Nuclear inclusion bodies of mutant and wild‐type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation F De Smet, M Saiz Rubio, D Hompes, E Naus, G De Baets, T Langenberg, ... The Journal of pathology 242 (1), 24-38, 2017 | 60 | 2017 |
Thermodynamic and evolutionary coupling between the native and amyloid state of globular proteins T Langenberg, R Gallardo, R van der Kant, N Louros, E Michiels, ... Cell reports 31 (2), 2020 | 38 | 2020 |
Reverse engineering synthetic antiviral amyloids E Michiels, K Roose, R Gallardo, L Khodaparast, L Khodaparast, ... Nature communications 11 (1), 2832, 2020 | 36 | 2020 |
Autonomous aggregation suppression by acidic residues explains why chaperones favour basic residues B Houben, E Michiels, M Ramakers, K Konstantoulea, N Louros, ... The EMBO journal 39 (11), e102864, 2020 | 32 | 2020 |
Heterotypic Amyloid β interactions facilitate amyloid assembly and modify amyloid structure K Konstantoulea, P Guerreiro, M Ramakers, N Louros, LD Aubrey, ... The EMBO journal 41 (2), e108591, 2022 | 26 | 2022 |
The cellular modifier MOAG‐4/SERF drives amyloid formation through charge complementation A Pras, B Houben, FA Aprile, R Seinstra, R Gallardo, L Janssen, ... The EMBO Journal 40 (21), e107568, 2021 | 18 | 2021 |
Protein structure and aggregation: a marriage of necessity ruled by aggregation gatekeepers B Houben, F Rousseau, J Schymkowitz Trends in Biochemical Sciences 47 (3), 194-205, 2022 | 14 | 2022 |
Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins G Wu, L Khodaparast, L Khodaparast, M De Vleeschouwer, J Housmans, ... Cell Chemical Biology 28 (4), 524-536. e4, 2021 | 14 | 2021 |
Differential proteostatic regulation of insoluble and abundant proteins R Ramakrishnan, B Houben, F Rousseau, J Schymkowitz Bioinformatics 35 (20), 4098-4107, 2019 | 9 | 2019 |
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V F Claes, S Rudyak, AS Laird, N Louros, J Beerten, M Debulpaep, ... Protein Engineering, Design and Selection 32 (10), 443-457, 2019 | 6 | 2019 |
Gene erosion can lead to gain-of-function alleles that contribute to bacterial fitness J Mortier, E Gayán, R Van Eyken, OE Torres Montaguth, L Khodaparast, ... Mbio 12 (4), 10.1128/mbio. 01129-21, 2021 | 5 | 2021 |
Protein Homeostasis Database: protein quality control in E.coli R Ramakrishnan, B Houben, Ł Kreft, A Botzki, J Schymkowitz, ... Bioinformatics 36 (3), 948-949, 2020 | 3 | 2020 |
Heterotypic Aβ interactions facilitate amyloid assembly and modify amyloid structure K Konstantoulea, P Guerreiro, M Ramakers, N Louros, L Aubrey, ... bioRxiv, 2021.04. 28.441786, 2021 | 1 | 2021 |
The role of charges in protein folding, aggregation and homeostasis B Houben | | 2020 |
Preliminary study for the identification of SERF2-interacting proteins using a Virotrap screening approach A Pras, B Houben, J Schymkowitz, F Rousseau, S Eyckerman, E Nollen The Molecular Role of SERF in Amyloid Formation, 111, 0 | | |