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John C. Thomas
John C. Thomas
Bioinformatics scientist, University of Cambridge
在 cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance
AR Bowden, DA Morales-Juarez, M Sczaniecka-Clift, MM Agudo, ...
Elife 9, e55325, 2020
432020
Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens
SW Awwad, A Serrano-Benitez, JC Thomas, V Gupta, SP Jackson
Nature Reviews Molecular Cell Biology 24 (7), 477-494, 2023
342023
Loss of cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress
RL Lloyd, V Urban, F Muñoz-Martínez, I Ayestaran, JC Thomas, ...
Nucleic acids research 49 (15), 8665-8683, 2021
292021
Isolation and characterization of metaldehyde‐degrading bacteria from domestic soils
JC Thomas, T Helgason, CJ Sinclair, JWB Moir
Microbial Biotechnology 10 (6), 1824-1829, 2017
232017
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling
D Sun, O Llora Batlle, J van den Ameele, JC Thomas, P He, K Lim, ...
The EMBO Journal 41 (21), e111338, 2022
192022
Genomic basis for pesticide degradation revealed by selection, isolation and characterisation of a library of metaldehyde-degrading strains from soil
V Castro-Gutiérrez, E Fuller, JC Thomas, CJ Sinclair, S Johnson, ...
Soil Biology and Biochemistry 142, 107702, 2020
172020
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity
A Serrano‐Benitez, SE Wells, L Drummond‐Clarke, LC Russo, ...
The EMBO Journal 42 (18), e113190, 2023
82023
An organoid CRISPRi screen revealed that SOX9 primes human fetal lung tip progenitors to receive WNT and RTK signals
D Sun, OL Batlle, J van den Ameele, JC Thomas, P He, K Lim, W Tang, ...
BioRxiv, 2022.01. 27.478034, 2022
42022
RAD54L2 counters TOP2-DNA adducts to promote genome stability
G D’Alessandro, DA Morales-Juarez, SL Richards, KC Nitiss, ...
Science Advances 9 (49), eadl2108, 2023
32023
The molecular basis for the biotic degradation of metaldehyde
JC Thomas
University of York, 2016
32016
Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens
S Lam, JC Thomas, SP Jackson
bioRxiv, 2024.01. 14.575203, 2024
2024
RAD54L2 mediates a novel mechanism to counter TOP2-DNA adducts
G D'Alessandro, D Morales-Juarez, S Richards, A Serrano-Benitez, ...
American Association for the Advancement of Science, 2023
2023
Nurturing a revolution in DNA repair and cancer therapy through CRISPR–Cas screens
S Awwad, A Serrano-Benitez, J Thomas, V Gupta, S Jackson
Springer Nature, 2023
2023
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