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Michael Nagle
Michael Nagle
Director, Head of Human Genetics, Eisai, Inc
在 eisai.com 的电子邮件经过验证
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引用次数
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Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
CL Hyde, MW Nagle, C Tian, X Chen, SA Paciga, JR Wendland, JY Tung, ...
Nature genetics 48 (9), 1031-1036, 2016
7702016
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ...
Nature communications 11 (1), 163, 2020
5622020
A genome-wide association study of pulmonary function measures in the Framingham Heart Study
JB Wilk, T Chen, DJ Gottlieb, RE Walter, MW Nagle, BJ Brandler, ...
PLoS genetics 5 (3), e1000429, 2009
3892009
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ...
Nature metabolism 2 (10), 1135-1148, 2020
3852020
Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer’s disease
CD Whelan, N Mattsson, MW Nagle, S Vijayaraghavan, C Hyde, ...
Acta neuropathologica communications 7, 1-14, 2019
1872019
Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells
JR Kraehling, JH Chidlow, C Rajagopal, MG Sugiyama, JW Fowler, ...
Nature communications 7 (1), 13516, 2016
1552016
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: The GenePD Study
JE Tobin, JC Latourelle, MF Lew, C Klein, O Suchowersky, HA Shill, ...
Neurology 71 (1), 28-34, 2008
1482008
The Gly2019Ser mutation in LRRK2is not fully penetrant in familial Parkinson's disease: the GenePD study
JC Latourelle, M Sun, MF Lew, O Suchowersky, C Klein, LI Golbe, ...
BMC medicine 6, 1-7, 2008
1202008
Replication of association between ELAVL4 and Parkinson disease: the GenePD study
AL DeStefano, J Latourelle, MF Lew, O Suchowersky, C Klein, LI Golbe, ...
Human genetics 124, 95-99, 2008
522008
Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension
LJ Song, X Chen, TA Swanson, B LaViolette, J Pang, T Cunio, MW Nagle, ...
Elife 9, e58376, 2020
342020
GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci
AV Jones, M Tilley, A Gutteridge, C Hyde, M Nagle, D Ziemek, D Gorman, ...
Human molecular genetics 26 (7), 1391-1406, 2017
342017
The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane
MW Nagle, JC Latourelle, A Labadorf, A Dumitriu, TC Hadzi, TG Beach, ...
PloS one 11 (8), e0160925, 2016
272016
Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; The NHLBI Family Heart Study
JM Laramie, JB Wilk, SL Williamson, MW Nagle, JC Latourelle, JE Tobin, ...
BMC medical genetics 9, 1-9, 2008
262008
Multiple genes influence BMI on chromosome 7q31–34: the NHLBI Family Heart Study
JM Laramie, JB Wilk, SL Williamson, MW Nagle, JC Latourelle, JE Tobin, ...
Obesity 17 (12), 2182-2189, 2009
192009
The genetic regulation of protein expression in cerebrospinal fluid
O Hansson, A Kumar, S Janelidze, E Stomrud, PS Insel, K Blennow, ...
EMBO Molecular Medicine 15 (1), e16359, 2023
172023
Genomic evaluation of circulating proteins for drug target characterisation and precision medicine
L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ...
BioRxiv, 2020.04. 03.023804, 2020
142020
The genomics of heart failure: design and rationale of the HERMES consortium
RT Lumbers, S Shah, H Lin, T Czuba, A Henry, DI Swerdlow, A Mälarstig, ...
ESC Heart Failure 8 (6), 5531-5541, 2021
122021
NYD-SP18 is associated with obesity in the NHLBI Family Heart Study
JB Wilk, JM Laramie, JC Latourelle, S Williamson, MW Nagle, JE Tobin, ...
International journal of obesity 32 (6), 930-935, 2008
112008
Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease
M Ali, DB Archer, P Gorijala, D Western, J Timsina, MV Fernández, ...
Acta neuropathologica communications 11 (1), 68, 2023
92023
Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure
S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ...
bioRxiv, 682013, 2019
72019
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