| Genome editing with mRNA encoding ZFN, TALEN, and Cas9 HX Zhang, Y Zhang, H Yin Molecular Therapy 27 (4), 735-746, 2019 | 233 | 2019 |
| Lens regeneration using endogenous stem cells with gain of visual function H Lin, H Ouyang, J Zhu, S Huang, Z Liu, S Chen, G Cao, G Li, RAJ Signer, ... Nature 531 (7594), 323-328, 2016 | 219 | 2016 |
| Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size JF Chen, Y Zhang, J Wilde, KC Hansen, F Lai, L Niswander Nature communications 5 (1), 3885, 2014 | 171 | 2014 |
| Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a S Lu, X Tong, Y Han, K Zhang, Y Zhang, Q Chen, J Duan, X Lei, M Huang, ... Nature biomedical engineering 6 (3), 286-297, 2022 | 140 | 2022 |
| Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival A Marean, A Graf, Y Zhang, L Niswander Human molecular genetics 20 (18), 3678-3683, 2011 | 98 | 2011 |
| Efficient targeted insertion of large DNA fragments without DNA donors J Wang, Z He, G Wang, R Zhang, J Duan, P Gao, X Lei, H Qiu, C Zhang, ... Nature methods 19 (3), 331-340, 2022 | 95 | 2022 |
| Rapid detection of African swine fever virus using Cas12a-based portable paper diagnostics S Lu, F Li, Q Chen, J Wu, J Duan, X Lei, Y Zhang, D Zhao, Z Bu, H Yin Cell discovery 6 (1), 18, 2020 | 83 | 2020 |
| Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity Y Zhang, TH Kim, L Niswander Genes & development 26 (1), 69-81, 2012 | 76 | 2012 |
| Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations L Wang, W Xue, H Zhang, R Gao, H Qiu, J Wei, L Zhou, YN Lei, X Wu, X Li, ... Nature Cell Biology 23 (5), 552-563, 2021 | 70 | 2021 |
| Recent advances in chemical modifications of guide RNA, mRNA and donor template for CRISPR-mediated genome editing Q Chen, Y Zhang, H Yin Advanced Drug Delivery Reviews 168, 246-258, 2021 | 57 | 2021 |
| Purification and cloning of a novel serine protease from the nematode-trapping fungus Dactylellina varietas and its potential roles in infection against nematodes J Yang, L Liang, Y Zhang, J Li, L Zhang, F Ye, Z Gan, KQ Zhang Applied microbiology and biotechnology 75, 557-565, 2007 | 53 | 2007 |
| Crim1 regulates integrin signaling in murine lens development Y Zhang, J Fan, JWK Ho, T Hu, SC Kneeland, X Fan, Q Xi, MA Sellarole, ... Development 143 (2), 356-366, 2016 | 34 | 2016 |
| DNA topology regulates PAM-Cas9 interaction and DNA unwinding to enable near-PAMless cleavage by thermophilic Cas9 YJ Shi, M Duan, JM Ding, FQ Wang, LL Bi, CX Zhang, YZ Zhang, JY Duan, ... Molecular Cell 82 (21), 4160-4175. e6, 2022 | 18 | 2022 |
| Current advances of CRISPR-Cas technology in cell therapy HY Qiu, RJ Ji, Y Zhang Cell Insight 1 (6), 100067, 2022 | 16 | 2022 |
| Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS–STING pathway J An, CP Zhang, HY Qiu, HX Zhang, QB Chen, YM Zhang, XL Lei, ... Nature Biomedical Engineering 8 (2), 149-164, 2024 | 13 | 2024 |
| Phactr4: a new integrin modulator required for directional migration of enteric neural crest cells Y Zhang, L Niswander Cell adhesion & migration 6 (5), 419-423, 2012 | 13 | 2012 |
| Zic2 is required for enteric nervous system development and neurite outgrowth: a mouse model of enteric hyperplasia and dysplasia Y Zhang, L Niswander Neurogastroenterology & Motility 25 (6), 538-541, 2013 | 11 | 2013 |
| Cas12a-based one-pot SNP detection with high accuracy HX Zhang, C Zhang, S Lu, X Tong, K Zhang, H Yin, Y Zhang Cell insight 2 (2), 100080, 2023 | 8 | 2023 |
| Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs W Han, HY Qiu, S Sun, ZC Fu, GQ Wang, X Qian, L Wang, X Zhai, J Wei, ... Cell Stem Cell 30 (12), 1624-1639. e8, 2023 | 7 | 2023 |
| Corrigendum: Lens regeneration using endogenous stem cells with gain of visual function H Lin, H Ouyang, J Zhu, S Huang, Z Liu, S Chen, G Cao, G Li, RAJ Signer, ... Nature 541 (7638), 558-558, 2017 | 7 | 2017 |
