关注
Toshifumi Yokota, PhD, FCAHS
Toshifumi Yokota, PhD, FCAHS
Professor, Garrett Cumming Muscular Dystrophy Canada Research Chair, University of Alberta
在 ualberta.ca 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Eteplirsen in the treatment of Duchenne muscular dystrophy
KR Lim, R Maruyama, T Yokota
Drug Design, Development and Therapy 11, 533-545, 2017
1294*2017
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles
QL Lu, A Rabinowitz, YC Chen, T Yokota, HF Yin, J Alter, A Jadoon, ...
Proceedings of the National Academy of Sciences 102 (1), 198-203, 2005
4902005
Efficacy of systemic morpholino exon‐skipping in Duchenne dystrophy dogs
T Yokota, Q Lu, T Partridge, M Kobayashi, A Nakamura, S Takeda, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
4852009
Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy
M Taniguchi-Ikeda, K Kobayashi, M Kanagawa, C Yu, K Mori, T Oda, ...
Nature 478 (7367), 127-131, 2011
2022011
Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery
Y Aoki, T Yokota, T Nagata, A Nakamura, J Tanihata, T Saito, ...
Proceedings of the National Academy of Sciences 109 (34), 13763-13768, 2012
1882012
Restoring dystrophin expression in duchenne muscular dystrophy muscle: progress in exon skipping and stop codon read through
EP Hoffman, A Bronson, AA Levin, S Takeda, T Yokota, AR Baudy, ...
The American journal of pathology 179 (1), 12-22, 2011
1742011
Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene
M Sakamoto, K Yuasa, M Yoshimura, T Yokota, T Ikemoto, M Suzuki, ...
Biochemical and biophysical research communications 293 (4), 1265-1272, 2002
1522002
In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52–deficient mdx mouse
Y Aoki, A Nakamura, T Yokota, T Saito, H Okazawa, T Nagata, S Takeda
Molecular Therapy 18 (11), 1995-2005, 2010
1482010
α1-Syntrophin modulates turnover of ABCA1
Y Munehira, T Ohnishi, S Kawamoto, A Furuya, K Shitara, M Imamura, ...
Journal of Biological Chemistry 279 (15), 15091-15095, 2004
1332004
The status of exon skipping as a therapeutic approach to duchenne muscular dystrophy
QL Lu, T Yokota, S Takeda, L Garcia, F Muntoni, T Partridge
Molecular Therapy 19 (1), 9-15, 2011
1252011
Expansion of revertant fibers in dystrophic mdx muscles reflects activity of muscle precursor cells and serves as an index of muscle regeneration
T Yokota, QL Lu, JE Morgan, KE Davies, R Fisher, S Takeda, TA Partridge
Journal of cell science 119 (13), 2679-2687, 2006
1102006
Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy
Y Echigoya, A Nakamura, T Nagata, N Urasawa, KRQ Lim, N Trieu, ...
Proceedings of the National Academy of Sciences 114 (16), 4213-4218, 2017
1062017
Restoring Dystrophin Expression in Duchenne Muscular Dystrophy: Current Status of Therapeutic Approaches
Y Shimizu-Motohashi, H Komaki, N Motohashi, S Takeda, T Yokota, ...
Journal of Personalized Medicine 9 (1), 1, 2019
1032019
α1-Syntrophin–deficient skeletal muscle exhibits hypertrophy and aberrant formation of neuromuscular junctions during regeneration
Y Hosaka, T Yokota, Y Miyagoe-Suzuki, K Yuasa, M Imamura, R Matsuda, ...
The Journal of cell biology 158 (6), 1097-1107, 2002
942002
Optimizing exon skipping therapies for DMD
T Yokota, W Duddy, T Partridge
Acta Myologica 26 (3), 179–184, 2007
932007
Long-term efficacy of systemic multiexon skipping targeting dystrophin exons 45–55 with a cocktail of vivo-morpholinos in mdx52 mice
Y Echigoya, Y Aoki, B Miskew, D Panesar, A Touznik, T Nagata, ...
Molecular Therapy-Nucleic Acids 4, e225, 2015
852015
Extensive and Prolonged Restoration of Dystrophin Expression with Vivo-Morpholino-Mediated Multiple Exon Skipping in Dystrophic Dogs
T Yokota, A Nakamura, T Nagata, T Saito, M Kobayashi, Y Aoki, ...
nucleic acid therapeutics 22 (5), 306-315, 2012
842012
Optimization of antisense-mediated exon skipping for Duchenne muscular dystrophy
K Dzierlega, T Yokota
Gene Therapy, 2020
812020
Viltolarsen for the treatment of Duchenne muscular dystrophy
RR Roshmi, T Yokota
Drugs Today 55 (10), 627-639, 2019
772019
Multiple Exon Skipping in the Duchenne Muscular Dystrophy Hot Spots: Prospects and Challenges
Y Echigoya, KRQ Lim, A Nakamura, T Yokota
Journal of Personalized Medicine 8 (4), 41, 2018
772018
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