Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity M Coccia, C Collignon, C Hervé, A Chalon, I Welsby, S Detienne, ... npj Vaccines 2 (1), 25, 2017 | 199 | 2017 |
Liposomes containing monophosphoryl lipid A and QS-21 serve as an effective adjuvant for soluble circumsporozoite protein malaria vaccine FMP013 CJ Genito, Z Beck, TW Phares, F Kalle, KJ Limbach, ME Stefaniak, ... Vaccine 35 (31), 3865-3874, 2017 | 65 | 2017 |
Considerations for size, surface charge, polymer degradation, co‐delivery, and manufacturability in the development of polymeric particle vaccines for infectious diseases CJ Genito, CJ Batty, EM Bachelder, KM Ainslie Advanced nanobiomed research 1 (3), 2000041, 2021 | 44 | 2021 |
Safety, toxicity and immunogenicity of a malaria vaccine based on the circumsporozoite protein (FMP013) with the adjuvant army liposome formulation containing QS21 (ALFQ) A Cawlfield, CJ Genito, Z Beck, ES Bergmann-Leitner, AA Bitzer, K Soto, ... Vaccine 37 (29), 3793-3803, 2019 | 42 | 2019 |
Optimization of a Plasmodium falciparum circumsporozoite protein repeat vaccine using the tobacco mosaic virus platform MD Langowski, FA Khan, AA Bitzer, CJ Genito, AJ Schrader, ML Martin, ... Proceedings of the National Academy of Sciences 117 (6), 3114-3122, 2020 | 33 | 2020 |
Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes TW Phares, AD May, CJ Genito, NA Hoyt, FA Khan, MD Porter, M DeBot, ... Malaria journal 16, 1-12, 2017 | 21 | 2017 |
Injectable, ribbon-like microconfetti biopolymer platform for vaccine applications KM Moore, CJ Batty, RT Stiepel, CJ Genito, EM Bachelder, KM Ainslie ACS applied materials & interfaces 12 (35), 38950-38961, 2020 | 19 | 2020 |
A predictive mechanistic model of drug release from surface eroding polymeric nanoparticles RT Stiepel, ES Pena, SA Ehrenzeller, MD Gallovic, LM Lifshits, CJ Genito, ... Journal of controlled release 351, 883-895, 2022 | 18 | 2022 |
Dexamethasone and fumaric acid ester conjugate synergistically inhibits inflammation and NF-κB in macrophages CJ Genito, M Eckshtain-Levi, ZL Piedra-Quintero, SA Krovi, A Kroboth, ... Bioconjugate chemistry 32 (8), 1629-1640, 2021 | 14 | 2021 |
Protective antibody threshold of RTS, S/AS01 malaria vaccine correlates antigen and adjuvant dose in mouse model CJ Genito, K Brooks, A Smith, E Ryan, K Soto, Y Li, L Warter, S Dutta npj Vaccines 8 (1), 114, 2023 | 3 | 2023 |
Triple threat: how diabetes results in worsened bacterial infections BP Darwitz, CJ Genito, LR Thurlow Infection and Immunity, e00509-23, 2024 | 1 | 2024 |
Hyperglycemia potentiates increased Staphylococcus aureus virulence and resistance to growth inhibition by Pseudomonas aeruginosa CJ Genito, BP Darwitz, MA Greenwald, MC Wolfgang, LR Thurlow Microbiology Spectrum 11 (6), e02299-23, 2023 | 1 | 2023 |
mTOR signaling is required for phagocyte free radical production, GLUT1 expression, and control of Staphylococcus aureus infection CJ Genito, BP Darwitz, CP Reber, NJ Moorman, CL Graves, AJ Monteith, ... Mbio 15 (6), e00862-24, 2024 | | 2024 |
Impaired mTOR Signaling Causes Immune Suppression in Diabetes CJ Genito, B Darwitz, LR Thurlow The Journal of Immunology 210 (1_Supplement), 160.04-160.04, 2023 | | 2023 |
Generation of Immune Tolerance with Combined Pharmacological Agents CJ Genito The University of North Carolina at Chapel Hill, 2021 | | 2021 |
Combining tolerogenic agents with dexamethasone synergistically inhibits innate inflammatory responses CJ Genito, RT Stiepel, CJ Batty, EM Bachelder, KM Ainslie The Journal of Immunology 204 (1_Supplement), 238.18-238.18, 2020 | | 2020 |
EFFECT OF DELAYED AND FRACTIONAL DOSING ON THE TITERS, FINE SPECIFICITY, AVIDITY AND BIOLOGICAL ACTIVITY OF RHESUS ANTIBODIES AGAINST A CIRCUMSPOROZOITE PROTEIN BASED VACCINE … S Dutta, A Cawlfield, C Genito, Z Beck, A Bitzer, E Leitner, R Gerbasi, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 99 (4), 468-468, 2018 | | 2018 |
PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN ADJUVANTED WITH LIPOSOMAL ADJUVANT INDUCES HIGHLY PROTECTIVE RESPONSES IN C57BL/6 MICE AGAINST TRANSGENIC PARASITE CHALLENGE CJ Genito, Z Beck, TW Phares, F Kalle, GR Matyas, CR Alving, NC Waters, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 95 (5), 514-515, 2017 | | 2017 |
A Predictive Mechanistic Model of Drug Release from Acetalated Dextran Particles RT Stiepel, ES Pena, MD Gallovic, CJ Genito, EM Bachelder, KM Ainslie | | |