| Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency K Cong, M Peng, AN Kousholt, WTC Lee, S Lee, S Nayak, J Krais, ... Molecular cell 81 (15), 3128-3144. e7, 2021 | 227 | 2021 |
| Easy quantification of template-directed CRISPR/Cas9 editing EK Brinkman, AN Kousholt, T Harmsen, C Leemans, T Chen, J Jonkers, ... Nucleic acids research 46 (10), e58-e58, 2018 | 192 | 2018 |
| SET8 is degraded via PCNA-coupled CRL4 (CDT2) ubiquitylation in S phase and after UV irradiation S Jørgensen, M Eskildsen, K Fugger, L Hansen, MS Yoo Larsen, ... Journal of Cell Biology 192 (1), 43-54, 2011 | 127 | 2011 |
| FBH1 catalyzes regression of stalled replication forks K Fugger, M Mistrik, KJ Neelsen, Q Yao, R Zellweger, AN Kousholt, ... Cell reports 10 (10), 1749-1757, 2015 | 114 | 2015 |
| FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress K Fugger, W Kit Chu, P Haahr, A Nedergaard Kousholt, H Beck, MJ Payne, ... Nature communications 4 (1), 1423, 2013 | 93 | 2013 |
| CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation AN Kousholt, K Fugger, S Hoffmann, BD Larsen, T Menzel, AA Sartori, ... Journal of Cell Biology 197 (7), 869-876, 2012 | 92 | 2012 |
| A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance T Menzel, V Nähse‐Kumpf, AN Kousholt, DK Klein, C Lund‐Andersen, ... EMBO reports 12 (7), 705-712, 2011 | 90 | 2011 |
| Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control DK Klein, S Hoffmann, JK Ahlskog, K O’Hanlon, M Quaas, BD Larsen, ... Nature communications 6 (1), 5800, 2015 | 69 | 2015 |
| Pathways for genome integrity in G2 phase of the cell cycle AN Kousholt, T Menzel, CS Sørensen Biomolecules 2 (4), 579-607, 2012 | 54 | 2012 |
| Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation AN Monteiro, P Bouwman, AN Kousholt, DM Eccles, GA Millot, JY Masson, ... Journal of medical genetics 57 (8), 509-518, 2020 | 43 | 2020 |
| Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability R Zarrizi, MR Higgs, K Voßgröne, M Rossing, B Bertelsen, M Bose, ... The Journal of clinical investigation 130 (8), 4069-4080, 2020 | 28 | 2020 |
| miR-19, a component of the oncogenic miR-17∼ 92 cluster, targets the DNA-end resection factor CtIP D Hühn, AN Kousholt, CS Sørensen, AA Sartori Oncogene 34 (30), 3977-3984, 2015 | 28 | 2015 |
| PARPi synthetic lethality derives from replication-associated single-stranded DNA gaps K Cong, AN Kousholt, M Peng, NJ Panzarino, WTC Lee, S Nayak, J Krais, ... BioRxiv, 781989, 2019 | 23 | 2019 |
| Syljuå sen, RG, Trelle, MB, Jensen, ON, Helin, K., and Sørensen, CS (2011). SET8 is degraded via PCNA-coupled CRL4 (CDT2) ubiquitylation in S phase and after UV irradiation S Jørgensen, M Eskildsen, K Fugger, L Hansen, MS Larsen, AN Kousholt J. Cell Biol 192, 43-54, 0 | 6 | |
| Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens Y Zhao, D Tabet, DR Contreras, L Lao, AN Kousholt, J Weile, H Melo, ... Molecular Cell 83 (15), 2792-2809. e9, 2023 | 5 | 2023 |
| Article FBH1 Catalyzes Regression of Stalled Replication Forks K Fugger, M Mistrik, ID Hickson, CS Sørensen, K Fugger, M Mistrik, ... CellReports 10 (10), 1749-1757, 2015 | 3 | 2015 |
| H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours D Dibitetto, M Liptay, F Vivalda, H Dogan, E Gogola, ... Nature communications 15 (1), 4430, 2024 | | 2024 |
| Genome-scale mapping of DNA damage suppressors identifies GNB1L as essential for ATM and ATR biogenesis Y Zhao, D Tabet, DR Contreras, AN Kousholt, J Weile, H Melo, L Hoeg, ... bioRxiv, 2022.09. 23.508845, 2022 | | 2022 |
| PO-205 Functional characterisation of BRIP1/FANCJ in tumour suppression and therapy response AN Kousholt, P Bouwman, J Jonkers ESMO Open 3, A307, 2018 | | 2018 |
| Correction: Kousholt, A.N. et al. Pathways for Genome Integrity in G2 Phase of the Cell Cycle. Biomolecules 2012, 2, 579-607 AN Kousholt, T Menzel, CS Sørensen Biomolecules 3 (1), 72-74, 2013 | | 2013 |
