Recently reported biological activities of pyrazole compounds JV Faria, PF Vegi, AGC Miguita, MS Dos Santos, N Boechat, ... Bioorganic & medicinal chemistry 25 (21), 5891-5903, 2017 | 380 | 2017 |
Novel 1,2,3-Triazole Derivatives for Use against Mycobacterium tuberculosis H37Rv (ATCC 27294) Strain N Boechat, VF Ferreira, SB Ferreira, MLG Ferreira, FC da Silva, ... Journal of medicinal chemistry 54 (17), 5988-5999, 2011 | 309 | 2011 |
Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1, 2, 3-triazole derivatives MS Costa, N Boechat, EA Rangel, FC Da Silva, AMT De Souza, ... Bioorganic & medicinal chemistry 14 (24), 8644-8653, 2006 | 251 | 2006 |
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication CQ Sacramento, GR de Melo, CS de Freitas, N Rocha, LVB Hoelz, ... Scientific reports 7 (1), 40920, 2017 | 237 | 2017 |
Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs M de Lourdes G. Ferreira, LCS Pinheiro, OA Santos-Filho, MDS Peçanha, ... Medicinal Chemistry Research 23, 1501-1511, 2014 | 134 | 2014 |
Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents SB Ferreira, MS Costa, N Boechat, RJS Bezerra, MS Genestra, ... European Journal of Medicinal Chemistry 42 (11-12), 1388-1395, 2007 | 110 | 2007 |
Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate F de Pilla Varotti, ACC Botelho, AA Andrade, RC de Paula, ... Antimicrobial Agents and Chemotherapy 52 (11), 3868-3874, 2008 | 105 | 2008 |
Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo CS de Freitas, LM Higa, CQ Sacramento, AC Ferreira, PA Reis, ... PLoS neglected tropical diseases 13 (1), e0007072, 2019 | 104 | 2019 |
Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication AC Ferreira, PA Reis, CS de Freitas, CQ Sacramento, L Villas Bôas Hoelz, ... Antimicrobial agents and chemotherapy 63 (2), 10.1128/aac. 01389-18, 2019 | 89 | 2019 |
Current antimalarial therapies and advances in the development of semi-synthetic artemisinin derivatives L Pinheiro, LM Feitosa, FF SILVEIRA, N Boechat Anais da Academia Brasileira de Ciências 90, 1251-1271, 2018 | 84 | 2018 |
New Compounds Hybrids 1H‐1,2,3‐Triazole‐Quinoline Against Plasmodium falciparum N Boechat, MLG Ferreira, LCS Pinheiro, AML Jesus, MMM Leite, ... Chemical Biology & Drug Design 84 (3), 325-332, 2014 | 82 | 2014 |
Novel 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole derivatives: a patent review (2008 – 2011) VF Ferreira, DR da Rocha, FC da Silva, PG Ferreira, NA Boechat, ... Expert Opinion on Therapeutic Patents 23 (3), 319-331, 2013 | 73 | 2013 |
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19 CQ Sacramento, N Fintelman-Rodrigues, JR Temerozo, APD Da Silva, ... Journal of Antimicrobial Chemotherapy 76 (7), 1874-1885, 2021 | 70 | 2021 |
Evaluation of 7-arylaminopyrazolo [1, 5-a] pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors LFSP Azeredo, JP Coutinho, VAP Jabor, PR Feliciano, MC Nonato, ... European Journal of Medicinal Chemistry 126, 72-83, 2017 | 70 | 2017 |
New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodiumfalciparum Agents N Boechat, LCS Pinheiro, TS Silva, ACC Aguiar, AS Carvalho, MM Bastos, ... Molecules 17 (7), 8285-8302, 2012 | 70 | 2012 |
A synthesis of 3-fluoroindoles and 3, 3-difluoroindolines by reduction of 3, 3-difluoro-2-oxindoles using a borane tetrahydrofuran complex JC Torres, SJ Garden, AC Pinto, FSQ da Silva, N Boechat Tetrahedron 55 (7), 1881-1892, 1999 | 68 | 1999 |
Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes N Boechat, LCS Pinheiro, OA Santos-Filho, IC Silva Molecules 16 (9), 8083-8097, 2011 | 67 | 2011 |
The development of novel compounds against malaria: quinolines, triazolpyridines, pyrazolopyridines and pyrazolopyrimidines L CS Pinheiro, L M. Feitosa, M O. Gandi, F F. Silveira, N Boechat Molecules 24 (22), 4095, 2019 | 62 | 2019 |
Efavirenz a nonnucleoside reverse transcriptase inhibitor of first-generation: Approaches based on its medicinal chemistry MM Bastos, CCP Costa, TC Bezerra, FC da Silva, N Boechat European journal of medicinal chemistry 108, 455-465, 2016 | 58 | 2016 |
A simple reduction of methyl aromatic esters to alcohols using sodium borohydride–methanol system N Boechat, JCS da Costa, J de Souza Mendonça, PSM de Oliveira, ... Tetrahedron letters 45 (31), 6021-6022, 2004 | 56 | 2004 |