Bile acids activated receptors regulate innate immunity S Fiorucci, M Biagioli, A Zampella, E Distrutti Frontiers in immunology 9, 1853, 2018 | 413 | 2018 |
The bile acid receptor GPBAR1 regulates the M1/M2 phenotype of intestinal macrophages and activation of GPBAR1 rescues mice from murine colitis M Biagioli, A Carino, S Cipriani, D Francisci, S Marchianò, P Scarpelli, ... The Journal of Immunology 199 (2), 718-733, 2017 | 231 | 2017 |
Bile acids and their receptors in metabolic disorders S Fiorucci, E Distrutti, A Carino, A Zampella, M Biagioli Progress in Lipid Research 82, 101094, 2021 | 150 | 2021 |
Bile acid signaling in inflammatory bowel diseases S Fiorucci, A Carino, M Baldoni, L Santucci, E Costanzi, L Graziosi, ... Digestive Diseases and Sciences 66, 674-693, 2021 | 145 | 2021 |
GILZ promotes production of peripherally induced Treg cells and mediates the crosstalk between glucocorticoids and TGF-β signaling O Bereshchenko, M Coppo, S Bruscoli, M Biagioli, M Cimino, ... Cell reports 7 (2), 464-475, 2014 | 135 | 2014 |
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis A Carino, S Cipriani, S Marchianò, M Biagioli, C Santorelli, A Donini, ... Scientific Reports 7 (1), 42801, 2017 | 117 | 2017 |
Hijacking SARS-CoV-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on the receptor binding domain A Carino, F Moraca, B Fiorillo, S Marchianò, V Sepe, M Biagioli, ... Frontiers in Chemistry 8, 572885, 2020 | 103 | 2020 |
Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH) S Fiorucci, M Biagioli, V Sepe, A Zampella, E Distrutti Expert Opinion on Investigational Drugs 29 (6), 623-632, 2020 | 84 | 2020 |
Future trends in the treatment of non-alcoholic steatohepatitis S Fiorucci, M Biagioli, E Distrutti Pharmacological research 134, 289-298, 2018 | 61 | 2018 |
Bile acids activated receptors in inflammatory bowel disease M Biagioli, S Marchianò, A Carino, C Di Giorgio, L Santucci, E Distrutti, ... Cells 10 (6), 1281, 2021 | 59 | 2021 |
Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice S Bruscoli, M Biagioli, D Sorcini, T Frammartino, M Cimino, P Sportoletti, ... Blood, The Journal of the American Society of Hematology 126 (15), 1790-1801, 2015 | 57 | 2015 |
Metabolic variability of a multispecies probiotic preparation impacts on the anti-inflammatory activity M Biagioli, L Laghi, A Carino, S Cipriani, E Distrutti, S Marchianò, ... Frontiers in pharmacology 8, 505, 2017 | 51 | 2017 |
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis A Carino, S Marchiano, M Biagioli, M Bucci, V Vellecco, V Brancaleone, ... The FASEB Journal 33 (2), 2809-2822, 2019 | 50 | 2019 |
Signaling from intestine to the host: how bile acids regulate intestinal and liver immunity M Biagioli, A Carino Bile Acids and Their Receptors, 95-108, 2019 | 48 | 2019 |
Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice A Carino, S Cipriani, S Marchianò, M Biagioli, P Scarpelli, A Zampella, ... Scientific reports 7 (1), 13689, 2017 | 47 | 2017 |
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH A Carino, M Biagioli, S Marchianò, C Fiorucci, A Zampella, MC Monti, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 44 | 2019 |
GPBAR1 functions as gatekeeper for liver NKT cells and provides counterregulatory signals in mouse models of immune-mediated hepatitis M Biagioli, A Carino, C Fiorucci, S Marchianò, C Di Giorgio, R Roselli, ... Cellular and Molecular Gastroenterology and Hepatology 8 (3), 447-473, 2019 | 44 | 2019 |
Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders S Fiorucci, M Baldoni, P Ricci, A Zampella, E Distrutti, M Biagioli Current Opinion in Pharmacology 53, 45-54, 2020 | 42 | 2020 |
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis A Carino, M Biagioli, S Marchianò, C Fiorucci, M Bordoni, R Roselli, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 31 | 2020 |
The bile acid receptor GPBAR1 modulates CCL2/CCR2 signaling at the liver sinusoidal/macrophage interface and reverses acetaminophen-induced liver toxicity M Biagioli, A Carino, C Fiorucci, S Marchianò, C Di Giorgio, M Bordoni, ... The Journal of Immunology 204 (9), 2535-2551, 2020 | 30 | 2020 |