| In vitro-engineered non-antibody protein therapeutics R Simeon, Z Chen Protein Cell 9 (1), 3-14, 2018 | 209 | 2018 |
| A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle K Chockalingam, RL Simeon, CM Rice, Z Chen Proceedings of the National Academy of Sciences 107 (8), 3764-3769, 2010 | 92 | 2010 |
| Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes AM Chamoun-Emanuelli, EI Pecheur, RL Simeon, D Huang, PS Cremer, ... Antimicrobial agents and chemotherapy 57 (6), 2571-2581, 2013 | 63 | 2013 |
| PD 404,182 is a virocidal small molecule that disrupts hepatitis C virus and human immunodeficiency virus AM Chamoun, K Chockalingam, M Bobardt, R Simeon, J Chang, P Gallay, ... Antimicrobial agents and chemotherapy 56 (2), 672-681, 2012 | 46 | 2012 |
| Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B R Simeon, M Jiang, AM Chamoun-Emanuelli, H Yu, Y Zhang, R Meng, ... PLoS biology 17 (6), e3000311, 2019 | 33 | 2019 |
| Designed Ankyrin Repeat Protein (DARPin) Neutralizers of TcdB from Clostridium difficile Ribotype 027 Z Peng, R Simeon, SB Mitchell, J Zhang, H Feng, Z Chen mSphere 4 (5), e00596-19, 2019 | 20 | 2019 |
| A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins V Chonira, YD Kwon, J Gorman, JB Case, Z Ku, R Simeon, RG Casner, ... Nature Chemical Biology, 1-8, 2022 | 16 | 2022 |
| Structural dynamics of receptor recognition and pH-induced dissociation of full-length Clostridioides difficile Toxin B M Jiang, J Shin, R Simeon, JY Chang, R Meng, Y Wang, O Shinde, P Li, ... PLoS Biology 20 (3), e3001589, 2022 | 15 | 2022 |
| Discovery and characterization of a new cell-penetrating protein RL Simeon, AM Chamoun, T McMillin, Z Chen ACS chemical biology 8 (12), 2678-2687, 2013 | 14 | 2013 |
| Creation and characterization of a cell-death reporter cell line for hepatitis C virus infection Z Chen, RL Simeon, K Chockalingam, CM Rice Antiviral research 86 (2), 220-223, 2010 | 10 | 2010 |
| Protease-stable DARPins as promising oral therapeutics RA Simeon, Y Zeng, V Chonira, AM Aguirre, M Lasagna, M Baloh, ... Protein Engineering, Design and Selection 34, 2021 | 4 | 2021 |
| A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits Y Zeng, M Jiang, S Robinson, Z Peng, V Chonira, R Simeon, S Tzipori, ... Bioengineering 9 (10), 511, 2022 | 2 | 2022 |
| A Screen for Genetic Suppressor Elements of Hepatitis C Virus Identifies a Supercharged Protein Inhibitor of Viral Replication RL Simeon, Z Chen PloS one 8 (12), e84022, 2013 | 2 | 2013 |
| De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions P Heinzelman, A Low, R Simeon, GA Wright, Z Chen Journal of biological engineering 13 (1), 76, 2019 | 1 | 2019 |
| Protein inhibitors of clostridium difficile toxin b Z Chen, R Simeon, AM Chamoun-Emanuelli, P Zeyu, H Feng, H Yu, ... US Patent App. 17/609,818, 2022 | | 2022 |
| Virucidal small molecule and uses thereof Z Chen, K Chockalingam, AM Chamoun-Emanuelli, R Simeon, M Bobardt, ... US Patent App. 14/023,437, 2014 | | 2014 |
| Virucidal small molecule and uses thereof Z Chen, K Chockalingam, AM Chamoun-Emanuelli, R Simeon, M Bobardt, ... US Patent App. 14/023,434, 2014 | | 2014 |
| Selecting a path against Hepatitis C Virus RL Simeon | | 2013 |
| PD 404,182 as an HIV microbicide candidate AM Chamoun-Emanuelli, K Chockalingam, M Bobardt, R Simeon, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
| B1 mediated protein transfection RL Simeon, AM Chamoun, TC McMillan, Z Chen ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
