation 3, 2019 | 20 | 2019 |
| The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation BD Wheeler, JD Gagnon, WS Zhu, P Muñoz-Sandoval, SK Wong, ... Elife 12, RP87900, 2023 | 5 | 2023 |
| Tumor cell-adipocyte gap junctions activate lipolysis and are essential for breast tumorigenesis R Camarda, J Williams, S Malkov, LJ Zimmerman, S Manning, D Aran, ... bioRxiv, 277939, 2018 | 5 | 2018 |
| An essential role for miR-15/16 in Treg suppression and restriction of proliferation K Johansson, JD Gagnon, SK Zhou, MS Fassett, AW Schroeder, ... Cell reports 42 (10), 2023 | 4 | 2023 |
| Forced expression of the non-coding RNA miR-17∼ 92 restores activation and function in CD28-deficient CD4+ T cells M Dölz, M Hasiuk, JD Gagnon, M Kornete, R Marone, G Bantug, ... Iscience 25 (11), 2022 | 4 | 2022 |
| The non-coding RNA miR-17~ 92 is a central mediator of T cell activation M Dölz, JD Gagnon, M Kornete, R Marone, G Bantug, R Kageyama, ... BioRxiv, 2020.10. 13.336537, 2020 | 2 | 2020 |
| Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ... Nature 559 (7715), E13-E13, 2018 | 1 | 2018 |
| Pooled CRISPR screening coupled with single-cell sequencing identifies modifiers of CAR T cell state in the context of chronic antigen stimulation S Joshi, G Wozniak, J Gagnon, K Vucci, A Merrell, M Simon, C Oh, ... Cancer Research 84 (6_Supplement), 7034-7034, 2024 | | 2024 |
| COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER USING A TGFßRII ENGINEERED T CELL THERAPY JD Gagnon, B Sennino, S Mandl-Cashman, K Jacoby, W Lu, MM Dubreuil, ... US Patent App. 18/319,743, 2024 | | 2024 |
| Immune cells having co-expressed shrnas and logic gate systems J Williams, M Nguyen, A Yao, S Santoro, A Cooper, J Gagnon, ... US Patent App. 18/311,856, 2023 | | 2023 |
| Multiplexed shRNA cassettes targeting orthogonal pathways (FAS/PTPN2/TGFBR) enhance the potency of integrated circuit T cells (ICTs) in multiple solid tumor models TJ Gardner, A Litterman, BK Singh, L Silva, M Hari, S Zhou, C Tang, ... Cancer Research 83 (7_Supplement), 1768-1768, 2023 | | 2023 |
Anjana RaoHarvard Medical School在 lji.org 的电子邮件经过验证
