Human RAP1 inhibits non‐homologous end joining at telomeres J Sarthy, NS Bae, J Scrafford, P Baumann The EMBO journal 28 (21), 3390-3399, 2009 | 176 | 2009 |
Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression SJ Wu, SN Furlan, AB Mihalas, HS Kaya-Okur, AH Feroze, SN Emerson, ... Nature biotechnology 39 (7), 819-824, 2021 | 145 | 2021 |
MYCN amplification and ATRX mutations are incompatible in neuroblastoma M Zeineldin, S Federico, X Chen, Y Fan, B Xu, E Stewart, X Zhou, J Jeon, ... Nature communications 11 (1), 913, 2020 | 108 | 2020 |
Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs DH Janssens, SJ Wu, JF Sarthy, MP Meers, CH Myers, JM Olson, ... Epigenetics & chromatin 11, 1-14, 2018 | 65 | 2018 |
Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models NA Vitanza, MC Biery, C Myers, E Ferguson, Y Zheng, EJ Girard, ... Neuro-oncology 23 (3), 376-386, 2021 | 59 | 2021 |
Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia DH Janssens, MP Meers, SJ Wu, E Babaeva, S Meshinchi, JF Sarthy, ... Nature genetics 53 (11), 1586-1596, 2021 | 51 | 2021 |
Histone deposition pathways determine the chromatin landscapes of H3. 1 and H3. 3 K27M oncohistones JF Sarthy, MP Meers, DH Janssens, JG Henikoff, H Feldman, ... Elife 9, e61090, 2020 | 48 | 2020 |
Short H2A histone variants are expressed in cancer GL Chew, M Bleakley, RK Bradley, HS Malik, S Henikoff, A Molaro, ... Nature communications 12 (1), 490, 2021 | 39 | 2021 |
Poor outcome with hematopoietic stem cell transplantation for bone marrow failure and MDS with severe MIRAGE syndrome phenotype J Sarthy, J Zha, D Babushok, A Shenoy, JM Fan, G Wertheim, ... Blood advances 2 (2), 120-125, 2018 | 38 | 2018 |
Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes N De Sarkar, RD Patton, AL Doebley, B Hanratty, M Adil, AJ Kreitzman, ... Cancer discovery 13 (3), 632-653, 2023 | 27 | 2023 |
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target Q Le, B Hadland, JL Smith, A Leonti, BJ Huang, R Ries, TA Hylkema, ... The Journal of clinical investigation 132 (22), 2022 | 23 | 2022 |
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region S Levy, L Somasundaram, IX Raj, D Ic-Mex, A Phal, S Schmidt, WI Ng, ... Cell reports 38 (9), 2022 | 22 | 2022 |
Automated Parallel Oocyte Electrophysiology Test Station (POETs™): A Screening Platform for Identification of Ligand-Gated Ion Channel Modulators CC Shieh, JD Trumbull, JF Sarthy, DG McKenna, AS Parihar, XF Zhang, ... Assay and Drug Development Technologies 1 (5), 655-663, 2003 | 20 | 2003 |
EWS:: FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma AA Apfelbaum, F Wu, AG Hawkins, B Magnuson, JA Jiménez, SD Taylor, ... Clinical Cancer Research 28 (20), 4466-4478, 2022 | 16 | 2022 |
Response to pembrolizumab in a patient with xeroderma pigmentosum and advanced squamous cell carcinoma A Steineck, N Krumm, JF Sarthy, CC Pritchard, T Chapman, AW Stacey, ... JCO Precision Oncology 3, 2019 | 14 | 2019 |
Chromatin bottlenecks in cancer JF Sarthy, S Henikoff, K Ahmad Trends in cancer 5 (3), 183-194, 2019 | 13 | 2019 |
Apollo—Taking the Lead in Telomere Protection JF Sarthy, P Baumann Molecular cell 39 (4), 489-491, 2010 | 13 | 2010 |
Single-cell analysis of chromatin silencing programs in development and tumor progression SJ Wu, SN Furlan, AB Mihalas, HS Kaya-Okur, AH Feroze, SN Emerson, ... Biorxiv, 2020.09. 04.282418, 2020 | 9 | 2020 |
A light scattering assay for arachidonic acid-induced tau fibrillization without interfering micellization J Sarthy, TC Gamblin Analytical biochemistry 1 (353), 150-152, 2006 | 8 | 2006 |
Pyogenic liver abscess caused by Streptococcus mitis J Sarthy, D DiBardino The Lancet Infectious Diseases 13 (9), 822, 2013 | 6 | 2013 |