Type I interferon receptor signaling of neurons and astrocytes regulates microglia activation during viral encephalitis C Chhatbar, CN Detje, E Grabski, K Borst, J Spanier, L Ghita, DA Elliott, ... Cell reports 25 (1), 118-129. e4, 2018 | 93 | 2018 |
Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage I Waltl, C Käufer, I Gerhauser, C Chhatbar, L Ghita, U Kalinke, W Löscher Brain, behavior, and immunity 74, 186-204, 2018 | 81 | 2018 |
Macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis I Waltl, C Käufer, S Bröer, C Chhatbar, L Ghita, I Gerhauser, M Anjum, ... Neurobiology of disease 110, 192-205, 2018 | 56 | 2018 |
Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures C Käufer, C Chhatbar, S Bröer, I Waltl, L Ghita, I Gerhauser, U Kalinke, ... Proceedings of the National Academy of Sciences 115 (38), E8929-E8938, 2018 | 54 | 2018 |
Type I interferon receptor signaling delays Kupffer cell replenishment during acute fulminant viral hepatitis K Borst, T Frenz, J Spanier, PK Tegtmeyer, C Chhatbar, J Skerra, L Ghita, ... Journal of hepatology 68 (4), 682-690, 2018 | 54 | 2018 |
STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus PK Tegtmeyer, J Spanier, K Borst, J Becker, A Riedl, C Hirche, L Ghita, ... Nature communications 10 (1), 2830, 2019 | 41 | 2019 |
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies M Karim, S Saul, L Ghita, MK Sahoo, C Ye, N Bhalla, CW Lo, J Jin, ... Antiviral Research 204, 105367, 2022 | 19 | 2022 |
MyD88 signaling by neurons induces chemokines that recruit protective leukocytes to the virus-infected CNS L Ghita, J Spanier, C Chhatbar, F Mulenge, A Pavlou, PK Larsen, I Waltl, ... Science immunology 6 (60), eabc9165, 2021 | 14 | 2021 |
Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen. S Saul, M Karim, PT Huang, L Ghita, W Chiu, S Kumar, N Bhalla, ... Biorxiv: the Preprint Server for Biology, 2021 | 14 | 2021 |
Toll-like receptors in viral encephalitis OL Gern, F Mulenge, A Pavlou, L Ghita, I Steffen, M Stangel, U Kalinke Viruses 13 (10), 2065, 2021 | 13 | 2021 |
Type I interferon receptor signaling of neurons and astrocytes regulates microglia activation during viral encephalitis. Cell Rep 25: 118–129. e114 C Chhatbar, CN Detje, E Grabski, K Borst, J Spanier, L Ghita, DA Elliott, ... | 10 | 2018 |
Sequential MAVS and MyD88/TRIF signaling triggers anti‐viral responses of tick‐borne encephalitis virus‐infected murine astrocytes L Ghita, V Breitkopf, F Mulenge, A Pavlou, OL Gern, V Durán, CK Prajeeth, ... Journal of neuroscience research 99 (10), 2478-2492, 2021 | 9 | 2021 |
Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach L Ghita, Z Yao, Y Xie, V Duran, HB Cagirici, J Samir, I Osman, ... Nature immunology 24 (12), 2150-2163, 2023 | 5 | 2023 |
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects S Saul, M Karim, L Ghita, PT Huang, W Chiu, V Durán, CW Lo, S Kumar, ... The Journal of Clinical Investigation 133 (19), 2023 | 5 | 2023 |
Global and cell type-specific immunological hallmarks of severe dengue progression L Ghita, Z Yao, Y Xie, V Duran, HB Cagirici, J Samir, I Osman, ... Biorxiv, 2022.12. 11.519930, 2022 | 1 | 2022 |
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy M Karim, S Saul, L Ghita, MK Sahoo, C Ye, N Bhalla, J Jin, JG Park, ... bioRxiv, 2022.03. 18.484178, 2022 | 1 | 2022 |
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2 M Karim, M Mishra, CW Lo, S Saul, HB Cagirici, A Agrawal, L Ghita, ... bioRxiv, 2024 | | 2024 |
MAVS signaling in microglia transcriptionally defines the functionality of CNS infiltrating CD8+ T cells during viral encephalitis A Pavlou, L Ghita, F Mulenge, I Waltl, O Gern, P Larsen, B Costa, V Duran, ... European journal of immunology 52 (Suppl. 1), 260, 2022 | | 2022 |
MAVS is required to mount IFN-β-and cytokine responses in VSV infected microglia O Gern, A Pavlou, F Mulenge, L Ghita, V Durán, B Costa, A Aringo, ... 14th Graduate School Days: 19/20 November 2021: University of Veterinary …, 2021 | | 2021 |
Towards novel treatment strategies against viral encephalitis: dissecting sensing mechanisms of RNA viruses by resident cells of the central nervous system O Gern, L Ghita, A Pavlou, F Mulenge, V Breitkopf, I Steffen, M Stangel, ... 13th Graduate School Days: 20/21 November 2020/Stiftung Tierärztliche …, 2020 | | 2020 |