| Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome SS Iyer, WP Pulskens, JJ Sadler, LM Butter, GJ Teske, TK Ulland, ... Proceedings of the National Academy of Sciences 106 (48), 20388-20393, 2009 | 822 | 2009 |
| Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney JC Leemans, G Stokman, N Claessen, KM Rouschop, GJD Teske, ... The Journal of clinical investigation 115 (10), 2894-2903, 2005 | 672 | 2005 |
| Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia S Knapp, JC Leemans, S Florquin, J Branger, NA Maris, J Pater, ... American journal of respiratory and critical care medicine 167 (2), 171-179, 2003 | 427 | 2003 |
| Role oftoll-like receptor 4 in gram-positive and gram-negative pneumonia inmice J Branger, S Knapp, S Weijer, JC Leemans, JM Pater, P Speelman, ... Infection and immunity 72 (2), 788-794, 2004 | 337 | 2004 |
| Sensing damage by the NLRP3 inflammasome JC Leemans, SL Cassel, FS Sutterwala Immunological reviews 243 (1), 152-162, 2011 | 323 | 2011 |
| Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury WP Pulskens, GJ Teske, LM Butter, JJ Roelofs, T Van Der Poll, S Florquin, ... PloS one 3 (10), e3596, 2008 | 304 | 2008 |
| Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice JC Leemans, NP Juffermans, S Florquin, N van Rooijen, ... The journal of immunology 166 (7), 4604-4611, 2001 | 278 | 2001 |
| Hydrogen sulfide-induced hypometabolism prevents renal ischemia/reperfusion injury EM Bos, HGD Leuvenink, PM Snijder, NJ Kloosterhuis, JL Hillebrands, ... Journal of the American Society of Nephrology 20 (9), 1901-1905, 2009 | 215 | 2009 |
| TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives A Tammaro, M Derive, S Gibot, JC Leemans, S Florquin, MC Dessing Pharmacology & therapeutics 177, 81-95, 2017 | 211 | 2017 |
| Toll‐like receptor 4 plays a protective role in pulmonary tuberculosis in mice J Branger, JC Leemans, S Florquin, S Weijer, P Speelman, T Van Der Poll International immunology 16 (3), 509-516, 2004 | 185 | 2004 |
| Pattern recognition receptors and the inflammasome in kidney disease JC Leemans, L Kors, HJ Anders, S Florquin Nature Reviews Nephrology 10 (7), 398-414, 2014 | 183 | 2014 |
| TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury WP Pulskens, E Rampanelli, GJ Teske, LM Butter, N Claessen, IK Luirink, ... Journal of the American Society of Nephrology 21 (8), 1299-1308, 2010 | 183 | 2010 |
| CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis JC Leemans, S Florquin, M Heikens, ST Pals, R Van der Neut, ... The Journal of clinical investigation 111 (5), 681-689, 2003 | 164 | 2003 |
| Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice CW Wieland, S Florquin, ED Chan, JC Leemans, S Weijer, A Verbon, ... International immunology 17 (11), 1399-1408, 2005 | 158 | 2005 |
| The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury JC Leemans, LM Butter, WPC Pulskens, GJD Teske, N Claessen, ... PloS one 4 (5), e5704, 2009 | 152 | 2009 |
| The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense JC Leemans, AA te Velde, S Florquin, RJ Bennink, K de Bruin, ... The Journal of Immunology 172 (2), 1125-1131, 2004 | 150 | 2004 |
| Ventilator-induced lung injury is mediated by the NLRP3 inflammasome MT Kuipers, H Aslami, JR Janczy, KF van der Sluijs, APJ Vlaar, ... The Journal of the American Society of Anesthesiologists 116 (5), 1104-1115, 2012 | 145 | 2012 |
| Differential role of interleukin-6 in lung inflammation induced by lipoteichoic acid and peptidoglycan from Staphylococcus aureus JC Leemans, MJBM Vervoordeldonk, S Florquin, KP van Kessel, ... American journal of respiratory and critical care medicine 165 (10), 1445-1450, 2002 | 139 | 2002 |
| Depletion of gut microbiota protects against renal ischemia-reperfusion injury D Emal, E Rampanelli, I Stroo, LM Butter, GJ Teske, N Claessen, ... Journal of the American Society of Nephrology 28 (5), 1450-1461, 2017 | 130 | 2017 |
| Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury JJTH Roelofs, KMA Rouschop, JC Leemans, N Claessen, AM de Boer, ... Journal of the American society of nephrology 17 (1), 131-140, 2006 | 129 | 2006 |
