A Crispr-Cas9 system designed to introduce point mutations into the human ACE2 gene to weaken the interaction of the ACE2 receptor with the SARS-CoV-2 S protein P Tanaka, J Santos, E Oliveira, N Miglioli, A Assis, ... Preprints, 2020 | 15 | 2020 |
The thymus as a mirror of the body’s gene expression GA Passos, AB Genari, AF Assis, AC Monteleone-Cassiano, EA Donadi, ... Thymus transcriptome and cell biology, 215-234, 2019 | 9 | 2019 |
The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids AC Monteleone-Cassiano, JA Dernowsek, RS Mascarenhas, AF Assis, ... BMC Molecular and Cell Biology 23 (1), 15, 2022 | 2 | 2022 |
A mimetic peptide of ACE2 protects against SARS-CoV-2 infection and decreases pulmonary inflammation related to COVID-19 EH Oliveira, AC Monteleone-Cassiano, L Tavares, JC Santos, TM Lima, ... Antiviral Research 229, 105968, 2024 | 1 | 2024 |
The ribonucleoprotein-mediated CRISPR–Cas9 system induces recurrent Aire gene mutations in contrast to the nickase expression vector in murine in vitro or in vivo models PP Tanaka, CJ Monteiro, MJ Duarte, ED Oliveira, ... bioRxiv, 2023.10. 13.562266, 2023 | 1 | 2023 |
Mutação no gene Aire induzida pelo sistema CRISPR-Cas9 em modelo murino in vitro (células epiteliais medulares tímicas): impacto na adesão intercelular e na apresentação de … ACM Cassiano Universidade de São Paulo, 2024 | | 2024 |
Aire gene influences mTEC-mTEC cell aggregation on a three-dimensional spheroid formation model system ACM Cassiano, DL Pitol, JA Dernowsek, MCV Machado, ... Resumos, 2019 | | 2019 |
Effect of aire gene on the chemotactic properties of medullary thymic epithelial cells on thymocytes MCV Machado, MJ Duarte, PP Tanaka, ACM Cassiano, ... Resumos, 2019 | | 2019 |