Repurposing bedaquiline for effective non-small cell lung cancer (NSCLC) therapy as inhalable cyclodextrin-based molecular inclusion complexes V Parvathaneni, RS Elbatanony, M Goyal, T Chavan, N Vega, S Kolluru, ... International journal of molecular sciences 22 (9), 4783, 2021 | 28 | 2021 |
The diverse bioactivity of α-mangostin and its therapeutic implications T Chavan, A Muth Future Medicinal Chemistry 13 (19), 1679-1694, 2021 | 20 | 2021 |
Effect of spray drying on amorphization of indomethacin nicotinamide cocrystals; optimization, characterization, and stability study HM Tawfeek, T Chavan, NK Kunda AAPS PharmSciTech 21, 1-13, 2020 | 14 | 2020 |
Solubility enhancement and inhalation delivery of cyclodextrin-based inclusion complex of delamanid for pulmonary tuberculosis treatment SM Patil, DS Barji, T Chavan, K Patel, AJ Collazo, V Prithipaul, A Muth, ... AAPS PharmSciTech 24 (1), 49, 2023 | 10 | 2023 |
Small-molecule Gankyrin inhibition as a therapeutic strategy for breast and lung cancer D Kanabar, M Goyal, EI Kane, T Chavan, A Kabir, X Wang, S Shukla, ... Journal of medicinal chemistry 65 (13), 8975-8997, 2022 | 8 | 2022 |
Introduction to nanomedicine in drug delivery T Chavan, P Muttil, NK Kunda Mucosal Delivery of Drugs and Biologics in Nanoparticles, 3-26, 2020 | 6 | 2020 |
Poly vinyl pyrrolidone (PVP) based inhaled delivery carriers for olaparib for non-small cell lung cancer (NSCLC) treatment M Goyal, G Tulsyan, DD Kanabar, T Chavan, A Muth, V Gupta Journal of Drug Delivery Science and Technology 87, 104767, 2023 | 5 | 2023 |
Identification of novel gankyrin binding scaffolds by high throughput virtual screening. D Kanabar, A Kabir, T Chavan, J Kong, S Yoganathan, A Muth Bioorganic & Medicinal Chemistry Letters 43, 128043-128043, 2021 | 3 | 2021 |
Structural modification of the propyl linker of cjoc42 in combination with sulfonate ester and triazole replacements for enhanced gankyrin binding and anti-proliferative activity T Chavan, D Kanabar, K Patel, TM Laflamme, M Riyazi, DE Spratt, A Muth Bioorganic & Medicinal Chemistry 110, 117836, 2024 | | 2024 |
Synthesis and evaluation of 2, 5-substituted pyrimidines as small-molecule gankyrin binders D Kanabar, EI Kane, T Chavan, TM Laflamme, E Suarez, M Goyal, ... Future Medicinal Chemistry 16 (3), 239-251, 2024 | | 2024 |
Targeting the Oncoprotein Gankyrin with Small Molecules to Alter its 3D Global Fold M Riyazi, T Laflamme, E Kane, D Kanabar, T Chavan, A Muth, DE Spratt PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
Specificity studies of small molecule inhibitors targeting the ankyrin-repeat oncoprotein gankyrin T Laflamme, E Kane, DE Spratt, A Muth, D Kanabar, T Chavan PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
Structural Modification of the Propyl Linker of Cjoc42 for Enhanced Gankyrin Binding and Anti-cancer Activity T Chavan | | 2022 |
Development of conformationally constrained cjoc42 derivatives for binding gankyrin T Chavan, A Muth American Chemical Society SciMeetings 1 (1), 2020 | | 2020 |