Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression ASE Cuomo, DD Seaton, DJ McCarthy, I Martinez, MJ Bonder, ... Nature communications 11 (1), 810, 2020 | 241 | 2020 |
Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation J Jerber, DD Seaton, ASE Cuomo, N Kumasaka, J Haldane, J Steer, ... Nature genetics 53 (3), 304-312, 2021 | 174 | 2021 |
Photoreceptor effects on plant biomass, resource allocation, and metabolic state D Yang, DD Seaton, J Krahmer, KJ Halliday Proceedings of the National Academy of Sciences 113 (27), 7667-7672, 2016 | 131 | 2016 |
Linked circadian outputs control elongation growth and flowering in response to photoperiod and temperature DD Seaton, RW Smith, YH Song, DR MacGregor, K Stewart, G Steel, ... Molecular systems biology 11 (1), 776, 2015 | 112 | 2015 |
Photoperiodic control of the Arabidopsis proteome reveals a translational coincidence mechanism DD Seaton, A Graf, K Baerenfaller, M Stitt, AJ Millar, W Gruissem Molecular systems biology 14 (3), e7962, 2018 | 72 | 2018 |
Photoperiod‐dependent changes in the phase of core clock transcripts and global transcriptional outputs at dawn and dusk in Arabidopsis A Flis, R Sulpice, DD Seaton, AA Ivakov, M Liput, C Abel, AJ Millar, M Stitt Plant, cell & environment 39 (9), 1955-1981, 2016 | 65 | 2016 |
Population-scale proteome variation in human induced pluripotent stem cells BA Mirauta, DD Seaton, D Bensaddek, A Brenes, MJ Bonder, H Kilpinen, ... Elife 9, e57390, 2020 | 60 | 2020 |
Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics MJ Bonder, C Smail, MJ Gloudemans, L Frésard, D Jakubosky, ... Nature genetics 53 (3), 313-321, 2021 | 51 | 2021 |
Dawn and photoperiod sensing by phytochrome A DD Seaton, G Toledo-Ortiz, A Ganpudi, A Kubota, T Imaizumi, KJ Halliday Proceedings of the National Academy of Sciences 115 (41), 10523-10528, 2018 | 45 | 2018 |
Defining the robust behaviour of the plant clock gene circuit with absolute RNA timeseries and open infrastructure A Flis, AP Fernández, T Zielinski, V Mengin, R Sulpice, K Stratford, ... Open Biology 5 (10), 150042, 2015 | 43 | 2015 |
Mathematical models light up plant signaling YH Chew, RW Smith, HJ Jones, DD Seaton, R Grima, KJ Halliday The Plant Cell 26 (1), 5-20, 2014 | 39 | 2014 |
Regulatory principles and experimental approaches to the circadian control of starch turnover DD Seaton, O Ebenhöh, AJ Millar, A Pokhilko Journal of the Royal Society Interface 11 (91), 20130979, 2014 | 33 | 2014 |
Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome AJ Brenes, H Yoshikawa, D Bensaddek, B Mirauta, D Seaton, ... Cell reports 35 (4), 2021 | 32 | 2021 |
Multi-scale modelling to synergise plant systems biology and crop science YH Chew, DD Seaton, AJ Millar Field Crops Research 202, 77-83, 2017 | 22 | 2017 |
An explanatory model of temperature influence on flowering through whole-plant accumulation of FLOWERING LOCUS T in Arabidopsis thaliana HA Kinmonth-Schultz, MJS MacEwen, DD Seaton, AJ Millar, T Imaizumi, ... in silico Plants 1 (1), diz006, 2019 | 20 | 2019 |
Linking circadian time to growth rate quantitatively via carbon metabolism YH Chew, D Seaton, V Mengin, A Flis, ST Mugford, AM Smith, M Stitt, ... | 16 | 2017 |
The coupling of pathways and processes through shared components DD Seaton, J Krishnan BMC systems biology 5, 1-27, 2011 | 16 | 2011 |
Model-based analysis of cell cycle responses to dynamically changing environments DD Seaton, J Krishnan PLoS computational biology 12 (1), e1004604, 2016 | 15 | 2016 |
Systematic assessment of regulatory effects of human disease variants in pluripotent cells MJ Bonder, C Smail, MJ Gloudemans, L Frésard, D Jakubosky, ... bioRxiv, 784967, 2019 | 14 | 2019 |
Modular systems approach to understanding the interaction of adaptive and monostable and bistable threshold processes D Seaton, J Krishnan IET systems biology 5 (2), 81-94, 2011 | 14 | 2011 |