| Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective W Lewis, BJ Day, WC Copeland Nature reviews Drug discovery 2 (10), 812-822, 2003 | 678 | 2003 |
| Mitochondrial DNA in human malignancy JS Penta, FM Johnson, JT Wachsman, WC Copeland Mutation Research/Reviews in Mutation Research 488 (2), 119-133, 2001 | 621 | 2001 |
| Eukaryotic DNA polymerases: proposal for a revised nomenclature PMJ Burgers, EV Koonin, E Bruford, L Blanco, KC Burtis, MF Christman, ... Journal of Biological Chemistry 276 (47), 43487-43490, 2001 | 418 | 2001 |
| Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase γ PA Ropp, WC Copeland Genomics 36 (3), 449-458, 1996 | 375 | 1996 |
| DNA polymerase γ in mitochondrial DNA replication and repair MA Graziewicz, MJ Longley, WC Copeland Chemical reviews 106 (2), 383-405, 2006 | 352 | 2006 |
| Molecular and clinical genetics of mitochondrial diseases due to POLG mutations LJC Wong, RK Naviaux, N Brunetti‐Pierri, Q Zhang, ES Schmitt, C Truong, ... Human mutation 29 (9), E150-E172, 2008 | 336 | 2008 |
| Inherited mitochondrial diseases of DNA replication WC Copeland Annu. Rev. Med. 59 (1), 131-146, 2008 | 326 | 2008 |
| POLG-related disorders and their neurological manifestations S Rahman, WC Copeland Nature Reviews Neurology 15 (1), 40-52, 2019 | 314 | 2019 |
| The fidelity of human DNA polymerase γ with and without exonucleolytic proofreading and the p55 accessory subunit MJ Longley, D Nguyen, TA Kunkel, WC Copeland Journal of Biological Chemistry 276 (42), 38555-38562, 2001 | 302 | 2001 |
| The mitochondrial p55 accessory subunit of human DNA polymerase γ enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance SE Lim, MJ Longley, WC Copeland Journal of Biological Chemistry 274 (53), 38197-38203, 1999 | 291 | 1999 |
| Mutant POLG2 disrupts DNA polymerase γ subunits and causes progressive external ophthalmoplegia MJ Longley, S Clark, CYW Man, G Hudson, SE Durham, RW Taylor, ... The American Journal of Human Genetics 78 (6), 1026-1034, 2006 | 286 | 2006 |
| Mitochondrial DNA alterations in cancer WC Copeland, JT Wachsman, FM Johnson, JS Penta Cancer investigation 20 (4), 557-569, 2002 | 283 | 2002 |
| Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase γ SE Lim, WC Copeland Journal of Biological Chemistry 276 (26), 23616-23623, 2001 | 282 | 2001 |
| Identification of 5′-deoxyribose phosphate lyase activity in human DNA polymerase γ and its role in mitochondrial base excision repair in vitro MJ Longley, R Prasad, DK Srivastava, SH Wilson, WC Copeland Proceedings of the National Academy of Sciences 95 (21), 12244-12248, 1998 | 280 | 1998 |
| Mitochondria, energetics, epigenetics, and cellular responses to stress DT Shaughnessy, K McAllister, L Worth, AC Haugen, JN Meyer, ... Environmental health perspectives 122 (12), 1271-1278, 2014 | 261 | 2014 |
| DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity S Song, ZF Pursell, WC Copeland, MJ Longley, TA Kunkel, CK Mathews Proceedings of the National Academy of Sciences 102 (14), 4990-4995, 2005 | 244 | 2005 |
| The mitochondrial DNA polymerase as a target of oxidative damage MA Graziewicz, BJ Day, WC Copeland Nucleic acids research 30 (13), 2817-2824, 2002 | 241 | 2002 |
| The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. P Park, W Copeland, L Yang, T Wang, MR Botchan, IJ Mohr Proceedings of the National Academy of Sciences 91 (18), 8700-8704, 1994 | 223 | 1994 |
| Site-specific somatic mitochondrial DNA point mutations in patients with thymidine phosphorylase deficiency Y Nishigaki, R Martí, WC Copeland, M Hirano The Journal of clinical investigation 111 (12), 1913-1921, 2003 | 220 | 2003 |
| DNA polymerase gamma and mitochondrial disease: understanding the consequence of POLG mutations SSL Chan, WC Copeland Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (5), 312-319, 2009 | 216 | 2009 |
