MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates Y Dondelinger, W Declercq, S Montessuit, R Roelandt, A Goncalves, ... Cell reports 7 (4), 971-981, 2014 | 836 | 2014 |
NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling Y Dondelinger, S Jouan-Lanhouet, T Divert, E Theatre, J Bertin, PJ Gough, ... Molecular cell 60 (1), 63-76, 2015 | 431 | 2015 |
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition Y Dondelinger, MA Aguileta, V Goossens, C Dubuisson, S Grootjans, ... Cell Death & Differentiation 20 (10), 1381-1392, 2013 | 340 | 2013 |
Determination of apoptotic and necrotic cell death in vitro and in vivo TV Berghe, S Grootjans, V Goossens, Y Dondelinger, DV Krysko, ... Methods 61 (2), 117-129, 2013 | 291 | 2013 |
Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis Q Remijsen, V Goossens, S Grootjans, C Van Den Haute, ... Cell death & disease 5 (1), e1004-e1004, 2014 | 218 | 2014 |
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death Y Dondelinger, T Delanghe, D Rojas-Rivera, D Priem, T Delvaeye, ... Nature cell biology 19 (10), 1237-1247, 2017 | 195 | 2017 |
CHIP controls necroptosis through ubiquitylation-and lysosome-dependent degradation of RIPK3 J Seo, EW Lee, H Sung, D Seong, Y Dondelinger, J Shin, M Jeong, ... Nature cell biology 18 (3), 291-302, 2016 | 172 | 2016 |
Poly-ubiquitination in TNFR1-mediated necroptosis Y Dondelinger, M Darding, MJM Bertrand, H Walczak Cellular and Molecular Life Sciences 73, 2165-2176, 2016 | 165 | 2016 |
Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation Y Dondelinger, T Delanghe, D Priem, MA Wynosky-Dolfi, D Sorobetea, ... Nature communications 10 (1), 1729, 2019 | 150 | 2019 |
An evolutionary perspective on the necroptotic pathway Y Dondelinger, P Hulpiau, Y Saeys, MJM Bertrand, P Vandenabeele Trends in Cell Biology 26 (10), 721-732, 2016 | 143 | 2016 |
RIPK1 Kinase-Dependent Death: A Symphony of Phosphorylation Events T Delanghe, Y Dondelinger, MJM Bertrand Trends in Cell Biology 30 (3), 189-200, 2020 | 116 | 2020 |
Respiratory Syncytial Virus Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells J Simpson, Z Loh, MA Ullah, JP Lynch, RB Werder, N Collinson, V Zhang, ... American Journal of Respiratory and Critical Care Medicine 201 (11), 1358-1371, 2020 | 106 | 2020 |
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease C Rigauts, J Aizawa, SL Taylor, GB Rogers, M Govaerts, P Cos, L Ostyn, ... European Respiratory Journal 59 (5), 2022 | 92 | 2022 |
A real-time fluorometric method for the simultaneous detection of cell death type and rate S Grootjans, B Hassannia, I Delrue, V Goossens, B Wiernicki, ... Nature protocols 11 (8), 1444-1454, 2016 | 63 | 2016 |
Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis L Duprez, MJM Bertrand, TV Berghe, Y Dondelinger, N Festjens, ... Journal of Biological Chemistry 287 (18), 14863-14872, 2012 | 59 | 2012 |
Regulation of RIPK1's cell death function by phosphorylation Y Dondelinger, P Vandenabeele, MJM Bertrand Cell Cycle 15 (1), 5-6, 2016 | 23 | 2016 |
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD HP Van Eeckhoutte, C Donovan, RY Kim, TM Conlon, M Ansari, H Khan, ... European Respiratory Journal 61 (4), 2023 | 22 | 2023 |
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor T Delanghe, J Huyghe, S Lee, D Priem, S Van Coillie, B Gilbert, SM Choi, ... Cell Death & Disease 12 (7), 699, 2021 | 20 | 2021 |
N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis Y Estornes, Y Dondelinger, K Weber, I Bruggeman, A Peall, ... Cell death & disease 9 (5), 494, 2018 | 20 | 2018 |
MK2 puts an additional brake on RIPK1 cytotoxic potential Y Dondelinger, T Delanghe, MMJ Bertrand Cell death and differentiation 25 (3), 457, 2018 | 8 | 2018 |