Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad3 A Blokzijl, C Dahlqvist, E Reissmann, A Falk, A Moliner, U Lendahl, ... The Journal of cell biology 163 (4), 723-728, 2003 | 446 | 2003 |
Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons A Falk, P Koch, J Kesavan, Y Takashima, J Ladewig, M Alexander, ... PloS one 7 (1), e29597, 2012 | 336 | 2012 |
Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation C Dahlqvist, A Blokzijl, G Chapman, A Falk, K Dannaeus, CF Ibâñez, ... Oxford University Press for The Company of Biologists Limited 130 (24), 6089 …, 2003 | 306 | 2003 |
Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture Y Sun, S Pollard, L Conti, M Toselli, G Biella, G Parkin, L Willatt, A Falk, ... Molecular and Cellular Neuroscience 38 (2), 245-258, 2008 | 295 | 2008 |
Treatment of a mouse model of spinal cord injury by transplantation of human induced pluripotent stem cell-derived long-term self-renewing neuroepithelial-like stem cells Y Fujimoto, M Abematsu, A Falk, K Tsujimura, T Sanosaka, B Juliandi, ... Stem cells 30 (6), 1163-1173, 2012 | 276 | 2012 |
A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons D Zhang, M Pekkanen-Mattila, M Shahsavani, A Falk, AI Teixeira, ... Biomaterials 35 (5), 1420-1428, 2014 | 199 | 2014 |
CD133 (Prominin) negative human neural stem cells are clonogenic and tripotent Y Sun, W Kong, A Falk, J Hu, L Zhou, S Pollard, A Smith PloS one 4 (5), e5498, 2009 | 170 | 2009 |
Gene delivery to adult neural stem cells A Falk, N Holmström, M Carlén, R Cassidy, C Lundberg, J Frisén Experimental cell research 279 (1), 34-39, 2002 | 114 | 2002 |
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates J Rostami, T Mothes, M Kolahdouzan, O Eriksson, M Moslem, J Bergström, ... Journal of neuroinflammation 18 (1), 124, 2021 | 110 | 2021 |
Human iPS-derived astroglia from a stable neural precursor state show improved functionality compared with conventional astrocytic models A Lundin, L Delsing, M Clausen, P Ricchiuto, J Sanchez, A Sabirsh, ... Stem cell reports 10 (3), 1030-1045, 2018 | 108 | 2018 |
Amphiregulin is a mitogen for adult neural stem cells A Falk, J Frisén Journal of neuroscience research 69 (6), 757-762, 2002 | 108 | 2002 |
Barrier properties and transcriptome expression in human iPSC-derived models of the blood–brain barrier L Delsing, P Dönnes, J Sánchez, M Clausen, D Voulgaris, A Falk, ... Stem cells 36 (12), 1816-1827, 2018 | 104 | 2018 |
Modeling psychiatric disorders: from genomic findings to cellular phenotypes A Falk, VM Heine, AJ Harwood, PF Sullivan, M Peitz, O Brüstle, S Shen, ... Molecular psychiatry 21 (9), 1167-1179, 2016 | 103 | 2016 |
TRIM28 controls a gene regulatory network based on endogenous retroviruses in human neural progenitor cells PL Brattås, ME Jönsson, L Fasching, JN Wahlestedt, M Shahsavani, ... Cell reports 18 (1), 1-11, 2017 | 100 | 2017 |
Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells R Falk, A Falk, MR Dyson, AN Melidoni, K Parthiban, JL Young, W Roake, ... Methods 58 (1), 69-78, 2012 | 95 | 2012 |
Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency J Tailor, R Kittappa, K Leto, M Gates, M Borel, O Paulsen, S Spitzer, ... Journal of Neuroscience 33 (30), 12407-12422, 2013 | 94 | 2013 |
A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease JC Villaescusa, B Li, EM Toledo, PIA Rivetti di Val Cervo, S Yang, ... The EMBO journal 35 (18), 1963-1978, 2016 | 93 | 2016 |
The roots of autism and ADHD twin study in Sweden (RATSS) S Bölte, C Willfors, S Berggren, J Norberg, L Poltrago, K Mevel, C Coco, ... Twin Research and Human Genetics 17 (3), 164-176, 2014 | 81 | 2014 |
Models of the blood-brain barrier using iPSC-derived cells L Delsing, A Herland, A Falk, R Hicks, J Synnergren, H Zetterberg Molecular and Cellular Neuroscience 107, 103533, 2020 | 56 | 2020 |
p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids A Marin Navarro, RJ Pronk, AT van der Geest, G Oliynyk, A Nordgren, ... Cell death & disease 11 (1), 52, 2020 | 54 | 2020 |