Cell fate decision mediated by p53 pulses XP Zhang, F Liu, Z Cheng, W Wang Proceedings of the National Academy of Sciences 106 (30), 12245-12250, 2009 | 293 | 2009 |
N6-methyladenine DNA modification in glioblastoma Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ... Cell 175 (5), 1228-1243. e20, 2018 | 279 | 2018 |
Single-cell chromatin accessibility identifies pancreatic islet cell type–and state-specific regulatory programs of diabetes risk J Chiou, C Zeng, Z Cheng, JY Han, M Schlichting, M Miller, R Mendez, ... Nature genetics 53 (4), 455-466, 2021 | 156 | 2021 |
High-content quantification of single-cell immune dynamics M Junkin, AJ Kaestli, Z Cheng, C Jordi, C Albayrak, A Hoffmann, S Tay Cell reports 15 (2), 411-422, 2016 | 141 | 2016 |
Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation Z Cheng, B Taylor, DR Ourthiague, A Hoffmann Science signaling 8 (385), ra69-ra69, 2015 | 139 | 2015 |
Network dynamics determine the autocrine and paracrine signaling functions of TNF AB Caldwell, Z Cheng, JD Vargas, HA Birnbaum, A Hoffmann Genes & development 28 (19), 2120-2133, 2014 | 113 | 2014 |
Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation Y Zhou, IN Bastian, MD Long, M Dow, W Li, T Liu, RK Ngu, L Antonucci, ... Proceedings of the National Academy of Sciences 118 (8), e2025840118, 2021 | 77 | 2021 |
Gene regulatory strategies that decode the duration of NFκB dynamics contribute to LPS-versus TNF-specific gene expression S Sen, Z Cheng, KM Sheu, YH Chen, A Hoffmann Cell systems 10 (2), 169-182. e5, 2020 | 64 | 2020 |
Dissecting the regulatory strategies of NF-κB RelA target genes in the inflammatory response reveals differential transactivation logics KA Ngo, K Kishimoto, J Davis-Turak, A Pimplaskar, Z Cheng, R Spreafico, ... Cell reports 30 (8), 2758-2775. e6, 2020 | 61 | 2020 |
Linking fast and slow positive feedback loops creates an optimal bistable switch in cell signaling XP Zhang, Z Cheng, F Liu, W Wang Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 76 (3 …, 2007 | 56 | 2007 |
Robustness analysis of cellular memory in an autoactivating positive feedback system Z Cheng, F Liu, XP Zhang, W Wang FEBS letters 582 (27), 3776-3782, 2008 | 47 | 2008 |
Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism EM Padhi, TJ Hayeck, Z Cheng, S Chatterjee, BJ Mannion, ... Human genomics 15, 1-15, 2021 | 24 | 2021 |
Reversible phosphorylation subserves robust circadian rhythms by creating a switch in inactivating the positive element Z Cheng, F Liu, XP Zhang, W Wang Biophysical journal 97 (11), 2867-2875, 2009 | 13 | 2009 |
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer CE Antal, TG Oh, S Aigner, EC Luo, BA Yee, T Campos, H Tiriac, ... Nature communications 14 (1), 5195, 2023 | 11 | 2023 |
IκBα nuclear export enables 4-1BB–induced cRel activation and IL-2 production to promote CD8 T cell immunity DN Lisiero, Z Cheng, MM Tejera, BT Neldner, JW Warrick, ... The Journal of Immunology 205 (6), 1540-1553, 2020 | 10 | 2020 |
Rapid changes in chromatin structure during dedifferentiation of primary hepatocytes in vitro M Seirup, S Sengupta, S Swanson, BE McIntosh, M Collins, LF Chu, ... Genomics 114 (3), 110330, 2022 | 9 | 2022 |
Kinetics of mRNA nuclear export regulate innate immune response gene expression D Lefaudeux, S Sen, K Jiang, A Hoffmann Nature communications 13 (1), 7197, 2022 | 7 | 2022 |
A stochastic spatio-temporal (SST) model to study cell-to-cell variability in HIV-1 infection Z Cheng, A Hoffmann Journal of Theoretical Biology 395, 87-96, 2016 | 7 | 2016 |
Single cell chromatin accessibility reveals pancreatic islet cell type-and state-specific regulatory programs of diabetes risk. bioRxiv, 693671 J Chiou, C Zeng, Z Cheng, JY Han, M Schlichting, S Huang, J Wang, ... | 6 | 2019 |
Modeling the crosstalk between the circadian clock and ROS in Neurospora crassa Y Xia, Z Cheng, S Wang, D Guan, F Liu Journal of Theoretical Biology 458, 125-132, 2018 | 6 | 2018 |