PTPN 2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours F Wiede, KH Lu, X Du, S Liang, K Hochheiser, GT Dodd, PK Goh, ... The EMBO journal 39 (2), e103637, 2020 | 107 | 2020 |
PTP1B is an intracellular checkpoint that limits T-cell and CAR T-cell antitumor immunity F Wiede, KH Lu, X Du, MN Zeissig, R Xu, PK Goh, CE Xirouchaki, ... Cancer discovery 12 (3), 752-773, 2022 | 82 | 2022 |
Baicalin attenuates inflammation in mice with OVA-induced asthma by inhibiting NF-κB and suppressing CCR7/CCL19/CCL21 J Liu, Y Wei, Q Luo, F Xu, Z Zhao, H Zhang, L Lu, J Sun, F Liu, X Du, M Li, ... International Journal of Molecular Medicine 38 (5), 1541-1548, 2016 | 68 | 2016 |
Ligustrazine attenuates inflammation and the associated chemokines and receptors in ovalbumine-induced mouse asthma model Y Wei, J Liu, H Zhang, X Du, Q Luo, J Sun, F Liu, M Li, F Xu, K Wei, ... Environmental Toxicology and Pharmacology 46, 55-61, 2016 | 35 | 2016 |
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity S Liang, E Tran, X Du, J Dong, H Sudholz, H Chen, Z Qu, ND Huntington, ... Nature Communications 14 (1), 4524, 2023 | 32 | 2023 |
A histone deacetylase inhibitor, panobinostat, enhances chimeric antigen receptor T-cell antitumor effect against pancreatic cancer AI Ali, M Wang, B von Scheidt, PM Dominguez, AJ Harrison, DGM Tantalo, ... Clinical Cancer Research 27 (22), 6222-6234, 2021 | 22 | 2021 |
BuShenYiQi granule inhibits atopic dermatitis via improving central and skin hypothalamic-pituitary-adrenal axis function L Kong, J Wu, Y Lin, G Wang, J Wang, J Liu, M Chen, X Du, J Sun, J Lin, ... PLoS One 10 (2), e0116427, 2015 | 15 | 2015 |
Enhancing co-stimulation of CAR T cells to improve treatment outcomes in solid cancers AJ Harrison, X Du, B von Scheidt, MH Kershaw, CY Slaney Immunotherapy Advances 1 (1), ltab016, 2021 | 12 | 2021 |
Targeting protein tyrosine phosphatase 22 does not enhance the efficacy of chimeric antigen receptor T cells in solid tumors X Du, PK Darcy, F Wiede, T Tiganis Molecular and Cellular Biology, 2022 | 9 | 2022 |
Abstract PR04: CRISPR-mediated PTPN2 deletion in car T cells enhances anti-tumor efficacy X Du, F Wiede, PK Darcy, T Tiganis Cancer Immunology Research 10 (1_Supplement), PR04-PR04, 2022 | 1 | 2022 |