Leukemic stem cells evade chemotherapy by metabolic adaptation to an adipose tissue niche H Ye, B Adane, N Khan, T Sullivan, M Minhajuddin, M Gasparetto, ... Cell stem cell 19 (1), 23-37, 2016 | 515 | 2016 |
Inhibition of amino acid metabolism selectively targets human leukemia stem cells CL Jones, BM Stevens, A D'Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ... Cancer cell 34 (5), 724-740. e4, 2018 | 503 | 2018 |
Monocytic subclones confer resistance to venetoclax-based therapy in patients with acute myeloid leukemia S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ... Cancer discovery 10 (4), 536-551, 2020 | 390 | 2020 |
Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells BM Stevens, CL Jones, DA Pollyea, R Culp-Hill, A D’Alessandro, ... Nature cancer 1 (12), 1176-1187, 2020 | 230 | 2020 |
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ... Journal of Biological Chemistry 288 (47), 33542-33558, 2013 | 230 | 2013 |
Nicotinamide metabolism mediates resistance to venetoclax in relapsed acute myeloid leukemia stem cells CL Jones, BM Stevens, DA Pollyea, R Culp-Hill, JA Reisz, T Nemkov, ... Cell stem cell 27 (5), 748-764. e4, 2020 | 189 | 2020 |
Subversion of systemic glucose metabolism as a mechanism to support the growth of leukemia cells H Ye, B Adane, N Khan, E Alexeev, N Nusbacher, M Minhajuddin, ... Cancer cell 34 (4), 659-673. e6, 2018 | 120 | 2018 |
The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation ML Amaya, A Inguva, S Pei, C Jones, A Krug, H Ye, M Minhajuddin, ... Blood, The Journal of the American Society of Hematology 139 (4), 584-596, 2022 | 85 | 2022 |
The hematopoietic oxidase NOX2 regulates self-renewal of leukemic stem cells B Adane, H Ye, N Khan, S Pei, M Minhajuddin, BM Stevens, CL Jones, ... Cell reports 27 (1), 238-254. e6, 2019 | 75 | 2019 |
Repressing malic enzyme 1 redirects glucose metabolism, unbalances the redox state, and attenuates migratory and invasive abilities in nasopharyngeal carcinoma cell lines FJ Zheng, HB Ye, MS Wu, YF Lian, CN Qian, YX Zeng Chinese journal of cancer 31 (11), 519, 2012 | 60 | 2012 |
Inhibition of amino acid metabolism selectively targets human leukemia stem cells CL Jones, BM Stevens, A D’Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ... Cancer Cell 35 (2), 333-335, 2019 | 57 | 2019 |
The hepatic microenvironment uniquely protects leukemia cells through induction of growth and survival pathways mediated by LIPG H Ye, M Minhajuddin, A Krug, S Pei, CH Chou, R Culp-Hill, J Ponder, ... Cancer discovery 11 (2), 500-519, 2021 | 21 | 2021 |
Adipose tissue functions as a reservoir for leukemia stem cells and confers chemo-resistance H Ye, B Adane, N Khan, JM Ashton, M Balys, BM Stevens, M Minhajuddin, ... Blood 126 (23), 845, 2015 | 3 | 2015 |
Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia M Minhajuddin, A Winters, H Ye, S Pei, B Stevens, A Gillen, K Engel, ... Haematologica, 2020 | 2 | 2020 |
Developmental plasticity of acute myeloid leukemia mediates resistance to venetoclax-based therapy S Pei, DA Pollyea, A Gustafson, M Minhajuddin, BM Stevens, H Ye, ... Blood 134, 185, 2019 | 2 | 2019 |
Lysosomal Acid Lipase a (LIPA) Modulates Leukemia Stem Cell (LSC) Response to Venetoclax/TKI Combination Therapy in Blast Phase Chronic Myeloid Leukemia M Minhajuddin, H Ye, AC Winters, S Pei, N Khan, BM Stevens, B Adane, ... Blood 138, 630, 2021 | 1 | 2021 |
Cysteine and Cystine Depletion Targets Leukemia Stem Cells CL Jones, BM Stevens, A D'Alessandro, R Culp-Hill, J Reisz, H Ye, ... Blood 132, 431, 2018 | | 2018 |
Adipose Tissue-Derived IGFBP1 Facilitates Progression of Leukemia H Ye, N Khan, M Minhajuddin, B Adane, CT Jordan Blood 128 (22), 3058, 2016 | | 2016 |
The Role of NADPH Oxidase 2 in Normal and Malignant Hematopoiesis B Adane, H Ye, S Pei, N Khan, M Minhajuddin, BM Stevens, ... Blood 128 (22), 1079, 2016 | | 2016 |
Leukemia Cells Resident in Adipose Tissue Display a Pro-Inflammatory Phenotype and Induce Lipolysis and Atrophy of Adipose Tissue H Ye, N Khan, M Balys, JM Ashton, B Adane, CT Jordan Blood 126 (23), 2765, 2015 | | 2015 |