Chalcones with electron-withdrawing and electron-donating substituents: anticancer activity against TRAIL resistant cancer cells, structure–activity relationship analysis and … CW Mai, M Yaeghoobi, N Abd-Rahman, YB Kang, MR Pichika European Journal of Medicinal Chemistry 77, 378-387, 2014 | 175 | 2014 |
Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment CK Looi, FFL Chung, CO Leong, SF Wong, R Rosli, CW Mai Journal of Experimental & Clinical Cancer Research 38, 1-23, 2019 | 152 | 2019 |
Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers CW Mai, YB Kang, MR Pichika OncoTargets and therapy, 1573-1587, 2013 | 146 | 2013 |
6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ) BS Tan, O Kang, CW Mai, KH Tiong, ASB Khoo, MR Pichika, ... Cancer letters 336 (1), 127-139, 2013 | 112 | 2013 |
Mechanisms Underlying the Anti-Inflammatory Effects of Clinacanthus nutans Lindau Extracts: Inhibition of Cytokine Production and Toll-Like Receptor-4 Activation CW Mai, KSI Yap, MT Kho, NH Ismail, K Yusoff, K Shaari, SY Chin, ... Frontiers in pharmacology 7, 7, 2016 | 89 | 2016 |
Functional roles of JNK and p38 MAPK signaling in nasopharyngeal carcinoma LJW Pua, CW Mai, FFL Chung, ASB Khoo, CO Leong, WM Lim, LW Hii International journal of molecular sciences 23 (3), 1108, 2022 | 88 | 2022 |
Additivity vs. synergism: Investigation of the additive interaction of cinnamon bark oil and meropenem in combinatory therapy SK Yang, K Yusoff, CW Mai, WM Lim, WS Yap, SHE Lim, KS Lai Molecules 22 (11), 1733, 2017 | 74 | 2017 |
Cudraflavone C induces tumor-specific apoptosis in colorectal cancer cells through inhibition of the phosphoinositide 3-kinase (PI3K)-AKT pathway HC Soo, FFL Chung, KH Lim, VA Yap, TD Bradshaw, LW Hii, SH Tan, ... PLoS One 12 (1), e0170551, 2017 | 73 | 2017 |
Plant-derived antimicrobials: Insights into mitigation of antimicrobial resistance SK Yang, LY Low, PSX Yap, K Yusoff, CW Mai, KS Lai, SHE Lim Records of Natural Products 12 (4), 295-316, 2018 | 62 | 2018 |
Targeting legumain as a novel therapeutic strategy in cancers CW Mai, FFL Chung, CO Leong Current Drug Targets 18 (11), 1259-1268, 2017 | 59 | 2017 |
The role of Ras-associated protein 1 (Rap1) in cancer: bad actor or good player? CK Looi, LW Hii, SC Ngai, CO Leong, CW Mai Biomedicines 8 (9), 334, 2020 | 58 | 2020 |
Global antimicrobial stewardship: a closer look at the formidable implementation challenges JJL Tiong, JSE Loo, CW Mai Frontiers in microbiology 7, 1860, 2016 | 55 | 2016 |
Recent emergence of rhenium (I) tricarbonyl complexes as photosensitisers for cancer therapy HS Liew, CW Mai, M Zulkefeli, T Madheswaran, LV Kiew, N Delsuc, ... Molecules 25 (18), 4176, 2020 | 53 | 2020 |
Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1) FFL Chung, PFTM Tan, VJ Raja, BS Tan, KH Lim, TS Kam, LW Hii, ... Scientific Reports 7 (1), 42504, 2017 | 52 | 2017 |
Molecular hybrids integrated with benzimidazole and pyrazole structural motifs: Design, synthesis, biological evaluation, and molecular docking studies R Sivaramakarthikeyan, S Iniyaval, V Saravanan, WM Lim, CW Mai, ... ACS omega 5 (17), 10089-10098, 2020 | 48 | 2020 |
Challenges and opportunities of nanotechnology as delivery platform for tocotrienols in cancer therapy G Maniam, CW Mai, M Zulkefeli, C Dufès, DMY Tan, JY Fu Frontiers in pharmacology 9, 1358, 2018 | 45 | 2018 |
A bis-benzopyrroloisoquinoline alkaloid incorporating a cyclobutane core and a chlorophenanthroindolizidine alkaloid with cytotoxic activity from Ficus fistulosa var. tengerensis AAQ Al-Khdhairawi, P Krishnan, CW Mai, FFL Chung, CO Leong, ... Journal of natural products 80 (10), 2734-2740, 2017 | 45 | 2017 |
Potential of superhydrophobic surface for blood-contacting medical devices XH Wu, YK Liew, CW Mai, YY Then International journal of molecular sciences 22 (7), 3341, 2021 | 43 | 2021 |
Identification of inhibitors synergizing gemcitabine sensitivity in the squamous subtype of pancreatic ductal adenocarcinoma (PDAC) JL Er, PN Goh, CY Lee, YJ Tan, LW Hii, CW Mai, FFL Chung, CO Leong Apoptosis 23, 343-355, 2018 | 42 | 2018 |
Histone deacetylase (HDAC) inhibitors and doxorubicin combinations target both breast cancer stem cells and non-stem breast cancer cells simultaneously LW Hii, FFL Chung, JSS Soo, BS Tan, CW Mai, CO Leong Breast Cancer Research and Treatment 179, 615-629, 2020 | 39 | 2020 |