| Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification L Liu, X Liu, X Ren, Y Tian, Z Chen, X Xu, Y Du, C Jiang, Y Fang, Z Liu, ... Scientific reports 6 (1), 21602, 2016 | 118 | 2016 |
| Efficient CRISPR/Cas9-mediated versatile, predictable, and donor-free gene knockout in human pluripotent stem cells Z Liu, Y Hui, L Shi, Z Chen, X Xu, L Chi, B Fan, Y Fang, Y Liu, L Ma, ... Stem cell reports 7 (3), 496-507, 2016 | 58 | 2016 |
| Generation of hypoimmunogenic human pluripotent stem cells via expression of membrane-bound and secreted β2m-HLA-G fusion proteins L Shi, W Li, Y Liu, Z Chen, Y Hui, P Hao, X Xu, S Zhang, H Feng, B Zhang, ... Stem Cells 38 (11), 1423-1437, 2020 | 45 | 2020 |
| Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis Y Fang, Z Liu, Z Chen, X Xu, M Xiao, Y Yu, Y Zhang, X Zhang, Y Du, ... Cell Research 27 (9), 1083-1099, 2017 | 45 | 2017 |
| The dorsoventral patterning of human forebrain follows an activation/transformation model L Chi, B Fan, D Feng, Z Chen, Z Liu, Y Hui, X Xu, L Ma, Y Fang, Q Zhang, ... Cerebral Cortex 27 (5), 2941-2954, 2017 | 39 | 2017 |
| Protection of ZIKV infection-induced neuropathy by abrogation of acute antiviral response in human neural progenitors L Liu, Z Chen, X Zhang, S Li, Y Hui, H Feng, Y Du, G Jin, X Zhou, X Zhang Cell Death & Differentiation 26 (12), 2607-2621, 2019 | 37 | 2019 |
| Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment Y Du, Z Liu, X Cao, X Chen, Z Chen, X Zhang, X Zhang, C Jiang Cell Death & Differentiation 24 (6), 1121-1131, 2017 | 30 | 2017 |
| Impaired lipid metabolism in astrocytes underlies degeneration of cortical projection neurons in hereditary spastic paraplegia Y Mou, Y Dong, Z Chen, KR Denton, MO Duff, C Blackstone, SC Zhang, ... Acta Neuropathologica Communications 8, 1-20, 2020 | 28 | 2020 |
| WNT/NOTCH pathway is essential for the maintenance and expansion of human MGE progenitors L Ma, Y Wang, Y Hui, Y Du, Z Chen, H Feng, S Zhang, N Li, J Song, ... Stem Cell Reports 12 (5), 934-949, 2019 | 25 | 2019 |
| Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells L Chi, B Fan, K Zhang, Y Du, Z Liu, Y Fang, Z Chen, X Ren, X Xu, C Jiang, ... Stem Cell Reports 7 (5), 941-954, 2016 | 25 | 2016 |
| Inhibiting mitochondrial fission rescues degeneration in hereditary spastic paraplegia neurons Z Chen, E Chai, Y Mou, RH Roda, C Blackstone, XJ Li Brain 145 (11), 4016-4031, 2022 | 21 | 2022 |
| Genetic engineering of human embryonic stem cells for precise cell fate tracing during human lineage development Z Chen, X Ren, X Xu, X Zhang, Y Hui, Z Liu, L Shi, Y Fang, L Ma, Y Liu, ... Stem cell reports 11 (5), 1257-1271, 2018 | 20 | 2018 |
| MFN2 deficiency impairs mitochondrial transport and downregulates motor protein expression in human spinal motor neurons Y Mou, J Dein, Z Chen, M Jagdale, XJ Li Frontiers in Molecular Neuroscience 14, 727552, 2021 | 18 | 2021 |
| Stem cell models and gene targeting for human motor neuron diseases Y Karpe, Z Chen, XJ Li Pharmaceuticals 14 (6), 565, 2021 | 13 | 2021 |
| Mapping germ-layer specification preventing genes in hPSCs via genome-scale CRISPR screening X Xu, Y Du, L Ma, S Zhang, L Shi, Z Chen, Z Zhou, Y Hui, Y Liu, Y Fang, ... Iscience 24 (1), 2021 | 6 | 2021 |
| Liver-X-receptor agonists rescue axonal degeneration in SPG11-deficient neurons via regulating cholesterol trafficking E Chai, Z Chen, Y Mou, G Thakur, W Zhan, XJ Li Neurobiology of disease 187, 106293, 2023 | 5 | 2023 |
| Chenodeoxycholic acid rescues axonal degeneration in induced pluripotent stem cell-derived neurons from spastic paraplegia type 5 and cerebrotendinous xanthomatosis patients Y Mou, G Nandi, S Mukte, E Chai, Z Chen, JE Nielsen, TT Nielsen, ... Orphanet Journal of Rare Diseases 18 (1), 72, 2023 | 4 | 2023 |
| 靶向胆固醇转运减轻遗传性痉挛性截瘫轴突变性 Z Chen, XJ Li 中国神经再生研究 (英文版) 20 (5), 1397, 2025 | | 2025 |
| Targeting cholesterol trafficking to mitigate axonal degeneration in hereditary spastic paraplegia Z Chen, XJ Li Neural Regeneration Research 20 (5), 1397-1398, 2025 | | 2025 |
| Modeling hereditary spastic paraplegias using induced pluripotent stem cells Y Mou, Z Chen, XJ Li Current Progress in iPSC Disease Modeling, 185-215, 2022 | | 2022 |
