The human complement factor H: functional roles, genetic variations and disease associations SR de Córdoba, J Esparza-Gordillo, EG de Jorge, M Lopez-Trascasa, ... Molecular immunology 41 (4), 355-367, 2004 | 751 | 2004 |
C3 glomerulopathy: consensus report MC Pickering, VD D'agati, CM Nester, RJ Smith, M Haas, GB Appel, ... Kidney international 84 (6), 1079-1089, 2013 | 702 | 2013 |
Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome EG de Jorge, CL Harris, J Esparza-Gordillo, L Carreras, EA Arranz, ... Proceedings of the National Academy of Sciences 104 (1), 240-245, 2007 | 543 | 2007 |
Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H SR De Córdoba, EG De Jorge Clinical & Experimental Immunology 151 (1), 1-13, 2008 | 381 | 2008 |
Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis DP Gale, EG De Jorge, HT Cook, R Martinez-Barricarte, A Hadjisavvas, ... The Lancet 376 (9743), 794-801, 2010 | 375 | 2010 |
Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains MC Pickering, EG de Jorge, R Martinez-Barricarte, S Recalde, ... The Journal of experimental medicine 204 (6), 1249-1256, 2007 | 340 | 2007 |
Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32 J Esparza-Gordillo, EG Jorge, A Buil, LC Berges, M Lopez-Trascasa, ... Human Molecular Genetics 14 (5), 703-712, 2005 | 335 | 2005 |
Dimerization of complement factor H-related proteins modulates complement activation in vivo E Goicoechea de Jorge, JJE Caesar, TH Malik, M Patel, M Colledge, ... Proceedings of the National Academy of Sciences 110 (12), 4685-4690, 2013 | 304 | 2013 |
The interactive factor h–atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and factor I mutations with … RE Saunders, C Abarrategui‐Garrido, V Frémeaux‐Bacchi, ... Human mutation 28 (3), 222-234, 2007 | 196 | 2007 |
Factor H-related proteins determine complement-activating surfaces M Józsi, A Tortajada, B Uzonyi, EG de Jorge, SR de Córdoba Trends in immunology 36 (6), 374-384, 2015 | 164 | 2015 |
A hybrid CFHR3-1 gene causes familial C3 glomerulopathy TH Malik, PJ Lavin, EG de Jorge, KA Vernon, KL Rose, MP Patel, ... Journal of the American Society of Nephrology 23 (7), 1155-1160, 2012 | 154 | 2012 |
Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree J Esparza-Gordillo, EG de Jorge, CA Garrido, L Carreras, ... Molecular immunology 43 (11), 1769-1775, 2006 | 150 | 2006 |
The development of atypical hemolytic uremic syndrome depends on complement C5 EG de Jorge, P Macor, D Paixao-Cavalcante, KL Rose, F Tedesco, ... Journal of the American Society of Nephrology 22 (1), 137-145, 2011 | 132 | 2011 |
Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice F Fakhouri, EG De Jorge, F Brune, P Azam, HT Cook, MC Pickering Kidney international 78 (3), 279-286, 2010 | 124 | 2010 |
Acute presentation and persistent glomerulonephritis following streptococcal infection in a patient with heterozygous complement factor H–related protein 5 deficiency KA Vernon, EG De Jorge, AE Hall, V Fremeaux-Bacchi, TJ Aitman, ... American journal of kidney diseases 60 (1), 121-125, 2012 | 118 | 2012 |
Complement factor H binds to denatured rather than to native pentameric C-reactive protein S Hakobyan, CL Harris, CW Van Den Berg, MC Fernandez-Alonso, ... Journal of biological chemistry 283 (45), 30451-30460, 2008 | 118 | 2008 |
Elevated factor H–related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy A Tortajada, E Gutiérrez, EG de Jorge, J Anter, A Segarra, M Espinosa, ... Kidney international 92 (4), 953-963, 2017 | 109 | 2017 |
Factor H–related protein 5 interacts with pentraxin 3 and the extracellular matrix and modulates complement activation ÁI Csincsi, A Kopp, M Zöldi, Z Bánlaki, B Uzonyi, M Hebecker, JJE Caesar, ... The Journal of Immunology 194 (10), 4963-4973, 2015 | 94 | 2015 |
Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules S Johnson, L Tan, S van der Veen, J Caesar, E Goicoechea De Jorge, ... PLoS pathogens 8 (10), e1002981, 2012 | 73 | 2012 |
Genetic deficiency of complement factor H in a patient with age-related macular degeneration and membranoproliferative glomerulonephritis T Montes, EG de Jorge, R Ramos, M Gomà, O Pujol, P Sánchez-Corral, ... Molecular immunology 45 (10), 2897-2904, 2008 | 66 | 2008 |