A mitosis-specific and R loop–driven ATR pathway promotes faithful chromosome segregation L Kabeche, HD Nguyen, R Buisson, L Zou Science 359 (6371), 108-114, 2018 | 281 | 2018 |
Regulation of kinetochore–microtubule attachments through homeostatic control during mitosis KM Godek, L Kabeche, DA Compton Nature Reviews Molecular Cell Biology 16 (1), 57-64, 2015 | 179 | 2015 |
DNA-damage response during mitosis induces whole-chromosome missegregation SF Bakhoum, L Kabeche, JP Murnane, BI Zaki, DA Compton Cancer discovery 4 (11), 1281-1289, 2014 | 165 | 2014 |
Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation L Kabeche, DA Compton Nature 502 (7469), 110-113, 2013 | 156 | 2013 |
Genomic instability is induced by persistent proliferation of cells undergoing epithelial-to-mesenchymal transition V Comaills, L Kabeche, R Morris, R Buisson, M Yu, MW Madden, ... Cell reports 17 (10), 2632-2647, 2016 | 129 | 2016 |
Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore–microtubule attachments ARR Maia, Z Garcia, L Kabeche, M Barisic, S Maffini, S Macedo-Ribeiro, ... Journal of Cell Biology 199 (2), 285-301, 2012 | 102 | 2012 |
Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells L Kabeche, DA Compton Current biology 22 (7), 638-644, 2012 | 94 | 2012 |
Numerical chromosomal instability mediates susceptibility to radiation treatment SF Bakhoum, L Kabeche, MD Wood, CD Laucius, D Qu, AM Laughney, ... Nature communications 6 (1), 5990, 2015 | 84 | 2015 |
Mitotic DNA damage response: at the crossroads of structural and numerical cancer chromosome instabilities SF Bakhoum, L Kabeche, DA Compton, SN Powell, H Bastians Trends in cancer 3 (3), 225-234, 2017 | 82 | 2017 |
Shugoshin-1 balances Aurora B kinase activity via PP2A to promote chromosome bi-orientation A Meppelink, L Kabeche, MJM Vromans, DA Compton, SMA Lens Cell reports 11 (4), 508-515, 2015 | 69 | 2015 |
STAG2 promotes error correction in mitosis by regulating kinetochore–microtubule attachments M Kleyman, L Kabeche, DA Compton Journal of cell science 127 (19), 4225-4233, 2014 | 42 | 2014 |
A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase SN Cullati, L Kabeche, AN Kettenbach, SA Gerber Journal of Cell Biology 216 (8), 2339-2354, 2017 | 33 | 2017 |
DNA-damage response during mitosis induces whole-chromosome missegregation. Cancer Discov. 2014; 4: 1281–1289. doi: 10.1158/2159-8290 SF Bakhoum, L Kabeche, JP Murnane, BI Zaki, DA Compton CD-14-0403.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 17 | |
ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei YK Joo, EM Black, I Trier, W Haakma, L Zou, L Kabeche Molecular Cell 83 (20), 3642-3658. e4, 2023 | 8 | 2023 |
ATR protects centromere identity by promoting DAXX association with PML nuclear bodies I Trier, EM Black, YK Joo, L Kabeche Cell Reports 42 (5), 2023 | 4 | 2023 |
Molecular mechanism of hyperactivation conferred by a truncation of TRPA1 A Bali, SP Schaefer, I Trier, AL Zhang, L Kabeche, CE Paulsen Nature Communications 14 (1), 2867, 2023 | 3 | 2023 |
A painful paradox: How a drastic TRPA1 truncation confers gain-of-function A Bali, S Schaefer, I Trier, AL Zhang, L Kabeche, CE Paulsen Biophysical Journal 123 (3), 37a, 2024 | | 2024 |
Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation EM Black, CA Ramirez Parrado, I Trier, WV Li, YK Joo, J Pichurin, Y Liu, ... bioRxiv, 2024.03. 08.584115, 2024 | | 2024 |
Keeping RelApse in Chk: molecular mechanisms of Chk1 inhibitor resistance in lymphoma EM Black, YK Joo, L Kabeche Biochemical Journal 479 (22), 2345-2349, 2022 | | 2022 |
Molecular Mechanism of Hyperactivation Conferred by a Truncated TRPA1 Disease Mutant Suggests New Gating Insights A Bali, SP Schaefer, I Trier, AL Zhang, L Kabeche, CE Paulsen bioRxiv, 2022.01. 05.475133, 2022 | | 2022 |